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A multi-centre randomised trial of autologous chondrocyte transplantation/implantation versus existing treatments (ACTIVE) for chondral defects in the knee.

http://active-trial.org.uk/

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Homepage | active-trial.org.uk Reviews
<META>
DESCRIPTION
A multi-centre randomised trial of autologous chondrocyte transplantation/implantation versus existing treatments (ACTIVE) for chondral defects in the knee.
<META>
KEYWORDS
1 autologous
2 chondrocyte
3 cartilage
4 tissue engineering
5 oswestry
6 orthopaedics
7 ACTIVE
8 ACTIVE trial
9 articular cartilage defects
10 knee
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utologous,hondrocyte,ransplantation /,mplantation,ersus,xisting treatments,participants,chondral defects,why active,which hospitals,your participation,professionals,news,people,study documents,surgeons,local coordinators,assessors,rehab physios,funding
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Homepage | active-trial.org.uk Reviews

https://active-trial.org.uk

A multi-centre randomised trial of autologous chondrocyte transplantation/implantation versus existing treatments (ACTIVE) for chondral defects in the knee.

INTERNAL PAGES

active-trial.org.uk active-trial.org.uk
1

Assessors

http://active-trial.org.uk/Assessors.htm

Most hospitals have already recruited an assessor. Assessors' names can be viewed along with the other local ACTIVE team members on the Which hospitals? What does an Independent Assessor do? Please click on the bullet points below for guidance on what to do. Organise trial patients’ visits to the clinic and carry out assessments at the proper time. Arrange for patients to claim travel expenses. General Guidelines for Semi-Structured Interviewing. Physical and Functional Assessment. 12 You contact the pat...

2

Chondral defects

http://active-trial.org.uk/ChondralDefects.htm

What is a chondral defect? What does articular cartilage do? Articular cartilage is a tough, smooth, elastic tissue which covers the ends of bones that form joints. It enables the bones to move smoothly over one another and acts as a shock absorber, cushioning the bone from forces of more than five times the body's weight. Damaged articular cartilage in knees can cause the joint to be painful, swollen and difficult to move. Why doesn't it mend itself? What is the best treatment? Debridement is a rather b...

3

Surgeons

http://active-trial.org.uk/Surgeons.htm

ACTIVE surgeons are listed here. Along with their local team members. All ACTIVE surgeons must have previous experience of performing the techniques used in the trial before starting recruitment. If you are a surgeon wanting to participate you can gain the necessary experience with ACI by visiting the RJAH Orthopaedic Hospital and assisting Professor James Richardson. To arrange a visit please contact the Trial Manager. When you have a patient that meets the Patient Entry Criteria. 3 The trial is randomi...

4

Coordinators

http://active-trial.org.uk/Coordinators.htm

Why do we have local study co-ordinators? Most hospitals have already recruited a co-ordinator. Co-ordinators' names can be viewed along with the other local ACTIVE team members on the Which hospitals? What does a local study co-ordinator do? Please click on the bullet points below for guidance on what to do. It is important that you follow the correct protocol for entering patients into the trial as summarised in the trial schema. You should also familiarise yourself with the Patient Information Leaflet.

5

Funding

http://active-trial.org.uk/Funding.htm

ACTIVE is funded by the Medical Research Council (MRC). The funds are administered by Keele University. The Department of Health (DoH) are funding approximately 90% of the. Treatment costs, i.e. 90% of the estimated difference between the standard surgical procedures used in one arm of the trial and the more expensive ACI treatment used in the other arm of the trial. The Collaborator Agreement must be signed by your Trust and Keele University before funding will be paid. Treatment costs (UK only). How ca...

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LINKS TO THIS WEBSITE

kneeandhipsurgery.co.uk kneeandhipsurgery.co.uk

Cartilage Transplantation | Rob Pollock, Consultant Orthopaedic Surgeon | Knee & Hip Surgery London

http://www.kneeandhipsurgery.co.uk/cartilage-transplantation.php

Profiles of the team. Osteoarthritis of the Knee. Osteoarthritis of the Hip. Your Admission to Hospital. Bone and Soft Tissue Tumours. Some people, particularly adolescents and young adults, suffer injuries to the actual surface of the knee joint. If left untreated, the knee often becomes painful and swollen. In severe cases osteoarthritis may develop. Various treatments are available ranging from simple drilling of the defect through to cartilage transplantation.

northwaleskneeclinic.co.uk northwaleskneeclinic.co.uk

Useful Knee Surgery website links from the North Wales Knee Clinic

http://northwaleskneeclinic.co.uk/links.html

Mr Tony Smith FRCS ORTH. Email: info@northwaleskneeclinic.co.uk. The North Wales Knee Clinic. Spire Yale hospital, Wrexham Technology Park, Croesnewydd Road, Wrexham, LL13 7YP.

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Homepage

The ACTIVE Trial is no longer recruiting new participants, however we may be running other studies that might interest you. Please contact the trial manager on 01691 404142 or email johanna.wales@rjah.nhs.uk. Information for participants, including Trial newsletters, can be found under Participants on the left of this page. Nformation for trial site staff, inlcuding current versions of trial related documents and forms are available in the section under Professionals on the left of this page.

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