alsresearchcenter.pitt.edu
collaborators
http://www.alsresearchcenter.pitt.edu/people/collaborators.php
Udai Pandey, PhD. Udai Pandey, PhD. View Dr. Pandey’s publications. Where Do I Go From Here? Is Stem Cell Therapy Ready? Improving Nutrition / Swallowing. Occupational and Physical Therapy. Guiding Treatment in ALS. Make a Clinic Appointment. The University of Pittsburgh ALS Tissue Bank. The University of Pittsburgh ALS Tissue Bank.
alsresearchcenter.pitt.edu
News & Events | Center for ALS Research | University of Pittsburgh
http://www.alsresearchcenter.pitt.edu/news
Live Like Lou Center for ALS Research at the University of Pittsburgh Brain Institute. Diaphragm Pacing Program and Study at UPMC. Melatonin Delays Disease Progression in an ALS Mouse Model. Zhang Y, Cook A, Kim K, et al. Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobio Dis 2013; 55:26 35. Mutations account for about half of all cases of familial ALS.
alsresearchcenter.pitt.edu
what_is_als
http://www.alsresearchcenter.pitt.edu/patients/what_is_als.php
May twitch (fasciculate), and sometimes cramp. There may also be involvement of upper motor neurons in the brain. These neurons send their signals through the spinal cord. If they are damaged, the outer or. Spinal cord becomes scarred or. Of ALS is unknown. In 5-10% of patients, the disease is inherited. In all others, it is not. We think that a toxic build-up of some substances (glutamate - an amino acid, or oxygen free radicals) might be important, but other causes are possible. Where Do I Go From Here?
alsresearchcenter.pitt.edu
board_members2
http://www.alsresearchcenter.pitt.edu/people/board_members2.php
Steven Albert, PhD. Steven Albert, PhD. Robert Friedlander, MD, MA. Robert Friedlander, MD. Specialized Areas of Interest. Aneurysms, vascular malformations, brain tumors, carotid disease, cerebrovascular disease, and Chiari malformation. Research focuses on mechanisms of apoptosis; Huntington's disease, ALS, and stroke. Steven Graham, MD, PhD. Steven Graham, MD, PhD. Can be reviewed through the National Library of Medicine's publication database. David Lacomis, MD. David Lacomis, MD. Dr Wechsler earned ...
alsresearchcenter.pitt.edu
aan_guidelines
http://www.alsresearchcenter.pitt.edu/patients/aan_guidelines.php
Guiding Treatment in ALS. The American Academy of Neurology published guidelines for treatment of ALS in October 2009. They are available to patients at www.aan.com. Practice Guidelines (search amyotrophic lateral sclerosis). Specific issues addressed are:. Non-invasive ventilation (e.g. BiPAP). Cough assist type devices. Where Do I Go From Here? Is Stem Cell Therapy Ready? Improving Nutrition / Swallowing. Occupational and Physical Therapy. Guiding Treatment in ALS. Make a Clinic Appointment.
alsresearchcenter.pitt.edu
NutritionalIssues
http://www.alsresearchcenter.pitt.edu/patients/NutritionalIssues.php
Good nutrition is important in both health and disease. The best diet for a patient with ALS is not known, but some people have strong opinions. We do know that our body requires approximately 50 different nutrients to function at its best. It obtains these nutrients from the food and beverages we consume. The proper array of nutrients can be obtained by consuming a balanced diet that includes foods from all the food groups. Choose whole grain breads and cereals with fiber. Choose a variety of colors.
alsresearchcenter.pitt.edu
Support | Center for ALS Research | University of Pittsburgh
http://www.alsresearchcenter.pitt.edu/support/index.php
Your Gift Makes a Difference! Your Gift Makes a Difference. The Cause(s) of ALS is not known; More Research is Needed. Grant Funding is Limited for ALS Research. We Need to Explore Multiple Lines of Investigation and Have the Expertise and Facilities. Time is in Short Supply; Research needs to be Expedited. To Fund our Ambitious, Collaborative Programs, we need Help and Cannot Afford to Wait. What are We Doing with Current Donations? Supportin our Tissue Bank. Purchase medical equipment and supplies.
alsresearchcenter.pitt.edu
People | Center for ALS Research | University of Pittsburgh
http://www.alsresearchcenter.pitt.edu/people
David Lacomis, MD. David Lacomis, MD. Neurology and Pathology. Dr. Lacomis is a member of the editorial board for the Journal of Clinical Neuromuscular Diseases and two scientific advisory committees as well as the Northeastern ALS Consortium. Profiles of each of the specialists from the multidisciplinary team are included below:. Sasha Zivkovic, MD, PhD. Rebecca Molczan, MSN, CRNP. Kathleen Brandfass, MS PT. Director of Neuro, Vestibular and Geriatric Outpatient Services. UPMC /Centers for Rehab Services.
alsresearchcenter.pitt.edu
About | Center for ALS Research | University of Pittsburgh
http://www.alsresearchcenter.pitt.edu/about
Amyotrophic lateral sclerosis (ALS), also known in the U.S. as Lou Gehrig’s disease, is a degenerative disease of the nervous system that affects motor nerve cells (neurons) and results in relentlessly progressive muscle weakness. ALS is inherited (familial) in 5-10% of patients, and the majority have non-inherited (sporadic) ALS. Where Do I Go From Here? Is Stem Cell Therapy Ready? Improving Nutrition / Swallowing. Occupational and Physical Therapy. Guiding Treatment in ALS. Make a Clinic Appointment.
alsresearchcenter.pitt.edu
where_do_we
http://www.alsresearchcenter.pitt.edu/patients/where_do_we.php
Where Do I/We Go From Here? To say the least, ALS is a challenging disease. We will be here to guide you in treatment and in supportive care and directing you in the right direction as far as resources. You will also need the support of family, friends and others who will aid you as needed on a day-to-day basis. We will coordinate your care in our Multidisciplinary Clinic. Although ALS is generally a progressive disease, the progression is usually somewhat predictable and linear and abrupt changes do not.
