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Conceptual Immunology at the Salk Institute

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Conceptual Immunology at the Salk Institute | cig.salk.edu Reviews

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Feel free to e-mail. Any questions or comments to: mata@salk.edu.

INTERNAL PAGES

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1

Protecton

http://cig.salk.edu/protect_html/protect.html

Protecton Notes and Introduction:. Skip the blurb and jump in. Three key elements are needed to make the concept work. First is the concentration dependence of antibody function. Second is the limited amount of antibody a B cell can secrete in a day. Third is limited amount of time available to reach a sufficient concentration of antibody to be protective (the pathogens are dividing all the time and can kill the host before a protective concentration is reached). In short, there is no universal Protecton...

2

CIG-Papers

http://cig.salk.edu/papers/papers.html

These are all Melvin Cohn's publications, including current papers in preparation. If the there is a link to a .pdf file, any comments would be greatly appreciated and will be used to improve the text before submission to publication. When accepted for publication the paper will be removed from this site. Address comments to cohn@salk.edu. 5 Cohn, M. and Monod, J. (1951) Purification et proprietes de la β-galactosidase (lactase) d'Escherichia coli. Biochim. Biophys. Acta 7:153-174. 6 Cohn, M. and Tor...

3

Introduction

http://cig.salk.edu/sis-II/sis.html

Go to the Rules Authoring Tool. When asked for a password, use guest or guest1. Or live dangerously on the Expert Page. Which is set up with rules explained below. Click on Rules Authoring Tool. Click on Submit Rules - a default set of rules is provided. Give the password guest, guest1 or guest2 (if others are using the guest password). Click on Begin Simulation - an Autoimmunity test was performed for you. Click on Initialize Simulator - providing you pass the Autoimmunity test. An implicit feature in e...

4

Useful Math Tools

http://cig.salk.edu/MathUtils/MathUtils.html

Return to CIG Home Page.

5

Ig Genesis Time Model

http://cig.salk.edu/IgGenesis/IgGenesisModel.html

The Genesis of primer Ig and the Self-Nonself Model of Antibody Regulation. Calculating the parameters and boundary conditions for the antigen independent pathway for the origin of primer antibody. Links to the Ig-genesis program. The requirement for primer antibody arises from the following reasoning:. Mutation) but an intact innate (germline-encoded) defense system. These individuals succumb to infection by organisms not recognized by the innate defense system. The formation of which is dependent on th...

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Conceptual Immunology at the Salk Institute

Feel free to e-mail. Any questions or comments to: mata@salk.edu.

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