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Gaucher Group Research
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Directed Evolution - REAP ( click for schematic. Directed evolution and protein engineering often utilize sequence information contained within homologs to guide the design of diverse libraries. Combinatorially capturing this information can require the production of 10. Reconstruction and resurrection of ancient sequences. Engineering proteins composed of unnatural amino acids. The ancestral reconstruction field would no longer be confined to single gene analysis. It is also quite possible that our ...
drugdelivery.chbe.gatech.edu
Laboratory for Drug Delivery - Patents
http://drugdelivery.chbe.gatech.edu/patents.html
Laboratory for Drug Delivery. Prof Mark R. Prausnitz. Georgia Institute of Technology. MR Prausnitz, MG Allen, JH Park, YK Yoon, and JW Park (Issued 2015) Methods and devices for thermal treatment , US patent 8,690,865. MR Prausnitz, HF Edelhauser, and SR Patel (Issued 2014) Methods and devices for drug delivery to ocular tissue using microneedles, US patent 8,808,225. HS Gill and MR Prausnitz (Issued 2013) Coated microstructures and method of manufacture thereof, Canadian patent 2,612,005. MR Prausnitz,...
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Laboratory for Drug Delivery - Home
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Laboratory for Drug Delivery. Prof Mark R. Prausnitz. Georgia Institute of Technology. If you are interested in applying for a position in our research group, please contact us as described below. While we do not have any specific positions available right now, we are always interested to know about excellent postdoctoral candidates for possible future openings. If you are interested, please email Dr. Mark Prausnitz. Indicating your areas of interest along with a copy of your CV. In the subject line.
drugdelivery.chbe.gatech.edu
Laboratory for Drug Delivery - Publications
http://drugdelivery.chbe.gatech.edu/publications.html
Laboratory for Drug Delivery. Prof Mark R. Prausnitz. Georgia Institute of Technology. MJ Mistilis, JC Joyce, ES Esser, I Skountzou, RW Compans, AS Bommarius, MR Prausnitz, Long-term stability of influenza vaccine in a dissolving microneedle patch, Drug Delivery and Translational Research. P Chakravarty, CD Lane, TM Orlando, MR Prausnitz, Parameters affecting intracellular delivery of molecules using laser-activated carbon nanoparticles, Nanomedicine. 228:48-57. [PubMed link]. 234:1-9. [PubMed link].
drugdelivery.chbe.gatech.edu
Laboratory for Drug Delivery - Members
http://drugdelivery.chbe.gatech.edu/members.html
Laboratory for Drug Delivery. Prof Mark R. Prausnitz. Georgia Institute of Technology. Mark R. Prausnitz. J Erskine Love Chair in Chemical and. PhD Massachusetts Institute of Technology. Program and Operations Manager. BS: State University of New York at Binghamton. Intracellular drug delivery via laser-activated nanoparticles. BS: University of Florida. BS: Massachusetts Institute of Technology. Microneedle patches for the delivery of measles/rubella and influenza vaccines. BS: Wichita State University.
drugdelivery.chbe.gatech.edu
Laboratory for Drug Delivery - Galleries
http://drugdelivery.chbe.gatech.edu/gallery_index.html
Laboratory for Drug Delivery. Prof Mark R. Prausnitz. Georgia Institute of Technology. Below are links to image galleries from the laboratory. Click on an image to download a full-resolution image. Please list photo credits. Georgia Institute of Technology. Center for Drug Design, Development. GT Institute for Bioengineering and Biosciences. GT School of Chemical and Biomolecular Engineering. 2010 Alyeska Theme. Web Design and Development by Jason Bobich.
drugdelivery.chbe.gatech.edu
Laboratory for Drug Delivery - Home
http://drugdelivery.chbe.gatech.edu/index.html
Laboratory for Drug Delivery. Prof Mark R. Prausnitz. Georgia Institute of Technology. Welcome to the Laboratory for Drug Delivery! Dr Prausnitz and his colleagues carry out research on biophysical methods of drug delivery, which employ microneedles, ultrasound, lasers, electric fields, heat, convective forces and other physical means to control the transport of drugs, proteins, genes and vaccines into and within the body. The Centers for Disease Control and Prevention. Dr Prausnitz and colleagues also s...
drugdelivery.chbe.gatech.edu
Laboratory for Drug Delivery - Microneedle Gallery
http://drugdelivery.chbe.gatech.edu/gallery_microneedles.html
Laboratory for Drug Delivery. Prof Mark R. Prausnitz. Georgia Institute of Technology. A dissolving microneedle patch encapsulating a model vaccine (colored pink). Each microneedle is 700 μm tall. (Credit: Devin McAllister, Georgia Tech). A microneedle patch being applied to the arm. (Credit: Rob Felt Georgia Tech). A microneedle patch being applied to the arm. (Credit: Rob Felt Georgia Tech). A patch containing 36 dissolving microneedles is shown on a fingertip. The microneedles dissolve wihin minut...
drugdelivery.chbe.gatech.edu
Laboratory for Drug Delivery - Cellular Gallery
http://drugdelivery.chbe.gatech.edu/gallery_intracellular.html
Laboratory for Drug Delivery. Prof Mark R. Prausnitz. Georgia Institute of Technology. Intracellular Delivery Image Gallery. A field of human prostate cancer cells after exposure to laser-activated carbon nanoparticles. The many green cells have taken up a model therapeutic compound, calcein, while the few red-stained cells are dead. Each of the green or red spots is a single cell. (Credit: Prerona Chakravarty, Georgia Tech). Georgia Institute of Technology. Center for Drug Design, Development. School of...
drugdelivery.chbe.gatech.edu
Laboratory for Drug Delivery - People Gallery
http://drugdelivery.chbe.gatech.edu/gallery_people.html
Laboratory for Drug Delivery. Prof Mark R. Prausnitz. Georgia Institute of Technology. Professor Mark Prausnitz, headshot (Credit: Rob Felt Georgia Tech). Professor Mark Prausnitz, headshot (Credit: Rob Felt Georgia Tech). Researchers pose with an image of an array of stainless steel microneedles. Shown, left-to-right, are Marcus Collins of the CDC, Chris Edens of Georgia Tech, Paul Rota of the CDC and Mark Prausnitz of Georgia Tech. (Georgia Tech Photo: Gary Meek). Researchers Mark Prausnitz (left) of G...