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Acelot, Inc.

Improved Disease-modifying Therapies Through Joint Pharmacophore Mining. Acelot is a life science based R&D company focusing on advanced technology for drug discovery. This technology is made available both as an easy-to-use web-based drug discovery platform, as well as employed in-house for a number of drug-discovery projects in the central nervous system area. Acelot also provides on-site or remote drug discovery services. Acelot's own JPS-powered drug discovery pipeline. May 7, 2014. December 3, 2013.

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Improved Disease-modifying Therapies Through Joint Pharmacophore Mining. Acelot is a life science based R&D company focusing on advanced technology for drug discovery. This technology is made available both as an easy-to-use web-based drug discovery platform, as well as employed in-house for a number of drug-discovery projects in the central nervous system area. Acelot also provides on-site or remote drug discovery services. Acelot's own JPS-powered drug discovery pipeline. May 7, 2014. December 3, 2013.
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Acelot, Inc. | acelot.com Reviews

https://acelot.com

Improved Disease-modifying Therapies Through Joint Pharmacophore Mining. Acelot is a life science based R&D company focusing on advanced technology for drug discovery. This technology is made available both as an easy-to-use web-based drug discovery platform, as well as employed in-house for a number of drug-discovery projects in the central nervous system area. Acelot also provides on-site or remote drug discovery services. Acelot's own JPS-powered drug discovery pipeline. May 7, 2014. December 3, 2013.

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Acelot, Inc.

http://www.acelot.com/services.html

Acelot offers on-site or remote services for a variety of drug development tasks:. Target identification based on pathway analysis. Pharmacophore development based on ligand/binding site structure. Drug repurposing using biological pathway and binding data. Structure-activity interpretation and optimization. Leadlikeness and druglikeness determination and filtering. Optimization of drug candidates: PKDM, ADME/Tox. Compound database mining for substructure motifs. LEADS™: Web-based Drug Discovery. If you ...

2

Acelot, Inc.

http://www.acelot.com/science.html

JPS: The Science Behind Acelot's Leads. Acelot applies patented graph-mining algorithms to the chemical space in order to identify structural properties relevant to a desired activity or binding. At the core of these algorithms is the so-called "Joint Pharmacophore Space" (JPS), a collection of all 3D pharmacophoric point constellations from multiple ligands and/or multiple targets. This is a very powerful way to reach a set of high-quality druglike lead candidates in a very short time. It shows that JPS...

3

Acelot, Inc.

http://www.acelot.com/index.html

Improved Disease-modifying Therapies Through Joint Pharmacophore Mining. Acelot is a life science based R&D company focusing on advanced technology for drug discovery. This technology is made available both as an easy-to-use web-based drug discovery platform, as well as employed in-house for a number of drug-discovery projects in the central nervous system area. Acelot also provides on-site or remote drug discovery services. Acelot's own JPS-powered drug discovery pipeline. December 22, 2015. May 31, 2015.

4

Acelot, Inc.

http://www.acelot.com/drug_discovery.html

Current Drug Discovery Pipeline. Acelot constantly aquires, curates, and analyzes large amounts of biological and chemical data to discover new and promising drug targets and small molecules that can act on these targets with high efficacy and minimal side-effects. This discovery effort is facilitated by Acelot's proprietary computer-aided searching and data mining tools that are unique in the industry. Currently, Acelot is exploring the following drug targets (click on targets to learn more):. With the ...

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Current Members — Molecular Graphics Lab

http://mgl.scripps.edu/group-members

Arthur J. Olson, Ph.D. MGL Director; Professor, Dept of ISCB. Olson -at- scripps.edu. Michael E. Pique. Director, Graphics Development. Mp -at- scripps.edu. David S. Goodsell, Ph.D. Associate Professor of Molecular Biology. Goodsell -at- scripps.edu. Michel Sanner Ph.D. Associate Professor of Molecular Biology. Sanner -at- scripps.edu. Stefano Forli, Ph.D. Assistant Professor of ISCB. Bob Rosenstein, Ph.D. Rdr -at- scripps.edu. Sr Research Admin. Assistant. Theresam -at- scripps.edu. Richard K. Belew.

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UCSB Startups – UCSB Office of Technology & Industry Alliances

http://tia.ucsb.edu/entrepreneurs/pastpresent-ucsb-startups

Darr; Skip to Main Content. Facts & Figures – TIA. Forms & Policies. Top Tips for Working with Industry. Facilities for External Use. Facilities for External Use. Below is a selection of startups that have been formed around technology and research developed at UCSB. Santa Barbara, CA. Santa Barbara, CA. Santa Barbara, CA. Santa Barbara, CA. Medical Diagnostics – Aptamers. Silicon Photonic Integrated Circuits. Santa Barbara, CA. Westlake Village, CA. Glen Burnie, MD. Santa Barbara, CA. Santa Barbara, CA.

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Improved Disease-modifying Therapies Through Joint Pharmacophore Mining. Acelot is a life science based R&D company focusing on advanced technology for drug discovery. This technology is made available both as an easy-to-use web-based drug discovery platform, as well as employed in-house for a number of drug-discovery projects in the central nervous system area. Acelot also provides on-site or remote drug discovery services. Acelot's own JPS-powered drug discovery pipeline. May 7, 2014. December 3, 2013.

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