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BioInSys: BioInSys

Helmholtz Centre for Infection Research – the new name of the GBF. We focus our attention on bacteria which are either of medical relevance or which serve as models in the analysis of infectious disease. Among the scientific questions we explore are: What turns bacteria into a pathogen? Why are some people highly sensitive and others resistant to infections? How can we intervene in the infection process? Understanding these mechanisms will contribute to combating infectious diseases with new drugs and vacci

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BioInSys: BioInSys | bioinsys.de Reviews
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Helmholtz Centre for Infection Research – the new name of the GBF. We focus our attention on bacteria which are either of medical relevance or which serve as models in the analysis of infectious disease. Among the scientific questions we explore are: What turns bacteria into a pathogen? Why are some people highly sensitive and others resistant to infections? How can we intervene in the infection process? Understanding these mechanisms will contribute to combating infectious diseases with new drugs and vacci
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BioInSys: BioInSys | bioinsys.de Reviews

https://bioinsys.de

Helmholtz Centre for Infection Research – the new name of the GBF. We focus our attention on bacteria which are either of medical relevance or which serve as models in the analysis of infectious disease. Among the scientific questions we explore are: What turns bacteria into a pathogen? Why are some people highly sensitive and others resistant to infections? How can we intervene in the infection process? Understanding these mechanisms will contribute to combating infectious diseases with new drugs and vacci

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1

BioInSys: Workpackges

http://www.bioinsys.de/workpackges

Workpackages of the consortium. WP1 - Sequencing, comparative genomics and data integration (Sun/ Blöcker);. WP2 - Reverse engineering for reconstruction of regulatory network from functional genomic data (Zeng);. WP3 - Integrated and dynamic modeling of networks (Zeng);. WP4 - Dynamic modelling of CSP and quorum sensing (Kremling);. WP5 - Functional genomics and molecular biology of. Modelling experiments (Wagner-Döbler);. WP7 - Proteomic and metabolic analyses (Wang, Zeng);.

2

BioInSys: Site map

http://www.bioinsys.de/metas/site_map

3

BioInSys: Objectives

http://www.bioinsys.de/objectives

Div class=csc-textpic-caption Structure of the consortium: members, their tasks and interactions with each other. /div. The study will be expanded to clinical isolates of Streptococci and to other biofilm forming bacteria important for diseases in the human body. Total synthesis and hypothesis driven chemical modification of Carolacton will be done to optimize the inhibition activity, and to couple it to clinically relevant material, e.g. implants, tubes, and tooth fillings, which will be tes...

4

BioInSys: News & Events

http://www.bioinsys.de/news_events

Project meeting Westerburg. Organizer: Prof. I. Wagner-Döbler, HZI. Project meeting Hamburg. Organizer: Prof. A.-P. Zeng, Technical University Hamburg-Harbug. Project meeting Cuxhaven. Organizer: Dr. Andree Barg, Voco GmbH. MedSys-Koordinatorentreffen, Berlin. Organizer: Prof. Robert Preissner, Charité Berlin. Project meeting at the Technical University München, organizer: Prof. A. Kremling. Evaluation conference BMBF funding priority Medical Systems Biology, Freiburg. November 30 December 1. Animal expe...

5

BioInSys: Publications

http://www.bioinsys.de/publications

Stelzer,M. Sun,Jibin*; Kamphans,T. Fekete,S.P. Zeng,A.P. An extended bioreaction database that significantly improves reconstruction and analysis of genome-scale metabolic networks. Xue,X; Sztajer,H. Buddruhs,N. Petersen,J. Rohde,Manfred*; Talay,S.R. Wagner-Döbler,Irene*;. Lack of the Delta Subunit of. Polymerase Increases Virulence Related Traits of. Lemme,A. Grobe,L. Reck,M. Tomasch,J. Wagner-Döbler,Irene*;. Subpopulation-Specific Transcriptome Analysis of Competence-Stimulating-Peptide-Induced. Inhibi...

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