tllab.org
Blog | Lappalainen Lab | Functional Genomics @ NYGC
https://tllab.org/blog
Functional Genomics @ NYGC. The sound of a gene breaking. May 18, 2015. Equal contribution; corresponding authors. If you listened to your cells very carefully, would you be able to hear when a gene breaks? In a new paper in Science, we show that this is, in a way, possible: by analysis of huge RNA-sequencing data sets, we can detect cellular effects of protein-truncating variants in the genome. Trending: rare variants in human disease. In 2013, and the new GTEx project. Getting rid of the nonsense.
geuvadis.org
RNA sequencing project
http://www.geuvadis.org/web/geuvadis/RNAseq-project
Ethical Social Legal Issues. Geuvadis RNA sequencing project of 1000 Genomes samples. The main paper presenting the data set and summarizing the key findings, with a focus on transcriptome variantion and its genetic component has been published in Nature in September 2013 by Lappalainen et al.: Transcriptome and genome sequencing uncovers functional variation in humans. http:/ dx.doi.org/10.1038/nature12531. Where quantifications and QTLs can be viewed, searched, and downloaded. Data access schema for Ge...
geuvadis.org
RNA sequencing project
http://www.geuvadis.org/web/geuvadis/rnaseq-project;jsessionid=16BC828F8CE6FB96849988664A25B894
Ethical Social Legal Issues. Geuvadis RNA sequencing project of 1000 Genomes samples. The main paper presenting the data set and summarizing the key findings, with a focus on transcriptome variantion and its genetic component has been published in Nature in September 2013 by Lappalainen et al.: Transcriptome and genome sequencing uncovers functional variation in humans. http:/ dx.doi.org/10.1038/nature12531. Where quantifications and QTLs can be viewed, searched, and downloaded. Data access schema for Ge...