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Global Blood Therapeutics

Enabling Extraordinary Lives for Sickle Cell Disease Patients. Learn more ». Transforming Treatment of Severe Blood Disorders. Learn more ». A Commitment to Serving Patients and Their Families. Learn more ». Through its scientific foundation, Global Blood Therapeutics (GBT) is committed to transforming the treatment of severe blood disorders. GBT440 targets the underlying mechanism of red blood cell sickling, which provides the potential to treat SCD rather than only its associated symptoms. Apr 14, 2015.

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Global Blood Therapeutics | globalbloodtx.com Reviews
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Enabling Extraordinary Lives for Sickle Cell Disease Patients. Learn more ». Transforming Treatment of Severe Blood Disorders. Learn more ». A Commitment to Serving Patients and Their Families. Learn more ». Through its scientific foundation, Global Blood Therapeutics (GBT) is committed to transforming the treatment of severe blood disorders. GBT440 targets the underlying mechanism of red blood cell sickling, which provides the potential to treat SCD rather than only its associated symptoms. Apr 14, 2015.
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Global Blood Therapeutics | globalbloodtx.com Reviews

https://globalbloodtx.com

Enabling Extraordinary Lives for Sickle Cell Disease Patients. Learn more ». Transforming Treatment of Severe Blood Disorders. Learn more ». A Commitment to Serving Patients and Their Families. Learn more ». Through its scientific foundation, Global Blood Therapeutics (GBT) is committed to transforming the treatment of severe blood disorders. GBT440 targets the underlying mechanism of red blood cell sickling, which provides the potential to treat SCD rather than only its associated symptoms. Apr 14, 2015.

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Investor Overview | Investors | Global Blood Therapeutics

Global Blood Therapeutics Inc at 35th Annual J.P. Morgan Healthcare Conference. 160;at 3:00 pm PT. Global Blood Therapeutics Inc at 35th Annual J.P. Morgan Healthcare Conference. Tuesday, January 10, 2017 . 3:00 pm PT  . Click here for webcast. Click here to add this event to your calendar. 35th Annual J.P. Morgan Healthcare Conference Presentation. GBT at the 2016 American Society of Hematology (ASH) Annual Meeting. 160;at 12:15 pm PT. GBT at the 2016 American Society of Hematology (ASH) Annual Meeting.

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1

Our Approach | Global Blood Therapeutics

http://www.globalbloodtx.com/content/science/platform.php

Our Approach to SCD. About Hypoxemic Pulmonary Disorders. GBT is committed to transforming the treatment of severe blood-based disorders. Our scientific focus and mission is to develop novel medicines that treat grievous blood-based disorders by arresting the underlying chemical and biological mechanisms of the disease. Our efforts have produced a pipeline of novel, mechanism-based small molecule therapeutics that we believe have the potential to address the underlying chemical and biological mechanisms ...

2

Values | Global Blood Therapeutics

http://www.globalbloodtx.com/content/about/values.php

Our Approach to SCD. About Hypoxemic Pulmonary Disorders. To revolutionize the treatment of grievous blood-based conditions. Science dedicated to patients. Embrace open communication and debate. Trust, respect, and accountability. One team, one purpose. Always do the right thing. Global Blood Therapeutics Inc. Home.

3

Publications and Abstracts | Global Blood Therapeutics

http://www.globalbloodtx.com/content/science/publications.php

Our Approach to SCD. About Hypoxemic Pulmonary Disorders. British Journal of Haematology. GBT440 Increases Haemoglobin Oxygen Affinity, Reduces Sickling and Prolongs RBC Half-life in a Murine Model of Sickle Cell Disease. DOI: 10.1111/bjh.14214:. Http:/ onlinelibrary.wiley.com/doi/10.1111/bjh.14214/abstract. GBT440, A Novel Sickle Haemoglobin Polymerisation Inhibitor, Increases Haemoglobin Oxygen Affinity And Results In A Rapid Improvement In Haemolysis And Anaemia. GBT440 Demonstrates High Specificity f...

4

Hypoxemic Pulmonary Disorders | Global Blood Therapeutics

http://www.globalbloodtx.com/content/pipeline/hypoxemic-pulmonary-disorders.php

Our Approach to SCD. About Hypoxemic Pulmonary Disorders. Our preclinical and preliminary clinical investigation of GBT440 demonstrated the compound’s ability to increase the oxygen affinity of hemoglobin. This mechanism has important therapeutic potential beyond SCD and, as such, we are also planning to develop GBT440 as a potential treatment for acute and chronic hypoxemic pulmonary disorders. Global Blood Therapeutics Inc. Home.

5

Patient Community | Global Blood Therapeutics

http://www.globalbloodtx.com/content/patients/index.php

Our Approach to SCD. About Hypoxemic Pulmonary Disorders. Our team at GBT shares a passion for great science and an authentic commitment to making a difference in the lives of patients with grievous, blood-based conditions. Through our ongoing drug discovery and development work, we are creating treatments that address the root causes of various blood-based disorders, thus providing patients a way to manage their health, extend their life expectancy and improve their quality of life.

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Companies | The Jacobson Laboratory at UCSF

https://jacobsonlab.wordpress.com/about/companies

The Jacobson Laboratory at UCSF. Computational structural biology, biophysics, and drug design. Skip to primary content. Matt is a co-founder of. He also serves on the Scientific Advisory Board of Schrodinger LLC, which has commercialized software originally written by him as part of Prime:. The Jacobson lab has also benefited from a long-term collaboration with Pfizer. Blog at WordPress.com.

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Retronyma | Another direction for global health | Page 2

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Another direction for global health. Newer posts →. The Business of Global Health No. 20. January 29, 2015. The collaboration is with the Institut Pasteur and the South African Tuberculosis Vaccine Initiative and will test Myriad’s TruCulture system in differentiating patients with active and latent tuberculosis. The program is funded through a grant to the Pasteur from the Gates Foundation that has supported other TB diagnostics product development, e.g., by Alere and Cepheid (see my p...Last June Gilea...

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Sickle Cell 101

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Winners of the Sickle Cell Advocate of the Year Awards. Sickle Cell Plus Bulletin. Ask Dr. Q. Feat Michael DeBaun, MD. Congratulations to our winners! Allan F. Platt, PA-C, MMSc. 2015 Sickle Cell Advocate of the Year. 2015 International Sickle Cell Advocate of the Year. Award plaque honoring their achievement. Feature on Sickle Cell 101's social media, website and newsletter. Please take the time to congratulate. Allan F. Platt. Please also congratulate our runner-up candidates. Back to SCAY Award.

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About the Speakers

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Skip to Main Content. September 8, 2016 Four Seasons Hotel, New York, NY. This page contains links to third-party internet sites.*. Annual Sickle Cell Disease Therapeutics Conference was held on September 3, 2015. Please check back for 2016 conference information. Jonca Bull, M.D. - US Food and Drug Administration. Assistant Commissioner for Minority Health. US Food and Drug Administration. Sonja L. Banks - Sickle Cell Disease Association of America, Inc. Medical University of South Carolina. Robert Morl...

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News – Axis Advocacy

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All the news that are relevant for our small community. Sickle Cell Disease Coalition Website Up and Running. March 1, 2017. In Advice from Nancy. Http:/ www.axisadvocacy.org/wp-content/uploads/2016/02/axislogo-2.png. Http:/ www.axisadvocacy.org/wp-content/uploads/2016/02/axislogo-2.png. Sickle Cell Disease Coalition Website Up and Running. Get Email Updates from the Sickle Cell Disease Coalition. February 28, 2017. Http:/ www.axisadvocacy.org/wp-content/uploads/2016/02/axislogo-2.png. February 28, 2017.

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Sickle Cell 101

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Sickle Cell 101 relies on generous contributions from our supporters to continue our work. We would like to take this opportunity to thank our sponsors. If you are interested in sponsoring or learning more about our sponsorship packages,. Sponsor Sickle Cell 101 today. Magnussen Lexus of Fremont. The Cloverleaf Family Bowl. Sickle Cell Plus Bulletin. Ask Dr. Q. Feat Michael DeBaun, MD. Report a problem with this website. Ask Dr. Q.

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Discover. Launch. Build. Our Mission and Core Values. Sign up for weekly portfolio company news alerts here. Third Rock Company Profile. Third Rock Team Profile. Third Rock Spring 2016 Newsletter. Third Rock News and Events. September 24, 2016. Third Rock Ventures’ Venture Partner Phil Reilly to receive the Henri Termeer Lifetime Achievement Award at the 5th Annual Tribute to Champions of Hope. Raquo; Read More. May 23, 2016. Raquo; Read More. April 25, 2016. Raquo; Read More. April 6, 2016. Global Blood...

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Global Blood Therapeutics

Enabling Extraordinary Lives for Sickle Cell Disease Patients. Learn more ». Transforming Treatment of Severe Blood Disorders. Learn more ». A Commitment to Serving Patients and Their Families. Learn more ». Through its scientific foundation, Global Blood Therapeutics (GBT) is committed to transforming the treatment of severe blood disorders. GBT440 targets the underlying mechanism of red blood cell sickling, which provides the potential to treat SCD rather than only its associated symptoms. Apr 14, 2015.

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