frankjacobslab.com

University of Amsterdam - The Jacobs Lab

Evolutionary impact of Retrotransposons. People in the Jacobs Lab. The impact of primate genome evolution on human gene-regulatory networks. This is the main research interest in my group. In particular, how has the evolution of the human genome shaped gene regulatory networks involved in human brain development. In previous work (. Jacobs et al., 2014. As a result of this evolutionary armsrace. Our lab currently investigates how this extra layer of retrotransposon-mediated gene control has re-shaped gen...

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University of Amsterdam - The Jacobs Lab | frankjacobslab.com Reviews

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Evolutionary impact of Retrotransposons. People in the Jacobs Lab. The impact of primate genome evolution on human gene-regulatory networks. This is the main research interest in my group. In particular, how has the evolution of the human genome shaped gene regulatory networks involved in human brain development. In previous work (. Jacobs et al., 2014. As a result of this evolutionary armsrace. Our lab currently investigates how this extra layer of retrotransposon-mediated gene control has re-shaped gen...

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University of Amsterdam - The Jacobs Lab | frankjacobslab.com Reviews

https://frankjacobslab.com

Evolutionary impact of Retrotransposons. People in the Jacobs Lab. The impact of primate genome evolution on human gene-regulatory networks. This is the main research interest in my group. In particular, how has the evolution of the human genome shaped gene regulatory networks involved in human brain development. In previous work (. Jacobs et al., 2014. As a result of this evolutionary armsrace. Our lab currently investigates how this extra layer of retrotransposon-mediated gene control has re-shaped gen...

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frankjacobslab.com

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University of Amsterdam - Job positions

http://www.frankjacobslab.com/Job-positions

Evolutionary impact of Retrotransposons. People in the Jacobs Lab. The Jacobs Lab is looking for 1 PhD student. With a special interest in investigating how recent and ongoing retrotransposon invasions in our genome have contributed to the evolution of human neuronal gene expression networks. Starting date between Feb-June 2018: For more details, please send an email to f.m.j.jacobs@uva.nl.

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University of Amsterdam - People in the Jacobs Lab

http://www.frankjacobslab.com/People-in-the-Jacobs-Lab

Evolutionary impact of Retrotransposons. People in the Jacobs Lab. People in The Jacobs Lab. Anouk van den Bout. Dec 2014- Oct 2015. University of Barcelona, Spain. Feb 2016- June 2016. University of Barcelona, Spain.

3

University of Amsterdam - Publications

http://www.frankjacobslab.com/Publications

Evolutionary impact of Retrotransposons. People in the Jacobs Lab. FMJ Jacobs*, D. Greenberg*, N. Nguyen, M. Haeussler, A. Ewing, S. Katzman, B. Paten, S.R. Salama, D. Haussler. An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons. 516, 242 245 (11 December 2014). Jul; 136(14): 2363-2373. FMJ Jacobs, S. van Erp, A.J.A. van der Linden, L. von Oerthel, J.P.H. Burbach, M.P. Smidt (2009). Pitx3 potentiates Nurr1 in dopamine ...Feb; 136(4): 531-540. FMJ Jacobs*, S....

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University of Amsterdam - Evolutionary impact of Retrotransposons

http://www.frankjacobslab.com/Evolutionary-impact-of-Retrotransposons

Evolutionary impact of Retrotransposons. People in the Jacobs Lab. The impact of retrotransposon invasions on the evolution of human gene regulatory networks. In previous work (. Jacobs et al., 2014. We have found that two primate-specific KRAB zinc finger gene have recently evolved to repress the activity of SVA and L1PA retrotransposons. This study shows how our genome is in a continuous battle against retrotransposon invasions; an evolutionary arms race. Intriguingly, the genome’s effort to silence re...

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University of Amsterdam - Lab photos

http://www.frankjacobslab.com/Lab-photos

Evolutionary impact of Retrotransposons. People in the Jacobs Lab. The whole Jacobs Lab gang in 2017: From left to right: Frank Jacobs (PI), Elise van Bree (PhD student), Paula Schmidt, (MSc student), Lotte Russo, (MSc student), Gerrald Lodewijk (PhD student), Hedwig Dolstra (MSc student), Whitney Jordaan (MSc student), Elias Brandorff (PhD student), Anne-Fleur Schneider (BSc student), Nina Haring (PhD student), Stijn Robben (BSc student), Judith Roels (MSc student), Josse Poppinga (BSc student).

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hpscreg.eu

Projects · hPSCreg

https://hpscreg.eu/browse/projects

EU-funded projects using hPSC. 1st Sep 2017 - 31st Aug 2022. Probing the Reversibility of Autism Spectrum Disorders by Employing in vivo and in vitro Models. Http:/ gnovarino.wixsite.com/novarino-lab. 1st Mar 2017 - 28th Feb 2022. Microglia action towards neuronal circuit formation and function in health and disease. Http:/ ist.ac.at/research/life-sciences/siegert-group/. 1st Jan 2017 - 1st Jan 2022. Decoding the Epigenomic Regulatory Code by the Use of Single Cell Technologies. Http:/ www.pdn.ca...1st J...

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University of Amsterdam - The Jacobs Lab

Evolutionary impact of Retrotransposons. People in the Jacobs Lab. The impact of primate genome evolution on human gene-regulatory networks. This is the main research interest in my group. In particular, how has the evolution of the human genome shaped gene regulatory networks involved in human brain development. In previous work (. Jacobs et al., 2014. As a result of this evolutionary armsrace. Our lab currently investigates how this extra layer of retrotransposon-mediated gene control has re-shaped gen...

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