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ALS Today Magazine | ALS Therapy Development Institute

ALS Today is an online newsmagazine dedicated to reporting current and emerging bench and clinical drug development theme in the field of ALS (Motor Neuron Disease).

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ALS Today Magazine | ALS Therapy Development Institute | blogs.als.net Reviews
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ALS Today Magazine | ALS Therapy Development Institute | blogs.als.net Reviews

https://blogs.als.net

ALS Today is an online newsmagazine dedicated to reporting current and emerging bench and clinical drug development theme in the field of ALS (Motor Neuron Disease).

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1

All posts by mpflumm | ALS Therapy Development Institute

http://blogs.als.net/author/mpflumm.aspx

Michelle Pflumm, Ph.D. June 21, 2014. As many as 1 out of 5 cases of familial ALS are caused by mutations (red) in the enzyme superoxide dismutase 1 (SOD1). SOD1) is a key enzyme that helps keep our motor nerves healthy by detoxifying them. But in at least some people with ALS. These enzymes misfold- contributing to the disease. Researchers remain unsure how misfolded SOD1 contributes to ALS. But according to studies led by University of British Columbia's Neil Cashman MD. Are beginning to emerge. Misfol...

2

In The Pipeline | ALS Therapy Development Institute

http://blogs.als.net/category/In-The-Pipeline.aspx

120 PALS to Enroll in Retigabine Trial. Robert A. Goldstein. April 21, 2015. A group of collaborators announced. Their intent to launch a clinical trial in 12 academic sites on the anti-epileptic drug, Retigabine. At the end of 2014, during a scientific meeting in Brussels, Kevin Eggan, Ph.D., who led the team doing the preclinical research behind the selection of this drug, reported that the trial will enroll up to 120 people. And the ALS Association. The Retigabine trial is NOT currently enrolling PALS...

3

Podcast | ALS Therapy Development Institute

http://blogs.als.net/category/Podcast.aspx

Charting the course of ALS. Michelle Pflumm, Ph.D. January 31, 2014. Follow the TDP-43 Road. The spread of key proteins (red) between neurons in the brain and the spinal cord may in part explain the regional progression of the disease. Adapted from Braak, H. 2013) Courtesy of Nature Publishing Group. Occurs due to a progressive loss of motor neurons – the cells that enable muscles to move. One arm or leg may often. Aims to retrace the ‘steps’ of ALS by tracking TDP-43. Now, the US-German team reports.

4

From The Bench | ALS Therapy Development Institute

http://blogs.als.net/category/From-The-Bench.aspx

Newron Announces Phase 2 Clinical Trial of sNN0029 (VEGF). Robert A. Goldstein. January 27, 2015. Earlier this month, Newron Pharmaceuticals announced. That it would soon execute a Phase 2 clinical trial of its VEGF treatment known as sNN0029. The announcement comes. Shortly after one of the lead investigators, Philip Van Damme, PhD, reported the results of the Phase 1 clinical trial. Which provides email updates upon subscription. Earlier preclinical studies conducted in SOD1 rats with the compound ,.

5

Postcards | ALS Therapy Development Institute

http://blogs.als.net/category/Postcards.aspx

Neuralstem Phase 2 Clinical Trial Results Annouced. Robert A. Goldstein. March 13, 2015. Neuralstem recently announced via press release. Results from a Phase 2 clinical trial of their fetal-derived stem cell treatment, NSI-566. Also reported similar results regarding safety. A positive change in grip strength tests. No further details were provided about this cohort, which they term the responder group. The other half of the patients in the trial, termed the nonresponder group, saw a negative ch...A neg...

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augiesquest.org augiesquest.org

About | Augie's Quest

http://www.augiesquest.org/about

Stay connected with Augie. Stay connected with Augie. Chairman of the Board of Directors, ALS TDI. Augie Nieto is the co-founder of Life Fitness, a global leader in the fitness industry. He was one of the original pioneers in the fitness industry and was president of Life Fitness for nearly 25 years until they were acquired by Brunswick Corporation in 1997. Augie lives in Corona del Mar, California with his wife Lynne and dog Rubye. They have four adult, married children and five grand babies. Lynne co f...

augiesquest.org augiesquest.org

FAQ | Augie's Quest

http://www.augiesquest.org/faq

Stay connected with Augie. Stay connected with Augie. What is Augie’s Quest? The purpose of Augie's Quest has always been to fund research and drug development aimed at ending ALS. Lou Gehrig's disease. Since 2007, Augie's Quest has raised over $45 million in support of finding effective ALS treatments. This makes Augie's Quest the largest individual fundraising program for ALS! How are ALS TDI and Augie's Quest connected? Who is Augie Nieto? What has Augie's Quest help ALS TDI accomplish? Screened dozen...

augiesquest.org augiesquest.org

Photos | Augie's Quest

http://www.augiesquest.org/photos

Stay connected with Augie. Stay connected with Augie. Photos from the Tradition Of Hope Gala 2013. Photos from the Tradition Of Hope Gala 2010. Photos from the Augie's Quest Bash 2010. Photos from the Tradition of Hope Gala 2009. Photos from the Champions of Hope 2009. 2015 Augie's Quest Bash. Photos from the 2015 Augie's Quest Bash. Tradition of Hope 2014. Photos from the Tradition of Hope 2014. 2014 Augie's Quest Bash. Photos from the 2014 Augie's Quest Bash. 2013 Augie's Quest Bash. Augie's Quest Blac...

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Videos | Augie's Quest

http://www.augiesquest.org/videos

Stay connected with Augie. Stay connected with Augie. Nancy O'Dell attends 2015 Tradition of Hope. Orange County Man Uses his 'Empire' To Fight ALS. CNN Augie Nieto’s Story. Exploring the science behind the cause and the cure). Zumba-United We Dance to Cure ALS. MDA Show of Strength 2012. Augie’s Quest BASH 2011 video. Ty Hendron featuring former NFL player and current ALS patient Kevin Turner. Augie on Telethon 2010 (focus on MDA's ALS Research Initiative). Augie’s Quest BASH 2010. March 30, 2009. 2007 ...

augiesquest.org augiesquest.org

Friends of the Quest | Augie's Quest

http://www.augiesquest.org/friends-of-the-quest

Stay connected with Augie. Stay connected with Augie. Friends of the Quest. Augie's Quest lost a champion in the fight against ALS. Moosa Malek was a generous supporter of Augie's Quest and the ALS Therapy Development Institute. Moosa Malek will be missed and remembered forever by Augie's Quest, among many others. What Kind of World Do You Want. The site whatkindofworlddoyouwant.com is the property of John Ondrasik and is administrated by John and the Five For Fighting management team. Augie's Other Job:...

augiesquest.org augiesquest.org

Calendar | Augie's Quest

http://www.augiesquest.org/calendar

Stay connected with Augie. Stay connected with Augie. Mile High Bash - September 17, 2016. 11th Annual Bash for AQ - Wednesday, March 23rd in Orlando, FL. Big Canyon Golf Tournament and Wine Event - Thursday April 21st in Newport Beach, CA. Calling All Angel's Golf Classic - Monday, August 8th in Seattle, WA. Team Quest 1/2 Marathon - Saturday, October 8th in Brooklyn, NY. Tradition of Hope Gala - Saturday, October 15th in Los Angeles, CA. Like Augie Nieto, 'Gleason' Shows Champion of ALS. A Record-Break...

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ALS Today Magazine | ALS Therapy Development Institute

120 PALS to Enroll in Retigabine Trial. Categories: In The Pipeline. Posted By Robert A. Goldstein. April 21, 2015. A group of collaborators announced their intent to launch a clinical trial in 12 academic sites on the anti-epileptic drug, Retigabine, in people diagnosed with ALS. Neuralstem Phase 2 Clinical Trial Results Annouced. Posted By Robert A. Goldstein. March 13, 2015. Newron Announces Phase 2 Clinical Trial of sNN0029 (VEGF). Categories: From The Bench. Posted By Robert A. Goldstein. It was rec...

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Young Black Boys Are Committing Suicide at Rates Higher Than Ever. WATCH: Letterman Gets a Send Off From U.S. Presidents Current, Former and Deceased. One Month Later, Exposing Baltimore Police Lies In the Death of Freddie Gray. Janice Dickinson is Suing Bill Cosby for Defamation. Thu, 05/21/2015 - 08:25. 9 Types of News Headlines That Reveal the Madness of Our Times. Wed, 05/20/2015 - 13:39. The Clintons Made Wall Street Richer, and It Returned the Favor. Wed, 05/20/2015 - 07:05. Wed, 05/20/2015 - 07:21.

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