evolutionarygenomics.com
Todd Castoe
http://www.evolutionarygenomics.com/Denizens/Castoe.html
Adaptation and evolution of protein structure and function - Molecular evolutionary dynamics and adaptation in vertebrate mitochondria - Squamate genomics and evolution - Phylogenetic methodology.
evolutionarygenomics.com
Pollock Laboratory: PClouds
http://www.evolutionarygenomics.com/ProgramsData/PClouds/PClouds.html
Package is designed to identify repeat structure in large eukaryotic genomes using oligonucleotide counts. It works efficiently on a single desktop computer with 1 Gb memory. The basic program is described in Gu et al. (2008), below, with more details, analysis of human genome, and description of element-specific P-clouds in de Koning et al. (2011). An even newer version that includes a full pipeline for running vertebrate genomes is in preparation. Is included in the zip file. Sample files include input.
evolutionarygenomics.com
Pollock Laboratory: projects
http://www.evolutionarygenomics.com/projects.html
Protein sequence, structure, and functional evolution. Adaptive coevolution and ancestral reconstruction. Evolution of mitochondrial genomes. Testing evolutionary predictions through mutagenesis and directed evolution. Further information on projects to be put up shortly.
evolutionarygenomics.com
codeml ancestral
http://www.evolutionarygenomics.com/ProgramsData/codeml_ancestral/ancestral.html
Code is available to calculate divergence and convergence. Of the codeml program from Ziheng Yang. Package. This software calculates posterior convergent and divergent substitution probabilities and their expected counts using posterior integration and amino acid substitution models: codeml-ancestral. Please see readme. File for more information. Code credits to Jason de Koning. Evidence for an ancient adaptive episode of convergent molecular evolution.
evolutionarygenomics.com
Advanced Scientific Programming
http://www.evolutionarygenomics.com/PresentationsCourses/7785/7785.html
CPBS 7785: Advanced Scientific Programming. The course is designed and directed by Prof. Pollock. In collaboration with various lab members. The course is 1 unit, and will be held in a time and place to be determined by Prof. Pollock and those who are in the class. For further enrollment information contact Elizabeth.Wethington@UCDenver.edu. The course starts soon. Scientific Programming Flyer (pdf). A Primer of Population Genetics. Hartl), if you have not already read it.
evolutionarygenomics.com
Pollock Laboratory: PLEX
http://www.evolutionarygenomics.com/ProgramsData/PLEX/PLEX.html
Phylogenetics, Likelihood, Evolution, and CompleXity. Package is designed to perform rapid likelihood analysis on large phylogenies using partial sampling of substitution histories. The basic program is described in references listed below. PLEX is under continued development. The current version 0.95 zip file. Can be downloaded here. The distribution contains code, manual files, example data files with respective control files, and mac and unix compiled versions. File, a quick start guide. A P J de Koni...
evolutionarygenomics.com
Pollock Laboratory Programs
http://www.evolutionarygenomics.com/ProgramsData/Programs.html
Ancestral TE: A program to infer relationships among replicating ancestral TE sequences in a TE family. Phylogenetics, Likelihood, Evolution, and CompleXity: A program for rapid likelihood analysis on large phylogenies using partial sampling of substitution histories. Identify repeat structure in large eukaryotic genomes using oligonucleotide counts. It works efficiently on a single desktop computer with 1 Gb memory. Three programs used to analyze coevolution of transcription factor binding sites.
evolutionarygenomics.com
Pollock Laboratory: PLEX
http://www.evolutionarygenomics.com/ProgramsData/SULDEX/SULDEX.html
Simultaneous Ultra high throughput Ligand Dissociation EXperiment. The SULDEX packages is designed to u se high throughput sequencing to simultaneously analyze binding dissociation constants for large repertoires of sequences. The basic program is described in. David D. Pollock, A. P. Jason de Koning, Hyunmin Kim, Todd A. Castoe, Mair E. A. Churchill, and Katerina J. Kechris , PloS ONE. Code is under continued development, with alpha versions available as a tarball. Current version is 0.01.
evolutionarygenomics.com
Pollock Laboratory: TFCoEvolve
http://www.evolutionarygenomics.com/ProgramsData/TFCoevolve/TFCoEvolve.html
Transcription Factor CoEvolution Analysis. The TFCoeEvolve packages is designed to analyze evolution of transcription factors. The basic set of program is described in Ken Daigoro Yokoyama and David D. Pollock,. Code and data sets are available as a compressed file. Original concept by Ken Yokoyama and DD Pollock. All programming by Ken Yokoyama. Ken Daigoro Yokoyama and David D. Pollock,.
evolutionarygenomics.com
Genomics
http://www.evolutionarygenomics.com/PresentationsCourses/7620/7620.html
HMGP, STBB, and CPBS 7620: Genomics. HMGP CPBS and STBB 7620 (Human Medical Genetics and Genomics, Structural Biology and Biochemistry, and Computational Bioscience), Spring 2014, will introduce graduate students (and interested postdocs, PRAs, and faculty) to the field of genomics. The lecture course is designed and directed by Profs. Pollock. Johnston, and Sikela, with guest lectures by Martin, Shaikh, and Spritz. Professors and students are encouraged to take a break and stretch midway). Griffiths, Ge...