edarstudy.eu edarstudy.eu

edarstudy.eu

EDARstudy

Biomarkers for Alzheimer’s disease. Welcome to the website of the EDAR study. The EDAR study is a European collaborative study, which aims to develop and validate new biomarkers for Alzheimer’s disease. In order to validate the assay for beta amyloid oligomers, cerebrospinal fluid and plasma will be repeatedly collected in subjects with Alzheimer’s disease, other types of dementia, Mild Cognitive Impairment, and control subjects. EDAR is the acronym for Beta amyloid oligomers in the e.

http://www.edarstudy.eu/

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EDARstudy | edarstudy.eu Reviews
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Biomarkers for Alzheimer’s disease. Welcome to the website of the EDAR study. The EDAR study is a European collaborative study, which aims to develop and validate new biomarkers for Alzheimer’s disease. In order to validate the assay for beta amyloid oligomers, cerebrospinal fluid and plasma will be repeatedly collected in subjects with Alzheimer’s disease, other types of dementia, Mild Cognitive Impairment, and control subjects. EDAR is the acronym for Beta amyloid oligomers in the e.
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2 edar home
3 summary for non technicians
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5 partners
6 preliminary results
7 publications
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9 contact information
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EDARstudy | edarstudy.eu Reviews

https://edarstudy.eu

Biomarkers for Alzheimer’s disease. Welcome to the website of the EDAR study. The EDAR study is a European collaborative study, which aims to develop and validate new biomarkers for Alzheimer’s disease. In order to validate the assay for beta amyloid oligomers, cerebrospinal fluid and plasma will be repeatedly collected in subjects with Alzheimer’s disease, other types of dementia, Mild Cognitive Impairment, and control subjects. EDAR is the acronym for Beta amyloid oligomers in the e.

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1

EDARstudy

http://www.edarstudy.eu/outline.html

Biomarkers for Alzheimer’s disease. Beta amyloid oligomers in the early diagnosis of AD and as marker for treatment response. EC contribution in euro:. Due to their low concentration, oligomers cannot be measured with regular techniques. In the present study, ultra-sensitive assays will be used in order to measure oligomers in vivo. Thus, the project will bring recent scientific discoveries in the early pathophysiology of AD to clinical application using innovative technological methods. Aim of this work...

2

EDARstudy

http://www.edarstudy.eu/summary_nt.html

Biomarkers for Alzheimer’s disease. Alzheimer’s disease is one of the most common causes of dementia. It currently affects 4 million subjects in the European Union. The prevalence of Alzheimer’s disease is expected to increase substantially the next decades due to the aging population. Alzheimer’s disease severely affects the quality of life of patients and their relatives. It also poses a major burden to the health care system. Aims of the study.

3

EDARstudy

http://www.edarstudy.eu/results.html

Biomarkers for Alzheimer’s disease. 1 Oligomer antibody development. 3 Clinical data collection. We have included 56 controls, 117 subjects with MCI, 108 subjects with AD, and 58 subjects with other dementias. We have established a database with clinical data and we set-up a biobank, which included 5300 CSF samples, 3000 plasma samples, 1900 serum samples, and DNA for 314 subjects. The follow-up of these subjects is ongoing.

4

EDARstudy

http://www.edarstudy.eu/publications.html

Biomarkers for Alzheimer’s disease. Toxicity in cell models is mediated by selective uptake. SM Chafekar, F. Baas and W. Scheper (2008a). Biochimica et biophysica acta 2008;1782(9):523-31;. Http:/ dx.doi.org/10.1016/j.bbadis.2008.06.003. 1-42 production sensitizes neuroblastoma cells for ER stress toxicity. SM Chafekar, R. Zwart, R. Veerhuis, H. Vanderstichele, F. Baas and W. Scheper. Current Alzheimer research 2008;5:469-74;. Http:/ www.ncbi.nlm.nih.gov/pubmed/18855588? Neurology 2009;73;744-745;. Ron W...

5

EDARstudy

http://www.edarstudy.eu/partners.html

Biomarkers for Alzheimer’s disease. The following partners are involved in the EDAR study:. VU University Medical Centre. Dr Pieter Jelle Visser. Profdr. Wim Buurman. University of Amsterdam/ Academic Medical Centre. Profdr. Lars-Olof Wahlund. Aristotle University of Thessaloniki. Profdr. Magda Tsolaki. Profdr. Rik Vandenberghe. Profdr. Gunhild Waldemar. Ludwig Maximilian University of Munich. Profdr. Harald Hampel. Profdr. Frans Verhey. Abbott GmbH and Co KG. Central Institute for Mental Health.

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Biomarkers for Alzheimer’s disease. Welcome to the website of the EDAR study. The EDAR study is a European collaborative study, which aims to develop and validate new biomarkers for Alzheimer’s disease. In order to validate the assay for beta amyloid oligomers, cerebrospinal fluid and plasma will be repeatedly collected in subjects with Alzheimer’s disease, other types of dementia, Mild Cognitive Impairment, and control subjects. EDAR is the acronym for Beta amyloid oligomers in the e.

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