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Biotranex - your partner to release full potential of pharmaceutical R&D

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Biotranex - your partner to release full potential of pharmaceutical R&D
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Biotranex - your partner to release full potential of pharmaceutical R&D

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1

Integrated Drug Discovery Services

http://www.biotranex.com/portal/index.php/bt-service/discovery-support

Absorption and Transporter Service. Bioreactors / Metabolite Synthesis. Consulting on IND and NDA Filing. Integrated Drug Discovery Services. Biotranex offers integrated drug discovery services including:. Medicinal chemistry: lead optimization. Biology: assay development, screening, disease models. Pharmaceutics: solubility and permeability. Toxicology: cytotoxicity, hERG, Ames, chemical toxicity, telemetry. Efflux and uptake transpoters. Caco-2 and transfected cells.

2

Consulting on IND and NDA Filing

http://www.biotranex.com/portal/index.php/bt-service/consulting-on-ind-and-nda-filing

Absorption and Transporter Service. Bioreactors / Metabolite Synthesis. Consulting on IND and NDA Filing. Consulting on IND and NDA Filing. Biotranex provides consulting services for IND and NDA filings:. Conduct necessary studies to meet regulatory requirements. Help to formulate an IND/NDA filing strategy. Prepare reports and the regulatory filing documents. Serve as the subject matter expert. Efflux and uptake transpoters. Caco-2 and transfected cells.

3

Analytical Supports

http://www.biotranex.com/portal/index.php/bt-service/analytical

Absorption and Transporter Service. Bioreactors / Metabolite Synthesis. Consulting on IND and NDA Filing. Biotranex provides method development and sample analysis services for structural identification and quantification of pharmaceuticals, nutraceuticals, agrochemicals, and specialty chemicals in various matrices such as API, in vitro incubations, plasma, tissues, and environmental samples:. Quantification of small molecules in plasma, urine, bile, tissue extract of animal species and human subjects.

4

ADME/PK Service Overview

http://www.biotranex.com/portal/index.php/bt-service

Absorption and Transporter Service. Bioreactors / Metabolite Synthesis. Consulting on IND and NDA Filing. Our services cover a broad spectrum of ADME, pharmacokinetic and toxicity studies. We tailor our capabilities to meet client’s needs. We partner with clients to address DMPK/toxicity issues, and to develop strategies to reduce attrition rate. We commit ourselves to offer the best services for our clients. Integrated Drug Discovery Services. Consulting on IND/NDA Filings. Efflux and uptake transpoters.

5

Drug Metabolism / Chemical Toxicology

http://www.biotranex.com/portal/index.php/bt-service/bt-dm

Absorption and Transporter Service. Bioreactors / Metabolite Synthesis. Consulting on IND and NDA Filing. Drug Metabolism / Chemical Toxicology. Biotranex provides laboratory services for a comprehensive list of metabolism/chemical toxicology studies including:. Metabolite profiling using LC/UV, LC/MS/MS, and LC/radiodetection. Structural identification of metabolites. Reaction phenotyping studies for CYP, UGT, SULT, aldehyde oxidase and hydrolytic enzymes, and determination of K.

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