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Acute Lymphocytic Leukemia & PAX5 - ALL Home

This web page was produced as an assignment for  Genetics 564 , an undergraduate capstone course at UW-Madison.

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Acute Lymphocytic Leukemia & PAX5 - ALL Home | gallenbergergen564s16.weebly.com Reviews
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This web page was produced as an assignment for  Genetics 564 , an undergraduate capstone course at UW-Madison.
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2 what is cancer
3 specific aims
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5 homology
6 phylogeny
7 interaction networks
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Acute Lymphocytic Leukemia & PAX5 - ALL Home | gallenbergergen564s16.weebly.com Reviews

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This web page was produced as an assignment for  Genetics 564 , an undergraduate capstone course at UW-Madison.

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Domains - Acute Lymphocytic Leukemia & PAX5

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Acute Lymphocytic Leukemia and PAX5. This web page was produced as an assignment for. An undergraduate capstone course at UW-Madison. What are Protein Domains? Protein Domains are conserved sequences of amino acids that contribute to the structure or function of a transcribed protein [ 1. Many evolutionary studies have used protein domains to track the evolution of protein function [ 3. Which Protein Domains are present in PAX5 in humans? The PAX domain has been shown to interact. Another protein family ...

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Conclusions - Acute Lymphocytic Leukemia & PAX5

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Acute Lymphocytic Leukemia and PAX5. This web page was produced as an assignment for. An undergraduate capstone course at UW-Madison. Acute Lymphocytic Leukemia (ALL), which is also known as Acute Lymphoblastic Leukemia, is a type of cancer that will kill an estimated 1430 people this year, according to the American Cancer Society's predictions [ 1. About two thirds of cases are children under five, while one third are older [ 1. By using NCBI's BLAST. Then, I zoomed in on their sequences, and found many...

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Phenotypes - Acute Lymphocytic Leukemia & PAX5

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Acute Lymphocytic Leukemia and PAX5. 8203;This web page was produced as an assignment for. An undergraduate capstone course at UW-Madison. What are mutant phenotypes? What mutant phenotypes are exhibited by organisms with PAX5? In Zebrafish, knockdown of PAX5 disrupts development of the vestibular macula, a structure within the ear that transmits signals to the vestibulocochlear nerve [ 1. Hearing is not affected. Horowitz MC, Xi Y, Pflugh DL, Hesslein DG, Schatz DG, Lorenzo JA, Bothwell AL. Pax-5 de...

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Predicted Phosphorylation - Acute Lymphocytic Leukemia & PAX5

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Acute Lymphocytic Leukemia and PAX5. This web page was produced as an assignment for. An undergraduate capstone course at UW-Madison. Which predicts potential Serine, Threonine, and Tyrosine phosphorylation sites [ 1. Where is PAX5 predicted to be phosphorylated? There are many predicted phosphorylation sites for PAX5. Notably, many of them appear to be within the PAX2C domain. Further, there is one high peak of Threonine phosphorylation within the PAX. Http:/ www.cbs.dtu.dk/services/NetPhos/.

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Interaction Networks - Acute Lymphocytic Leukemia & PAX5

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Acute Lymphocytic Leukemia and PAX5. 8203;This web page was produced as an assignment for. An undergraduate capstone course at UW-Madison. What are protein interaction networks? Protein Interaction Networks are a visual way to represent the relationship between proteins as they function within an organism. They are developed using programs like STRING. What does the PAX5 protein interact with? Human PAX5 Interaction Network. Mouse PAX5 Interaction Network. Zebrafish PAX5 Interaction Network.

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Projects - Genetics 564

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Spring 2016 Student Projects. Matthew Busalacchi: Familial Melanoma and Pigmentation (MC1R). Salvador Carranza: Cystinosis (CTNS). Mikayla Gallenberger: Acute Lymphoblastic Leukemia (PAX5). Sara Grange: Synesthesia (KIAA0319). Aidan Holmes: Wilson Disease (ATP7B). Bailey Marquardt: Developmental Dyslexia (ROBO1). Troy Meikle: Autoimmune lymphoproliferative syndrome (FAS). Mary Mohr: Cardiovascular Disease in Women (BCAR1/p130CAS). Kathryn Ness: CHARGE Syndrome (CHD7). Tia Ramirez: FOXG1 Syndrome (FOXG1).

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Acute Lymphocytic Leukemia & PAX5 - ALL Home

Acute Lymphocytic Leukemia and PAX5. This web page was produced as an assignment for. An undergraduate capstone course at UW-Madison. What is Acute Lymphocytic Leukemia? When mutations arise in the PAX5 gene, such as those in the amino acid Glycine-183, B cells develop immaturely and accumulate in the bone marrow. This is a key component of the genetic phenotype of ALL. In the United States in 2015, there were an estimated 6,250 new cases of ALL, with slightly more in males [. In 25% of adult patients [ 6.

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