cancerinitiation.com

Cancer Initiation

Science Education meets Cancer Research. Saturday, April 25, 2015. The principles of epigenetics imply a lack of equivalence between mutagenicity and carcinogenesis. This quantified assessment of a compounds mutagenicity, or ability to interfere with the proper replication of DNA is a priory assumed to be equivalent to its carcinogenic risk. This causal-equivalence presumably arises from early work in genetics, primarily in fruit flies ( drosophila ) . As a "literature experiment", I first placed the ter...

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Cancer Initiation | cancerinitiation.com Reviews

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Science Education meets Cancer Research. Saturday, April 25, 2015. The principles of epigenetics imply a lack of equivalence between mutagenicity and carcinogenesis. This quantified assessment of a compounds mutagenicity, or ability to interfere with the proper replication of DNA is a priory assumed to be equivalent to its carcinogenic risk. This causal-equivalence presumably arises from early work in genetics, primarily in fruit flies ( drosophila ) . As a literature experiment, I first placed the ter...

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Cancer Initiation | cancerinitiation.com Reviews

https://cancerinitiation.com

Science Education meets Cancer Research. Saturday, April 25, 2015. The principles of epigenetics imply a lack of equivalence between mutagenicity and carcinogenesis. This quantified assessment of a compounds mutagenicity, or ability to interfere with the proper replication of DNA is a priory assumed to be equivalent to its carcinogenic risk. This causal-equivalence presumably arises from early work in genetics, primarily in fruit flies ( drosophila ) . As a "literature experiment", I first placed the ter...

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Cancer Initiation: Glycosylation patterns of extra-cellular matrix proteins as fossils of an earlier metabolic state

http://www.cancerinitiation.com/2013/12/glycosylation-patterns-of-extra.html

Science Education meets Cancer Research. Sunday, December 22, 2013. Glycosylation patterns of extra-cellular matrix proteins as fossils of an earlier metabolic state. As mentioned in the previous post, regarding the loss of expression and predicted function of PKD 1. Two somewhat well known enzymes, at least to students who have taken a biology course in which ATP production has been discussed , are NAD and FAD. Bore more similarity to nucleotides than proteins, and they were necessary for their respecti...

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Cancer Initiation: Micro RNAs that regulate cell cycle check point components are implicated in loss of control of the cell cycle in glioblastoma

http://www.cancerinitiation.com/2014/01/micro-rnas-that-regulate-cell-cycle.html

Science Education meets Cancer Research. Thursday, January 23, 2014. Micro RNAs that regulate cell cycle check point components are implicated in loss of control of the cell cycle in glioblastoma. So, precisely where is the mechanism that fails and sends the cell back into the cell cycle? When we use the term checkpoint. We most correctly are referring to these molecular mechanisms that work at the G1 to S. Transition, where (of course ) the four phases of the cell cycle are G1. And Mitosis ( M. CDK) A k...

3

Cancer Initiation: Kidney cysts are shown to arise from an epigenetic "second hit"

http://www.cancerinitiation.com/2013/12/kidney-cysts-are-shown-to-arise-from.html

Science Education meets Cancer Research. Wednesday, December 18, 2013. Kidney cysts are shown to arise from an epigenetic "second hit". Autosomal Dominant Polycystic Kidney Disease has always been observed to be an inherited disorder. But, as the name implies, there has always been a puzzle as to the nature of onset of kidney cysts. Epigenetic modifications are numerous, but the primary method, and easiest to detect using laboratory methods is called changes to DNA methylation. Methylation applies to...

4

Cancer Initiation: The danger of misrepresentation of scientific studies is demonstrated by "The Scientist" article on vitamin deficiency

http://www.cancerinitiation.com/2014/01/the-danger-of-misrepresentation-of.html

Science Education meets Cancer Research. Thursday, January 30, 2014. The danger of misrepresentation of scientific studies is demonstrated by "The Scientist" article on vitamin deficiency. The immune system is divided into the innate. Division and the adaptive. Division. When we study the acquired immunity that we receive from environmental exposure, as well a immunization from vaccines, we are speaking of the adaptive. The title chosen by The Scientist was as follows:. Vitamin A deficiency is associated...

5

Cancer Initiation: Bone Marrow Stem Cells Provide a micro-environment that evades the immune system

http://www.cancerinitiation.com/2013/02/bone-marrow-stem-cells-provide-micro.html

Science Education meets Cancer Research. Thursday, February 21, 2013. Bone Marrow Stem Cells Provide a micro-environment that evades the immune system. The significance of "Das" is that the mechanism of "DeGiorgi" has not been elucidated. With Das, we can now hypothesize that the observatons and correlatons in De Giorgi are due to protection from the normal operation of the immune system in the micro-environment of bone marrow, particularly in association with CD271 positive hematopoetic stem cells.

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Cancer Initiation

Science Education meets Cancer Research. Saturday, April 25, 2015. The principles of epigenetics imply a lack of equivalence between mutagenicity and carcinogenesis. This quantified assessment of a compounds mutagenicity, or ability to interfere with the proper replication of DNA is a priory assumed to be equivalent to its carcinogenic risk. This causal-equivalence presumably arises from early work in genetics, primarily in fruit flies ( drosophila ) . As a "literature experiment", I first placed the ter...

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