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Paul De Koninck Lab | greenspine.caPaul De Koninck lab investigates the cellular and molecular mechanisms used by neurons to decode synaptic and electrical activities that propagate through neural circuits.
http://www.greenspine.ca/
Paul De Koninck lab investigates the cellular and molecular mechanisms used by neurons to decode synaptic and electrical activities that propagate through neural circuits.
http://www.greenspine.ca/
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Paul De Koninck Lab | greenspine.ca | greenspine.ca Reviews
https://greenspine.ca
Paul De Koninck lab investigates the cellular and molecular mechanisms used by neurons to decode synaptic and electrical activities that propagate through neural circuits.
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Publications - Paul De Koninck Lab
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Paul De Koninck Lab. Pi HJ, Otmakhov N, El Gaamouch F, Lemelin D, De Koninck P, Lisman J. CaMKII control of spine size and synaptic strength: role of phosphorylation states and nonenzymatic action. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14437-42. Opazo P, Labrecque S, Tigaret CM, Frouin A, Wiseman PW, De Koninck P, Choquet D. CaMKII triggers the diffusional trapping of surface AMPARs through phosphorylation of stargazin. Neuron. 2010 Jul 29;67(2):239-52. J Neurosci. 2010 Jun 30;30(26):8704-9.
Images - Paul De Koninck Lab
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Paul De Koninck Lab. Click here for a larger slideshow. MGFP neuron2.jpg,. Neuron culture 800px.jpg, GFP neuron.html, media/quantum dots c.jpg, neurons and glial cells.jpg, rainbowtadpole1 c.jpg,. MGFP neuron2 200px.jpg.
Paul De Koninck Lab
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Paul De Koninck Lab. Our lab investigates the cellular and molecular mechanisms used by neurons to decode synaptic and electrical. We combine several techniques to study these questions:. Neuronal tissue culture (dissociated cultures or brain slices). Electrophysiological recordings (patch-clamping) to study the functional impact of the molecular reorganization at synapses. Biochemistry for structure/function studies in vitro and to measure protein expression and modification. CRIUSMQ). We collaborat...
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Funding - Paul De Koninck Lab
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Paul De Koninck Lab. Our research endeavors are made possible by the following agencies:.
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Aller à la navigation. Aller au contenu principal. Offres d'emploi et stages. Éthique de la recherche. Ressource intégrée de recherche sur le génome humain (en anglais). The Genome Database (en anglais). Arborescence psychiatrie et psychologie : sites francophones. Société canadienne de schizophrénie. Consortium d'imagerie en neurosciences et santé mentale de Québec (CINQ). Pages personnelles des chercheurs. Site du Dr Keating. Laboratoire du Dr Daniel Côté. Laboratoire du Dr Paul De Koninck.
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Aller à la navigation. Aller au contenu principal. Offres d'emploi et stages. Éthique de la recherche. Plateforme de tri cellulaire. Plateforme de microscopie électronique. Procedure to fill the 120 l liquid nitrogen Dewar. Ressource intégrée de recherche sur le génome humain (en anglais). The Genome Database (en anglais). Arborescence psychiatrie et psychologie : sites francophones. Société canadienne de schizophrénie. Consortium d'imagerie en neurosciences et santé mentale de Québec (CINQ).
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Paul De Koninck Lab | greenspine.ca
Skip to main content. Paul De Koninck Lab. We focus primarily on the signaling pathway at excitatory synapses, which are formed on dendritic spines. In this pathway, we monitor the spatial dynamics and interactions of glutamate receptors (NMDA and AMPA), signaling enzymes (CaMKII, calpain) and structural proteins (PSD95, actin, tubulin) that support synaptic plasticity. We combine functional imaging (Ca. Our lab is in the division of Cellular and Molecular Neuroscience at the CERVO Brain Research Centre.
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