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The Rockefeller University » Laboratory for Cell Biology and Genetics

Saturday, March 24, 2018. LABORATORY OF CELL BIOLOGY AND GENETICS. Laboratory for Cell Biology and Genetics. A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice. Genes Dev. 28: 153-166. Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-Loop Formation. A TRF1-controlled common fragile site containing interstitial telomeric sequence. S Chromosoma 121: 465. Removal of shelterin reveals the telomere end-protection problem. Recent expansio...

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The Rockefeller University » Laboratory for Cell Biology and Genetics | delangelab.rockefeller.edu Reviews

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Saturday, March 24, 2018. LABORATORY OF CELL BIOLOGY AND GENETICS. Laboratory for Cell Biology and Genetics. A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice. Genes Dev. 28: 153-166. Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-Loop Formation. A TRF1-controlled common fragile site containing interstitial telomeric sequence. S Chromosoma 121: 465. Removal of shelterin reveals the telomere end-protection problem. Recent expansio...

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1 calendar

2 directory

3 employment

4 donate

5 research

6 publications

7 funding

8 lab members

9 titia de lange

10 current members

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calendar,directory,employment,donate,research,publications,funding,lab members,titia de lange,current members,past members,protocols,reagents,telomeres,shelterin,relevant publications,cell cycle,febs letters,science,cell,mol cell biol,ann rev genetics

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The Rockefeller University » Laboratory for Cell Biology and Genetics | delangelab.rockefeller.edu Reviews

https://delangelab.rockefeller.edu

Saturday, March 24, 2018. LABORATORY OF CELL BIOLOGY AND GENETICS. Laboratory for Cell Biology and Genetics. A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice. Genes Dev. 28: 153-166. Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-Loop Formation. A TRF1-controlled common fragile site containing interstitial telomeric sequence. S Chromosoma 121: 465. Removal of shelterin reveals the telomere end-protection problem. Recent expansio...

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delangelab.rockefeller.edu

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The Rockefeller University » Reagents

http://delangelab.rockefeller.edu/reagents

Tuesday, August 23, 2016. LABORATORY OF CELL BIOLOGY AND GENETICS. De Lange lab genetically altered mouse strains. De Lange lab Plasmids available at Addgene. De Lange lab TRF2 antibody available at Novus. How to request reagents. Our lab's TRF2 antibodies are available from Novus Biologicals. Send an email to Titia.de.Lange@rockefeller.edu. Name of the reagent. Reference to the relevant publication. Your mailing address and phone number. A FedEx account number.

2

The Rockefeller University » Current Members

http://delangelab.rockefeller.edu/currentmembers

Tuesday, August 23, 2016. LABORATORY OF CELL BIOLOGY AND GENETICS. Postdoctoral Fellows and Associates. PhD University of Rome/Sapienza. Thesis: Common fragile sites: structure, replication and their role in chromosome instability. American-Italian Cancer Foundation 2011-2012. The role of TRF1 is mediating telomere replication. PhD London Research Institute. PhD The Open University, Walton Hall, Milton Keynes, UK. 2008. Thesis: Mechanisms Responding to DNA Double Strand Breaks During S-Phase. Mechanistic...

3

The Rockefeller University » Publications

http://delangelab.rockefeller.edu/publications

Tuesday, August 23, 2016. LABORATORY OF CELL BIOLOGY AND GENETICS. H Takai, E. Jenkinson, S. Kabir, R. Babul-Hirji, N. Najm-Tehrani, D.A. Chitayat, Y.J. Crow and T. De. Lange (2016.) A POT1 mutation implicates defective telomere end fill-. Telomere truncations in Coats plus. T Kibe, M. Zimmermann and T. De Lange (2016.) TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres. Mol Cell 61: 236-246. AS Tong, J.L. Stern, A. Sfeir, M. Kartawinata, T. de Lange. Cell Reports 13: 1633- 1646. Cold Spring Ha...

4

The Rockefeller University » Protocols

http://delangelab.rockefeller.edu/protocols

Tuesday, August 23, 2016. LABORATORY OF CELL BIOLOGY AND GENETICS. Calcium Phosphate Transfection of 293T Cells. Retrovirus Production and Infection. De Lange Lab Antibodies. The Rockefeller University 1230 York Avenue, New York, NY 10065 212-327-8000.

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The Rockefeller University » Funding

http://delangelab.rockefeller.edu/funding

Tuesday, August 23, 2016. LABORATORY OF CELL BIOLOGY AND GENETICS. Current research support (PI de Lange):. NIH RO1 AG16642; Mechanism of the telomeric proliferation limit. 4/1/99-6/30/19. NCI RO1 CA160924; The role of telomere-related tetraploidization in cancer. 8/15/11 to 5/30/16. NCI RO1 CA181090; Regulation of DSB repair by 53BP1. 12/15/13 to 11/30/18. Breast Cancer Research Foundation; Genome instability and the onset of breast cancer. 10/1/03 to 09/30/16.

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The Rockefeller University » Graduate Fellows

http://digestivedisorders.rockefeller.edu/graduate

Saturday, April 22, 2017. Center for Basic and Translational Research on Disorders of the Digestive System. The Center for Basic and Translational Research on Disorders of the Digestive System is supported through the generosity of the Leona M. and Harry B. Helmsley Charitable Trust. Molecular basis of cold-activated “browning” of beige fat. Regulation of T cell plasticity and maintenance in the intestine. Role of Creatine Kinase Brain in colorectal cancer metastatic progression.

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The Rockefeller University » Laboratory for Cell Biology and Genetics

Saturday, March 24, 2018. LABORATORY OF CELL BIOLOGY AND GENETICS. Laboratory for Cell Biology and Genetics. A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice. Genes Dev. 28: 153-166. Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-Loop Formation. A TRF1-controlled common fragile site containing interstitial telomeric sequence. S Chromosoma 121: 465. Removal of shelterin reveals the telomere end-protection problem. Recent expansio...

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