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Distribution in blood, cellular distribution drug penetration to CNS. Drug excretion. salivary excretion. Drug metabolism, plasma-protein binding and its effect on drug disposition. Illustrate the different routes of drug degradation. Suggest the means for protection of drugs. (99) 12 4. Write short notes on (a) Renal excretion, (b) Plasma protein binding. (98) 8 8. Why is distribution of a drug not uniform throughout the body? Discuss the factors affecting drug distribution. (97) 16. Distribution of a d...

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