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Sharp Lab, Dept of Biochemistry and Biophysics, University of Pennsylvania. How are biological structures formed and maintained? How do they manifest biological function? These are central questions in biology that date back thousands of years, to the time of Aristotle. We address the same fundamental questions at a molecular level: how is the diverse and beautiful array of protein and nucleic acid structures formed, and how do they carry out their biological function? 37th and Hamilton Walk.

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sharp lab home page | crystal.med.upenn.edu Reviews
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Sharp Lab, Dept of Biochemistry and Biophysics, University of Pennsylvania. How are biological structures formed and maintained? How do they manifest biological function? These are central questions in biology that date back thousands of years, to the time of Aristotle. We address the same fundamental questions at a molecular level: how is the diverse and beautiful array of protein and nucleic acid structures formed, and how do they carry out their biological function? 37th and Hamilton Walk.
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1 b&b dept
2 research
3 publications
4 selected
5 translation
6 software
7 people
8 teaching
9 slog
10 links
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sharp lab home page | crystal.med.upenn.edu Reviews

https://crystal.med.upenn.edu

Sharp Lab, Dept of Biochemistry and Biophysics, University of Pennsylvania. How are biological structures formed and maintained? How do they manifest biological function? These are central questions in biology that date back thousands of years, to the time of Aristotle. We address the same fundamental questions at a molecular level: how is the diverse and beautiful array of protein and nucleic acid structures formed, and how do they carry out their biological function? 37th and Hamilton Walk.

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publications_all

http://crystal.med.upenn.edu/publications_all.html

Kim A Sharp and Franz M. Matschinsky. Translation of Ludwig Boltzmann's Paper "On the Relationship between the Second Fundamental Theorem of the Mechanical Theory of Heat and Probability Calculations Regarding the Conditions for Thermal Equilibrium" (Wien. Ber. 1877, 76:373-435) Entropy (2015)17:1971-2009. Sharp, K. A. The Remarkable Hydration of the Antifreeze Protein Maxi: A Computational Study. The Journal of Chemical Physics 2014, 141. J Chem. Th. Comp. 2013, 9, 1164–1172. J Mol Biol 2006; 362:441-458.

2

people

http://crystal.med.upenn.edu/people.html

Woolverstone Hall, my old high school, and one of the finest English Public Schools. Kim Sharp, Ph.D, El Jefe. Ninad Prabhu, Ph.D Research Scientist, Glaxo Smith Kline, Westpoint PA. Qingyi (Joy) Yang, Ph.D Research Scientist, Cubist Pharmaceuticals, Boston MA. Ryan Coleman, Ph.D, Staff Scientist, Sandia National Labs. Pat Brady, Ph.D, Research Scientist, Glaxo Smith Kline, Collegeville, PA. Kelly Gallagher, Ph.D, Associate Professor of Chemistry and Biochemistry. Univ of Manitoba, Canada.

3

courses

http://crystal.med.upenn.edu/course_material.html

BMB508 Biophysics. Last taught: Fall 2014. Next: Fall 2015. BMB627 Computer Programming and Algorithms for Biophysics. GCB535 Introduction to genome science. U Penn Course Register.

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crystal.med.upenn.edu crystal.med.upenn.edu

sharp lab home page

Sharp Lab, Dept of Biochemistry and Biophysics, University of Pennsylvania. How are biological structures formed and maintained? How do they manifest biological function? These are central questions in biology that date back thousands of years, to the time of Aristotle. We address the same fundamental questions at a molecular level: how is the diverse and beautiful array of protein and nucleic acid structures formed, and how do they carry out their biological function? 37th and Hamilton Walk.

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