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cochranlab.org

Cochran Laboratory

Department of Development, Molecular and Cell Biology, Tufts University School of Medicine. 136 Harrison Ave., Boston, Massachusetts, 02111, USA. Lab and Office: Jaharis Building, Room 708. Brent Cochran, Ph.D. PHONE: (617) 636-0442 (office), (617) 636-6744(lab). MD/PhD Student (grad 2002). Graduate Student (grad 2000). Assistant Prof. of Medicine. For several years we have been working on how the c-fos promoter. We have also pioneered the use of a human near haploid cell line for somatic cell genetics.

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TUFTS UNIVERSITY

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BO●●ON , MA, 02111

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TUFTS UNIVERSITY

BRENT COCHRAN

136 HA●●●●●●N AVE.

BO●●ON , MA, 02111

US

1.61●●●●0442
co●●●●●@pobox.com

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Department of Development, Molecular and Cell Biology, Tufts University School of Medicine. 136 Harrison Ave., Boston, Massachusetts, 02111, USA. Lab and Office: Jaharis Building, Room 708. Brent Cochran, Ph.D. PHONE: (617) 636-0442 (office), (617) 636-6744(lab). MD/PhD Student (grad 2002). Graduate Student (grad 2000). Assistant Prof. of Medicine. For several years we have been working on how the c-fos promoter. We have also pioneered the use of a human near haploid cell line for somatic cell genetics.
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Cochran Laboratory | cochranlab.org Reviews

https://cochranlab.org

Department of Development, Molecular and Cell Biology, Tufts University School of Medicine. 136 Harrison Ave., Boston, Massachusetts, 02111, USA. Lab and Office: Jaharis Building, Room 708. Brent Cochran, Ph.D. PHONE: (617) 636-0442 (office), (617) 636-6744(lab). MD/PhD Student (grad 2002). Graduate Student (grad 2000). Assistant Prof. of Medicine. For several years we have been working on how the c-fos promoter. We have also pioneered the use of a human near haploid cell line for somatic cell genetics.

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cochranlab.org cochranlab.org
1

Annotated Bio resources

http://www.cochranlab.org/biolinks

Selected Biological Resources on the Web. Reviews by Tufts University Genomics and Bioinformatics. Reagents and protocols (PCR). 2007 NAR Database issue. 2006 NAR Database issue. 2005 NAR Database issue. Nucleic Acids Research, Volume 26, Issue 01. Issue of NAR devoted to molecular biology databases. Nucleic Acids Research 2003 Webserver issue -. Annual issue of NAR devoted to biological webservers. Nucleic Acids Research 2004 Database issue. Annual NAR database issue. Nucleic Acids Research Database list.

2

Top Ten Misconceptions about Immediate Early Genes (IEG's)

http://www.cochranlab.org/topten.htm

Top Ten Misconceptions about Immediate Early Genes (IEG's). 10 Everything induces c-fos. 9 IEG's are coordinately regulated. Each IEG gene appears to have a unique regulatory pattern. Serum will induce c-fos, c-jun, and junB in fibroblasts, but in the striatum cocaine induces c-fos and junB but fails to induce c-jun. TNF induces jun, but not fos. In addition, some IEG's (IL-2 for instance) have tissue specific expression patterns. 8 All IEG's are transcription factors. Some IEG's are secreted (JE and KC).

3

Microarray links.htm

http://www.cochranlab.org/BGcourse/Microarray_links.htm

The following is an excellent book on Microarray analysis:. Data Analysis Tools for DNA Microarrays. The following papers are key for selecting significant genes. Draghici S. - Statistical intelligence: effective analysis of high-density microarray data. Drug Discovery Today, in press. Draghici S., Kuklin A., Hoff B. Shams S. - Experimental Design, Analysis of Variance and Slide Quality Assessment in Gene Expression Arrays. Current Opinion in Drug Discovery and Development, vol. 4, no. 3, 2001. Free Wind...

4

Lab Meeting rotation

http://www.cochranlab.org/labmeet.htm

Wednesdays at 2 PM).

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Cochran Laboratory

Department of Development, Molecular and Cell Biology, Tufts University School of Medicine. 136 Harrison Ave., Boston, Massachusetts, 02111, USA. Lab and Office: Jaharis Building, Room 708. Brent Cochran, Ph.D. PHONE: (617) 636-0442 (office), (617) 636-6744(lab). MD/PhD Student (grad 2002). Graduate Student (grad 2000). Assistant Prof. of Medicine. For several years we have been working on how the c-fos promoter. We have also pioneered the use of a human near haploid cell line for somatic cell genetics.

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