btb.uhnres.utoronto.ca

BTB Domain Database

This database catalogs BTB proteins found in 17 fully sequenced eukaryotic genomes. This database was the source for the analysis presented in the artcile "Sequence and structural analysis of BTB proteins." Stogios PJ, Downs GS, Jauhal J, Nandra S and Privé GG, Genome Biology. Protein sequences and annotation information can be retrieved by searching by keywords or protein architecture. Searching by gene or protein names, alternate names, or domain content), search by BTB ID. IPR005820,M channel nlg.

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BTB Domain Database | btb.uhnres.utoronto.ca Reviews

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This database catalogs BTB proteins found in 17 fully sequenced eukaryotic genomes. This database was the source for the analysis presented in the artcile Sequence and structural analysis of BTB proteins. Stogios PJ, Downs GS, Jauhal J, Nandra S and Priv&eacute GG, Genome Biology. Protein sequences and annotation information can be retrieved by searching by keywords or protein architecture. Searching by gene or protein names, alternate names, or domain content), search by BTB ID. IPR005820,M channel nlg.

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1 btb database home

2 btb database statistics

3 btb domain analysis

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6 btb domain database

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8 160ensembl gene id

9 search species

10 all species

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BTB Domain Database | btb.uhnres.utoronto.ca Reviews

https://btb.uhnres.utoronto.ca

This database catalogs BTB proteins found in 17 fully sequenced eukaryotic genomes. This database was the source for the analysis presented in the artcile "Sequence and structural analysis of BTB proteins." Stogios PJ, Downs GS, Jauhal J, Nandra S and Priv&eacute GG, Genome Biology. Protein sequences and annotation information can be retrieved by searching by keywords or protein architecture. Searching by gene or protein names, alternate names, or domain content), search by BTB ID. IPR005820,M channel nlg.

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btb.uhnres.utoronto.ca

1

Panel of HMM's describing the families of BTB proteins

http://btb.uhnres.utoronto.ca/hmms.html

Panel of HMM's describing the families of BTB proteins. BTB domains were identified using this collection of profile HMMs, generated by HMMER 2.3.2, that were trained on families of BTB proteins. These families were defined on the basis of sequence similarity, secondary structure content, and domain architecture of the full-length proteins. These HMMs allow detection of remote homologs of BTB domains and accurate alignment of the BTB domain. These steps were taken in the generation of all HMM's:. 7 Gener...

2

BTB Domain Database

http://btb.uhnres.utoronto.ca/blast_defaults.html

The following parameters are used for all BLAST searches and cannot be altered (set by the defaults at NCBI):. Gap costs: existence=11, extension=1.

3

BTB Domain Database

http://btb.uhnres.utoronto.ca/index.html

This database catalogs BTB proteins found in 17 fully sequenced eukaryotic genomes. This database was the source for the analysis presented in the artcile "Sequence and structural analysis of BTB proteins." Stogios PJ, Downs GS, Jauhal J, Nandra S and Priv&eacute GG, Genome Biology. Protein sequences and annotation information can be retrieved by searching by keywords or protein architecture. Searching by gene or protein names, alternate names, or domain content), search by BTB ID. IPR005820,M channel nlg.

4

Database Statistics

http://btb.uhnres.utoronto.ca/db_stats.php

Representation of Main BTB Partner Domains in All Species. Number of BTB proteins. Total number of different species: 17. Total number of BTB proteins : 2278. Last updated on August 21, 2016. Back to BTB Database Query.

5

BTB Domain Database Construction

http://btb.uhnres.utoronto.ca/db_construction.html

Construction of the BTB domain database. Why build a separate database for this domain? This database represents a truly non-redundant set of BTB protein sequences in 17 fully sequenced genomes. Databases such as SMART, PFAM and COG contain redundant sequence composition (fragments of proteins, duplicate protein sequences). A truly non-redundant set of protein sequences is necessary for genome-wide analysis that is not skewed by database composition. Construction of HMM's and sequence searches:. Hmmsearc...

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privelab.uhnresearch.ca

Projects

http://privelab.uhnresearch.ca/projects

The Privé Lab. Protein Structure and Function. Transcriptional regulation complexes are large, multicomponent assemblies involving proteins with various enzymatic activities, adaptor functions and DNA recognition modules. We are looking at interplay between the components of these assemblies in order to understand the structural “logic” of how these complexes carry out intricate biological activities. Link to BTB website. Link to BACK website. Assembly and function of ubiquitin ligase E3 complexes. E2 pr...

cooley.medicine.yale.edu

Links > Cooley Lab | Genetics | Yale School of Medicine

http://cooley.medicine.yale.edu/links

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btb.uhnres.utoronto.ca

BTB Domain Database

This database catalogs BTB proteins found in 17 fully sequenced eukaryotic genomes. This database was the source for the analysis presented in the artcile "Sequence and structural analysis of BTB proteins." Stogios PJ, Downs GS, Jauhal J, Nandra S and Priv&eacute GG, Genome Biology. Protein sequences and annotation information can be retrieved by searching by keywords or protein architecture. Searching by gene or protein names, alternate names, or domain content), search by BTB ID. IPR005820,M channel nlg.

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