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dave-bridges.blogspot.com

Dave' Blog

Personal blog about life sciences and other stuff

http://dave-bridges.blogspot.com/

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Dave' Blog | dave-bridges.blogspot.com Reviews
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Personal blog about life sciences and other stuff
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1 dave' blog
2 thoughts and things
3 pages
4 research interests
5 curriculum vitae
6 validation of rnaseq
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10 posted by
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Dave' Blog | dave-bridges.blogspot.com Reviews

https://dave-bridges.blogspot.com

Personal blog about life sciences and other stuff

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dave-bridges.blogspot.com dave-bridges.blogspot.com
1

Dave' Blog: July 2012

http://dave-bridges.blogspot.com/2012_07_01_archive.html

Thursday, July 19, 2012. Why Isn't There Anonymous Post-Publication Peer Review. If pre-publication review is anonymous, and it almost always is why isnt there anonymous post-publication peer review? If there is a benefit to anonymous review, then isn't it odd that the Faculty of 1000 and most journals commenting/letter to editor mechanisms require the submitter to provide a real name and appointment. Would post-publication review of articles suck less if it were anonymous? Links to this post.

2

Dave' Blog: April 2014

http://dave-bridges.blogspot.com/2014_04_01_archive.html

Saturday, April 19, 2014. Preprints: Trying Something New in Publishing. As a trainee, having my papers reviewed by experts in the field has been both a frustrating and positive experience. It has been positive, in that in nearly every case my publications have been improved by the process. The enhancements from little embarrassing typos to new ways of conceptualizing our data, and certainly these papers are better for it. In his experience, the average has been about 9 months. What do I hope to gain?

3

Dave' Blog: November 2014

http://dave-bridges.blogspot.com/2014_11_01_archive.html

Sunday, November 9, 2014. Validation of RNAseq Experiments by qPCR? This post is in response to a couple of twitter discussions regarding whether its "useful" to do qPCR. As preliminary data for a talk can I graph transcript counts of particular genes (transcriptome data) instead of qPCR (haven't done it yet)? 8212; Sciencegurl (@sciencegurlz0) October 27, 2014. The Answer We Gave:. What Do We Mean By Validation of RNAseq Results? For the third question, I'd say you'd want to perform some non-transcripti...

4

Dave' Blog: October 2012

http://dave-bridges.blogspot.com/2012_10_01_archive.html

Tuesday, October 2, 2012. How is SREBP Regulated by Insulin? Is a transcription factor which integrates anabolic signals and drives transcription of several important lipogenic genes such as Fatty Acid Synthase, Acetyl-CoA Carboxylase and the LDL Receptor. In liver tissue ,this serves to enhance the uptake, synthesis and storage of lipid in the postprandial state. The biochemical mechanisms by which this happens is unclear but a recent paper. From the Brown and Goldstein laboratory. In the Owen et al&#46...

5

Dave' Blog: August 2012

http://dave-bridges.blogspot.com/2012_08_01_archive.html

Sunday, August 19, 2012. Rab5 Knockdown In Vivo. This paper from the Zerial Laboratory. Describes a study in which the three mammalian isoforms of Rab5 are reduced in whole livers or cultured hepatocytes by a lipid nanoparticle mediated knockdown treatment. They then analyse images from these cells and liver sections and determine that there are reduced early endosomes, late endosomes and lysosomes in cells depleted of Rab5. 7399), 465-70 PMID: 22622570. Rab5 Knockdown In Vivo. Is licensed under a Creati...

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davebridges.github.io davebridges.github.io

Curriculum Vitae

http://davebridges.github.io/cv.html

Undergraduate and Graduate Training. From the Department of Biological Sciences. In the Moorhead Laboratory. At the Department of Biological Sciences. April 2013. Research Fellow. At the Life Sciences Institute. In Dr Alan Saltiel's Laboratory. Current. Assistant Professor. At the University of Tennessee Health Science Center. University of Tennessee Health Science Center. Zolov, S. N. M W, Russell. And LS. Weisman. Proceedings of the National Academies of Science of the United States of America. Cyclic ...

davebridges.github.io davebridges.github.io

Research Interests

http://davebridges.github.io/interests.html

Phosphatidylinositol Metabolism and Functions. Phosphatidylinositol can be phosphorylated in various combinations on three positions of the inositol ring. This generates 8 possible molecules, each of which may have important roles in the regulation of intracellular events. A major focus of my research is study of the metabolism and roles of these lipids, especially. Regulation of Intracellular Trafficking. To the plasma membrane in response to insulin. To the plasma membrane. And the potential role of PI...

davebridges.github.io davebridges.github.io

News

http://davebridges.github.io/news.html

New Book Chapter on Phosphoinositides in Insulin Signaling. Several interesting review articles have recently been published in Current Topics in Microbiology regarding. Our contribution is entitled Phosphoinositides in insulin action and diabetes and is available here. There are several other excellent articles in this book, so if you are interested in this field I would encourage you to take a look. The editor, Prof. Marco Falasca. Did a fantastic job on this book and we are proud to be involved. Dave ...

davebridges.github.io davebridges.github.io

Software and Code

http://davebridges.github.io/software.html

MouseDB is a web-based application for the storage, organization and communication of data regarding experimental animals. This repository contains miscellaneous python, R and other scripts. Dave Bridges' Software and Code was created and updated by Dave Bridges. It was first published on. December 9, 2010. And was updated on. May 27, 2012. It is licensed under a Creative Commons Attribution 3.0 Unported License.

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Dave' Blog

Sunday, November 9, 2014. Validation of RNAseq Experiments by qPCR? This post is in response to a couple of twitter discussions regarding whether its "useful" to do qPCR. As preliminary data for a talk can I graph transcript counts of particular genes (transcriptome data) instead of qPCR (haven't done it yet)? 8212; Sciencegurl (@sciencegurlz0) October 27, 2014. The Answer We Gave:. What Do We Mean By Validation of RNAseq Results? For the third question, I'd say you'd want to perform some non-transcripti...

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