The Burge Laboratory web server. Services and sites on genes.mit.edu:. Burge Lab home page. Burge Lab Software Site. Burge Lab supplementary material to publications. Burge Lab web servers. ACEScan [ Genes ]. MaxEnt [ Build ]. Score splice sites ]. About genes.mit.edu:. Genesmit.edu is a Compaq Alpha ES40 server, with four Alpha processors and a lot of RAM. Despite the computing power, the server is often overworked.
http://als-research.mit.edu/
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GENES.MIT.EDU | als-research.mit.edu Reviews
https://als-research.mit.edu
The Burge Laboratory web server. Services and sites on genes.mit.edu:. Burge Lab home page. Burge Lab Software Site. Burge Lab supplementary material to publications. Burge Lab web servers. ACEScan [ Genes ]. MaxEnt [ Build ]. Score splice sites ]. About genes.mit.edu:. Genesmit.edu is a Compaq Alpha ES40 server, with four Alpha processors and a lot of RAM. Despite the computing power, the server is often overworked.
als-research.mit.edu
RESCUE-ESE Web Server
http://als-research.mit.edu/burgelab/rescue-ese
An online tool for identifying candidate ESEs in vertebrate exons. Specific short oligonucleotide sequences that enhance pre-mRNA splicing when present in exons, termed exonic splicing enhancers (ESEs), play important roles in constitutive and alternative splicing ( ESE References. The RESCUE-ESE approach identified 238 hexamers as candidate ESEs. Using a large database of human genes of known exon-intron structure containing over 30,000 nonredudant exons. Enter Your Sequence (RNA or DNA) as plain text.
FAS-ESS web server
http://als-research.mit.edu/fas-ess
Provided by the Burge Lab. You can enter a single sequence or multiple sequences in FASTA format. Non-letters will be removed from sequences. Lowercase letters will be converted to uppercase. T and U are considered the same. Wang, Z., Rolish, M. E., Yeo, G., Tung, V., Mawson, M. and Burge, C. B. (2004). Systematic identification and analysis of exonic splicing silencers. Cell. Please send feedback to Mike Rolish (merolish at mit dot edu).
MiRscan Web Server
http://als-research.mit.edu/mirscan/index.html
If you enter the sequences of two hairpins, MiRscan will assign them a score, based on their similarity to 50 pairs of experimentally verified C. elegans/C. briggsae microRNA hairpins. (See the first reference for details.). Enter lines of the format. Name) ( 100mer) ( 100mer). For example, try copying and pasting the mir-34 human/fugu sequence pair below. (Be sure to include the name.). These authors contributed equally. Thanks to the Vienna RNA Package. Web page by Matt Mawson, Lee Lim, and Nelson Lau.
MaxEntScan::scoresplice
http://als-research.mit.edu/burgelab/maxent/Xmaxentscan_scoreseq.html
For human 5' splice sites. MaxEntScan: score5ss scores 9 mers using different 5'ss models. To score 3' splice sites go to MaxEntScan: score3ss. To build your own MaxEntScan models as described in the paper (below) refer to MaxEntScan: build. References: Yeo G and Burge C.B., Maximum Entropy Modeling of Short Sequence Motifs with Applications to RNA Splicing Signals, RECOMB 2003 (Journal Comp. Bio in press). For questions and comments please email Gene at geneyeo@mit.edu. How to use MaxEntScan: score5ss.
Genome Annotation (GENOA) file Server
http://als-research.mit.edu/genoa/index.html
This is the GENOA file server at MIT, providing access to genome alignments that detect loci and pertinent alternative transcript structures of genes in genomic sequences for the human genome. Related publications and online supplementary material. D Holste, C.B. Burge, et al. The making of mRNAs: computationally dissecting the alternative splicing of precursors by using the Hollywood database. In preparation. World-wide web Supplementary material. Genome Annotation (GENOA) pipeline. Aligns spliced cDNA ...
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ExpressionPlot » About
http://blog.expressionplot.com/about
Exon array and RNA-Seq platforms have emerged as important tools for detecting changes in gene expression and RNA processing in biological samples. We have developed a software package called. That can process both types of data and provides an easy-to-use exploratory web interface. The package consists of a back end, which processes and prepares the raw high-throughput data, and the web-based front end, which allows non-specialists to browse, visualize, and compare different data sets. You can try out.
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GENES.MIT.EDU
The Burge Laboratory web server. Services and sites on genes.mit.edu:. Burge Lab home page. Burge Lab Software Site. Burge Lab supplementary material to publications. Burge Lab web servers. ACEScan [ Genes ]. MaxEnt [ Build ]. Score splice sites ]. About genes.mit.edu:. Genesmit.edu is a Compaq Alpha ES40 server, with four Alpha processors and a lot of RAM. Despite the computing power, the server is often overworked.
ARC: ALS Research Collaboration
How You Can Help. To ARC. Our mission is to work together with families to find a cure for this disease. Interested in ALS Research? Use the map to locate a research study. Open the map and click on the numbered labels and circles to view all clinical trials in that location. To filter the studies:. Select the Table icon in the bottom right hand corner of the map. From the "Viewing" pull down menu at the top of the table, select "ALS Clinical Trials". October 12, 2014:. September 12, 2014:. And other gen...
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