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Bionucleon

BioNucleon’s research is centered on proprietary oligonucleotide-based ligands for cancer-related targets, with the aim to develop novel anti-cancer therapies with an improved safety profile.

http://www.bionucleon.com/

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BIONUCLEON S.R.L.

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PAGE TITLE
Bionucleon | bionucleon.com Reviews
<META>
DESCRIPTION
BioNucleon’s research is centered on proprietary oligonucleotide-based ligands for cancer-related targets, with the aim to develop novel anti-cancer therapies with an improved safety profile.
<META>
KEYWORDS
1 Eporgen
2 Bionucleon
3 portfolio
4 bioimaging
5 IBB
6 Biostructure
7 BN210
8 Hepatoma
9 HRP-3
10 Enrico Bucci
CONTENT
Page content here
KEYWORDS ON
PAGE
about us,organizational structure,business development,technology and products,hdgf and hrp 3,portfolio,press room,literature,factsheet,portfolio of companies,designed by
CONTENT-TYPE
iso-8859-1
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Bionucleon | bionucleon.com Reviews

https://bionucleon.com

BioNucleon’s research is centered on proprietary oligonucleotide-based ligands for cancer-related targets, with the aim to develop novel anti-cancer therapies with an improved safety profile.

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1

Bionucleon Factsheet

http://www.bionucleon.com/where.asp

BioNucleon S.r.l. Via Ribes, 5. 10010 Colleretto Giacosa (TO). BioNucleon S.r.l. 80121 Naples (NA) Italy. VAT Reg No: 05140231217. Tel 39 0125 561000. Fax 39 0125 538791. E mail: info@bionucleon.com. In a larger map. Bionucleon S.r.l. BioIndustry Park Silvano Fumero. Via Ribes 5, 10010 Colleretto Giacosa (TO).

2

Bionucleon Business Development

http://www.bionucleon.com/business.asp

BioNucleon s mission is to advance its innovative lead compound BN210 to a pre-clinical proof of concept in neuroblastoma (an orphan indication) and then seek partnership with an oncology franchise for the future development of BN210 and of other compounds from the class. BioNucleon is open to various ways of partnership that include:. Financing of the preclinical regulatory studies with BN210 towards an IND and of a Phase I study in patients with neuroblastoma. Bionucleon S.r.l.

3

About BioNucleon S.r.l.

http://www.bionucleon.com/structure.asp

Project Director at Eporgen. Scientific Director at Eporgen. Bionucleon S.r.l. BioIndustry Park Silvano Fumero. Via Ribes 5, 10010 Colleretto Giacosa (TO).

4

Bionucleon Portfolio

http://www.bionucleon.com/Portfolio.asp

Bionucleon developed a bioinformatic tool for the identification of oligonucleotide-based ligands and combined it with rational design. BioNucleon s oligonucleotide ligands are designed to bind extracellular proteins and target the N-terminal PWWP domain of the HDGF family, which is able to bind to nucleic acids. Bionucleon S.r.l. BioIndustry Park Silvano Fumero. Via Ribes 5, 10010 Colleretto Giacosa (TO).

5

About BioNucleon S.r.l.

http://www.bionucleon.com/about.asp

BioNucleon was founded in June 2005 by Enrico Bucci, Roberto Sapio and Margherita Valente. It has been incubated by Eporgen Venture in the Silvano Fumero Bioindustry Park. Close to Ivrea in the Piedmont region of Italy, while its registered office was kept in Naples. BioNucleon won the Best Young and Innovative Italian Company award of Unioncamere (Association of Italian Chambers of Commerce) in 2006. Bionucleon S.r.l. BioIndustry Park Silvano Fumero. Via Ribes 5, 10010 Colleretto Giacosa (TO).

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BioNucleon

http://www.eporgen.com/aziende/bionucleon.asp

Originated from the Istituto di Biostrutture e Bioimmagini (IBB), National Research Council, Napoli; established in 2005, it operates in the field of anti-cancer drug discovery. BioNucleon s lead candidate, BN210, is a pegylated aptamer which targets the N-terminal PWWP domain shared by all the Hepatoma Derived Growth Factors (HDGF), blocks the factors activity and inhibits angiogenesis. Potential applications include neuroblastoma, NSCLC and hepatoma. Two patents filed in 2005 and 2008.

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