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doxey.uwaterloo.ca doxey.uwaterloo.ca
1

Software

http://doxey.uwaterloo.ca/software.html

Applied Bioinformatics Research Group. Dept of Biology, UWaterloo. Lab Software and Data. Taxonomic profiling of metagenomes using custom protein families. Predicted ORFans their functions from human gut, marine, and soil metagenomes. A tool for prediction and analysis of host-pathogen mimicry. Given a protein structure (PDB file), cbsPredict will identify potential carbohydrate-binding sites based on detection of coplanar, aromatic residues located on the protein surface.

2

Home

http://doxey.uwaterloo.ca/index.html

Applied Bioinformatics Research Group. Dept of Biology, UWaterloo. The Doxey Lab is a bioinformatics. Research lab, located in the Department of Biology. We apply computational methods to predict novel molecular or systems-level functions from genomes and other "omics" datasets. Current efforts are focused largely on uncharacterized proteins from newly sequenced microbial genomes and metagenomes. There are opportunities for graduate students and potential BIOL 499. Recent papers highlighting our work.

3

Teaching

http://doxey.uwaterloo.ca/teaching.html

Applied Bioinformatics Research Group. Dept of Biology, UWaterloo. BIOL 469: Genomics, Fall Term. BIOL 266: Introduction to Computational Biology, Fall Term. There is now a. For Undergraduate Honours Science Students. This will be part of the 2016/2017 calendar. See here. Related courses at the University of Waterloo. From the Undergraduate Course Calendar. BIOL 349 - Synthetic Biology Project Design. BIOL 359 - Evolution. BIOL 364 - Mathematical Modelling in Biology. BIOL 365 - Methods in Bioinformatics.

4

Resources

http://doxey.uwaterloo.ca/resources.html

Applied Bioinformatics Research Group. Dept of Biology, UWaterloo. Doxey Lab Google Group. Homolog detection and sequence alignment. R package), Figtree. Genome Browsing and Analysis. Genome Browser, Galaxy. Haplotype Analysis and Visualization.

5

Publications

http://doxey.uwaterloo.ca/publications.html

Applied Bioinformatics Research Group. Dept of Biology, UWaterloo. Cheng J, Romantsov R, Engel J, Doxey AC, Rose DR, Neufeld JD, Charles T. (2017) Functional metagenomics reveals novel beta-galactosidases not predictable from gene sequences. Adams J, Mansfield MJ, Richard DJ, Doxey AC. (2017) Lineage-specific mutational clustering in protein structures predicts evolutionary shifts in function. Advance online publication: [pubmed]. Advance online publication: [pubmed]. Advance online publication: [doi].

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Bejerano Lab, Stanford University

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PhD, Hebrew University. Microsoft Research Faculty Fellow. Alfred P. Sloan Fellow. PhD, University of North Carolina, Chapel Hill. Joint with Sue McConnell. PhD, Weizmann Institute of Science. Affiliation: Developmental Biology Dept. MS, Vienna University of Technology. Affiliation: Computer Science Dept. BS, Stanford University. Affiliation: Developmental Biology Dept. Joint with Kristy Red-Horse. BS, UC Berkeley. Affiliation: Computer Science Dept. MPhil, Cambridge University. BS, University of Chicago.

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Applied Bioinformatics Research Group. Dept of Biology, UWaterloo. The Doxey Lab is a bioinformatics. Research lab, located in the Department of Biology. Our focus is on genome analysis, molecular evolution, and protein structural bioinformatics. A long-term goal is to combine these above areas in computational methods to predict and design biological function. We collaborate closely with a number of labs from Waterloo and beyond. There are opportunities for graduate students and potential BIOL 499.

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