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Channelpedia

Logged in as a Visitor. Channelpedia is an information management framework for comprehensive ion channel information. It is a knowledge base system centered on genetically expressed ion channel models and it encourages researchers of the field to contribute, build and refine the information through an interactive wiki-like interface. It is web-based, freely accessible and currently contains 187 annotated ion channels with 50 Hodgkin-Huxley models. HH models from literature. Building models for each ion ...

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Channelpedia | channelpedia.epfl.ch Reviews
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Logged in as a Visitor. Channelpedia is an information management framework for comprehensive ion channel information. It is a knowledge base system centered on genetically expressed ion channel models and it encourages researchers of the field to contribute, build and refine the information through an interactive wiki-like interface. It is web-based, freely accessible and currently contains 187 annotated ion channels with 50 Hodgkin-Huxley models. HH models from literature. Building models for each ion ...
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Channelpedia | channelpedia.epfl.ch Reviews

https://channelpedia.epfl.ch

Logged in as a Visitor. Channelpedia is an information management framework for comprehensive ion channel information. It is a knowledge base system centered on genetically expressed ion channel models and it encourages researchers of the field to contribute, build and refine the information through an interactive wiki-like interface. It is web-based, freely accessible and currently contains 187 annotated ion channels with 50 Hodgkin-Huxley models. HH models from literature. Building models for each ion ...

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channelpedia.epfl.ch channelpedia.epfl.ch
1

Channelpedia

http://channelpedia.epfl.ch/cell/2

Logged in as a Visitor. Human Embryonic Kidney 293 Cells. Kir, Delayed rectifier, KCNE1, Nav1.7, traces of Nav1.2, Nav1.3 and Nav1.5 , Cav1.2, Cav1.3, IA, HCN2, HCN3. He B et al. Human embryonic kidney (HEK293) cells express endogenous voltage-gated sodium currents and Na v 1.7 sodium channels. Neurosci. Lett., 2010 Jan 22 , 469 (268-72). Kurejová M. et al. Changes in ultrastructure and endogenous ionic channels activity during culture of HEK 293 cell line. Eur J Pharmacol., 2007 Jul 12 , 567 (10-8).

2

Channelpedia

http://channelpedia.epfl.ch/lreferences

Logged in as a Visitor. Published literature related to all the listed ion channels in Channelpedia can be found here. They are classified under the relevant ion channels and can be accessed by clicking on the link to the channels on the left sidebar. C) 2010-2016 running Channelpedia rev. 214:291M.

3

Channelpedia

http://channelpedia.epfl.ch/ionchannels/fitting

Logged in as a Visitor. Hodgkin Huxley models from literature. Typical parameters required to build a HH model are, applied stimulus protocol, reversal potential of an ion channel along with steady state activation and inactivation kinetics. Following figure lists these parameters for Kv3.3 ion channel from a published article (Desai et al., 2008) [1]. After digitization and curve fitting, GenericFit a custom built Matlab routine is used to simulate the ion channel kinetics. GenericFit provides graph...

4

Channelpedia

http://channelpedia.epfl.ch/cell/1

Logged in as a Visitor. Chinese Hamster Ovary Cells. CHO cells are a line of epithelial-like cells that was initiated in 1957 by T.T. Puck and colleagues at the Department of Biophysics, University of Colorado Medical School in Denver, USA from a biopsy of an ovary of an adult Chinese hamster [1352]. TRPM4, KCNK5, Kir, Neglegible Ik. PUCK T. et al. Genetics of somatic mammalian cells. III. Long-term cultivation of euploid cells from human and animal subjects. J Exp Med., 1958 Dec 1 , 108 (945-56).

5

Channelpedia

http://channelpedia.epfl.ch/ionchannels

Logged in as a Visitor. Channelpedia is an information management framework for comprehensive ion channel information. It is a knowledge base system centered on genetically expressed ion channel models and it encourages researchers of the field to contribute, build and refine the information through an interactive wiki-like interface. It is web-based, freely accessible and currently contains 187 annotated ion channels with 50 Hodgkin-Huxley models. HH models from literature. Building models for each ion ...

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Logged in as a Visitor. Channelpedia is an information management framework for comprehensive ion channel information. It is a knowledge base system centered on genetically expressed ion channel models and it encourages researchers of the field to contribute, build and refine the information through an interactive wiki-like interface. It is web-based, freely accessible and currently contains 187 annotated ion channels with 50 Hodgkin-Huxley models. HH models from literature. Building models for each ion ...

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