aging-kidney.de
Homeaging kidney
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aging kidney
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aging kidney
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Aging Kidney Group
http://www.aging-kidney.de/aging-kidney-group.html
The population over the age of 65 years will more than double globally within the coming 15 years. This increase of elderly individuals will be paralleled by a sharp rise in renal disease because old kidneys are more susceptible to injury and they loose their capacity to repair. Our goal is to provide new mechanistic insight that is needed to develop preventative strategies and therapeutic treatments for kidney disease especially in the elderly.
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It is our goal to better understand the molecular basis of structural and functional changes that occur in old kidneys during acute and chronic disease. In studying these changes we put special emphasis on the tubulointerstitium, a compartment which comprises the bulk of the kidney. While the aging renal tubular system undergoes atrophy the interstitium increases in mass. This is associated with a progressive loss in renal function. In parallel we aim to translate our findings into clinical applications.
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