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Home Page | Aeglea BiotherapeuticsExploiting Errors in Metabolism to Advance Treatment of Human Disease. Developing variants on human enzymes to deplete key amino acids driving human disease.
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Exploiting Errors in Metabolism to Advance Treatment of Human Disease. Developing variants on human enzymes to deplete key amino acids driving human disease.
http://www.aegleabio.com/
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United States
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Home Page | Aeglea Biotherapeutics | aegleabio.com Reviews
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Exploiting Errors in Metabolism to Advance Treatment of Human Disease. Developing variants on human enzymes to deplete key amino acids driving human disease.
Aeglea Biotherapeutics - Investors - Investors
Patients and Caregivers Overview. As of 01/11/17 4:00 pm ET. Data provided by Nasdaq. Minimum 15 minutes delayed. Aeglea BioTherapeutics to Present at BMO Capital Markets Prescription for Success Healthcare Conference. AUSTIN, Texas, Dec. 07, 2016 (GLOBE NEWSWIRE) - Aeglea BioTherapeutics, Inc. (NASDAQ:AGLE), a biotechnology company committed to developing enzyme-based therapeutics in the field of amino acid metabolism to treat genetic rare diseases and cancer,. There are currently no events scheduled.
aegleabio.com
Board Members | Aeglea Biotherapeutics
http://www.aegleabio.com/about/board
David G Lowe, Ph.D., Co-Founder, President and Chief Executive Officer. Russell J Cox, Executive Vice President and Chief Operating Officer, Jazz Pharmaceuticals. Professor George Georgiou, Ph.D., Co-Founder. Sandy Mahatme, Senior Vice President and Chief Financial Officer, Sarepta Therapeutics. Anthony Quinn, M.B Ch.B, Ph.D., FRCP. Armen Shanafelt, Ph.D., Lilly Ventures.
Team | Aeglea Biotherapeutics
http://www.aegleabio.com/about/team
David G Lowe, Ph.D., Co-Founder, President and Chief Executive Officer. Sandra Rojas-Caro, M.D., Chief Medical Officer. Charles N York, M.B.A., Chief Financial Officer. Henry L Hebel, M.B.A., Vice President of Product Development. Scott W Rowlinson, Ph.D., Vice President of Research. Joseph E Tyler, M.S., Vice President of Manufacturing.
Mission | Aeglea Biotherapeutics
http://www.aegleabio.com/about/mission
DEDICATED TO DEVELOPING NOVEL TREATMENTS FOR INBORN ERRORS OF METABOLISM AND CANCER. We hope to achieve this through:. Effecting enzyme replacement therapy in patients with inborn errors of metabolism using engineered human amino acid degrading enzymes. Exploiting abnormal amino acid metabolism in cancer cells to selectively target tumors. Applying molecular biomarkers to the identification of cancer patients with tumors that have metabolic vulnerabilities in amino acid metabolism.
AECase Cysteine degradation Enzyme | Aeglea Biotherapeutics
http://www.aegleabio.com/pipeline/aecase-cysteine-degradation
Targeting cysteine/cystine and oxidative stress for oncology.
AERase Arginine Degradation Enzyme | Aeglea Biotherapeutics
http://www.aegleabio.com/pipeline/aerase-arginine-degradation
MODULATION OF ARGININE LEVELS. Aeglea BioTherapeutics’s lead product candidate, AEB1102, is derived from human Arginase I. Modifications, which include the substitution of cobalt for the manganese cofactor and PEGylation, impart on AEB1102 both increased catalytic activity and serum stability compared to native Arginase I, making it potentially suitable as a therapeutic for the degradation of arginine in the circulation. AEB1102 as a potential treatment for extremes of Arginine metabolism.
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The University of Texas at Austin. Bureau of Business Research. ICTPI: International Conference on Technology Policy and Innovation. Converting Technology to Wealth: Technology Transfer Training. FASTFORWARD Small Business Training. Maestría en Comercialización (MCCT Mexico). UT Austin Portugal CoLab. Austin Technology Incubator “graduates” raise $220M. August 24, 2016. The Austin Technology Incubator. Wells Fargo is the lead sponsor for the graduation event, which will open with a cocktail reception to ...
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Exploiting Errors in Metabolism to Advance Treatment of Human Disease. Developing variants on human enzymes to deplete key amino acids driving human disease.
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Self Determination for People Living with Long Term Conditions. Our healthcare economies continue to be challenged by rising costs, increasingly attributable to long term conditions. Aegle Care helps empower people to self-manage their long term conditions under the supervision of their health and social care providers. We help people living with long term conditions enjoy life to the fullest, at the same time reduce the cost of their care. Aegle Platform for Patient-Centered Care. Real-time performance ...
