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The Cheung Lab

The Cheung Lab - specializing in chromatin and epigenetics research. Signaling and epigenetic regulation of gene expression through chromatin modification. Welcome to Peter Cheung's Lab web page! The nucleus of a murine fibroblast expressing H2A.Z-GFP. Metaphase chromosomes stained for DNA (blue), histone H2A.Z (red), histone H3-triMeK27 (green). Research Interests and Goals. In particular, we focus on histone phosphorylation. Website created by: Elizabeth and Christopher Lord.

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The Cheung Lab | chromatintoronto.ca Reviews
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The Cheung Lab - specializing in chromatin and epigenetics research. Signaling and epigenetic regulation of gene expression through chromatin modification. Welcome to Peter Cheung's Lab web page! The nucleus of a murine fibroblast expressing H2A.Z-GFP. Metaphase chromosomes stained for DNA (blue), histone H2A.Z (red), histone H3-triMeK27 (green). Research Interests and Goals. In particular, we focus on histone phosphorylation. Website created by: Elizabeth and Christopher Lord.
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2 members
3 publications
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5 lab members
6 methylation
7 and ubiquitylation
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The Cheung Lab | chromatintoronto.ca Reviews

https://chromatintoronto.ca

The Cheung Lab - specializing in chromatin and epigenetics research. Signaling and epigenetic regulation of gene expression through chromatin modification. Welcome to Peter Cheung's Lab web page! The nucleus of a murine fibroblast expressing H2A.Z-GFP. Metaphase chromosomes stained for DNA (blue), histone H2A.Z (red), histone H3-triMeK27 (green). Research Interests and Goals. In particular, we focus on histone phosphorylation. Website created by: Elizabeth and Christopher Lord.

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chromatintoronto.ca chromatintoronto.ca
1

The Cheung Lab — Links

http://www.chromatintoronto.ca/links.html

Department of Medical Biophysics. Peter's Medical Biophysics profile page. Peter's OCI profile page. Peter's CRC profile page. Chromatin Structure and Function. Jakob Waterborg's chromatin page. National Cancer Institute of Canada (NCIC). Canadian Institutes for Health Research (CIHR). Canada Research Chairs (CRC). National Center for Biotechnology Information (NCBI).

2

The Cheung Lab — Publications

http://www.chromatintoronto.ca/publications.html

Histone phosphorylation: chromatin modifications that link cell signaling pathways to nuclear function regulation. Lau, P. and Cheung, P. (Book Chapter) The Handbook of Cell Signaling. In press. Monoubiquitylation of H2A.Z distinguishes its association with euchromatin or facultative heterochromatin. Sarcinella, E., Zuzarte, P.C., Lau, P.N., Draker, R. and Cheung, P. Mol Cell Biol. 2007 Sep;27(18):6457-68. Chromatin immunoprecipitation assay for mammalian tissues. Cheung W.L., Ajiro K., Samej...Boggs, B&...

3

The Cheung Lab

http://www.chromatintoronto.ca/index.html

The Cheung Lab - specializing in chromatin and epigenetics research. Signaling and epigenetic regulation of gene expression through chromatin modification. Welcome to Peter Cheung's Lab web page! The nucleus of a murine fibroblast expressing H2A.Z-GFP. Metaphase chromosomes stained for DNA (blue), histone H2A.Z (red), histone H3-triMeK27 (green). Research Interests and Goals. In particular, we focus on histone phosphorylation. Website created by: Elizabeth and Christopher Lord.

4

The Cheung Lab — Projects

http://www.chromatintoronto.ca/projects.html

Cancer is often caused by dysregulated expression of oncogenes or tumour suppressor genes. Post-translational modifications of histone proteins is one of the fundamental mechanisms that regulates gene expression. In the context of the human genome, DNA is complexed with histone proteins to form nucleosomes and chromatin (Figure 1). This functional organization of the genome is tightly regulated to ensure the appropriate gene expression patterns. We have two main questions:. In the activation of immediate...

5

The Cheung Lab — Lab Members

http://www.chromatintoronto.ca/lab_members.html

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The Cheung Lab - specializing in chromatin and epigenetics research. Signaling and epigenetic regulation of gene expression through chromatin modification. Welcome to Peter Cheung's Lab web page! The nucleus of a murine fibroblast expressing H2A.Z-GFP. Metaphase chromosomes stained for DNA (blue), histone H2A.Z (red), histone H3-triMeK27 (green). Research Interests and Goals. In particular, we focus on histone phosphorylation. Website created by: Elizabeth and Christopher Lord.

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