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Kinacept is a cooperative project in which small drug discovery companies from Germany, Austria and the UK work with European Research Institutes on new therapies for inflammatory diseases.

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Home - Kinacept | actakine.com Reviews
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Kinacept is a cooperative project in which small drug discovery companies from Germany, Austria and the UK work with European Research Institutes on new therapies for inflammatory diseases.
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1 Anti-inflamatory drugs
2 p38
3 medicinal chemistry
4 pharmacology
5 IBD
6 Crohn's
7 arthritis
8 cancer
9 pancreas cancer
10 bone erosion
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project goals,news,main results,team,licensing opportunities,impressum,our targets include,inflammatory bowel disease,rheumatoid arthritis,glomerulonephritis
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Home - Kinacept | actakine.com Reviews

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Kinacept is a cooperative project in which small drug discovery companies from Germany, Austria and the UK work with European Research Institutes on new therapies for inflammatory diseases.

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Home - Kinacept

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New ideas for inflammatory diseases. Welcome to the KINACEPT project Website. KINACEPT is a project sponsored by the European Commission with the objective of discovering novel therapies for severe inflammatory diseases. Cancers of Inflammatory Origin, and,. The Project Team is composed of Companies and Institutes engaged in novel drug discovery using modern structure based drug design to discover selective and well tolerated drugs. SMEs working together for new products.

2

Main Results - Kinacept

http://www.actakine.com/4.html

New ideas for inflammatory diseases. Treatments for rheumatoid arthritisResults. The project has had three main results:. The project has identified means to select patients with a significant response to the substances based on a small blood sample. In generating these data, it was possible to demonstrate that lesion biopsy was not necessary to obtain this information thus potentially sparing intrusive examinations. Publications of the project:. 2] P38 MAP kinase triggers dendritic or accessory cells in...

3

News - Kinacept

http://www.actakine.com/3.html

New ideas for inflammatory diseases. JAK inhibitors looking good. BRAF is a key target in certain melanomas. Pfizer's JAK inhibitor tofacitinib succeeds in Phase III. Synovo receives provisional approval for ca. 1 M Euro in cancer development funds. IKP stuttgart leads a major network of European Pharmacologists. SMEs working together for new products.

4

Licensing opportunities - Kinacept

http://www.actakine.com/11.html

New ideas for inflammatory diseases. Novel, orally available, non-cytotoxics with a very wide therapeutic index and excellent safety in man. Novel macrocyle with excellent safety profile and broad anti-inflammatory efficacy. SMEs working together for new products.

5

Project goals - Kinacept

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New ideas for inflammatory diseases. Discover new, selective well tolerated kinase inhbitors. Use modern pathophysiological techniques to match them to specific diseases. Validate and develop the compounds as candidate drugs. The consortium has a lead series of kinase inhibitors with unusual anti-inflammatory properties. A key issue in bringing substances of this class to the clinic is variable patient response to kinase inhibitors in previous trials. SMEs working together for new products.

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