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The Importance of Chemistry in High-throughput Screening | This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS

The Importance of Chemistry in High-throughput Screening. This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS. Hoes show their ***** in public. PAINS in the Literature? PAINS, Not PAINS, or Promiscuous? September 6, 2014. Here we go again. Yes, 1-3. Lose activity when Triton is added to the assay. But why would 4. Have such similar activities under either conditions? Newest PAIN structure revealed. September 3, 2014. The newest PAINs structure on the block....

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The Importance of Chemistry in High-throughput Screening | This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS | htspains.com Reviews

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The Importance of Chemistry in High-throughput Screening. This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS. Hoes show their ***** in public. PAINS in the Literature? PAINS, Not PAINS, or Promiscuous? September 6, 2014. Here we go again. Yes, 1-3. Lose activity when Triton is added to the assay. But why would 4. Have such similar activities under either conditions? Newest PAIN structure revealed. September 3, 2014. The newest PAINs structure on the block....

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1 the usual suspects

2 useful links

3 rhodanines redux

4 posted on

5 painsmaster

6 see also

7 posted in uncategorized

8 ahead of print

9 badapple

10 the editor

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The Importance of Chemistry in High-throughput Screening | This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS | htspains.com Reviews

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The Importance of Chemistry in High-throughput Screening. This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS. Hoes show their ***** in public. PAINS in the Literature? PAINS, Not PAINS, or Promiscuous? September 6, 2014. Here we go again. Yes, 1-3. Lose activity when Triton is added to the assay. But why would 4. Have such similar activities under either conditions? Newest PAIN structure revealed. September 3, 2014. The newest PAINs structure on the block....

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Useful Links | The Importance of Chemistry in High-throughput Screening

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The Importance of Chemistry in High-throughput Screening. This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS. PAINS in the Literature? PAINS, Not PAINS, or Promiscuous? July 13, 2013. No Comments ↓. Fragment-based Drug Design Blog: Practical Fragments. Fragment-Based Drug Discovery: LinkedIn Group. Scripps, Florida: Promiscuity Filtering. Mobyle@RPBS: PAINS Filtering and Other Tools. Cambridge MedChem Consulting: Drug Discovery Resources. You may use these.

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Rhodanines Redux | The Importance of Chemistry in High-throughput Screening

http://www.htspains.com/rhodanines-redux

The Importance of Chemistry in High-throughput Screening. This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS. PAINS in the Literature? PAINS, Not PAINS, or Promiscuous? September 6, 2014. Here we go again. Yes, 1-3. Lose activity when Triton is added to the assay. But why would 4. Have such similar activities under either conditions? 8249; Newest PAIN structure revealed. 2016 The Importance of Chemistry in High-throughput Screening.

3

New Promiscuity Engine Released (MLS) | The Importance of Chemistry in High-throughput Screening

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The Importance of Chemistry in High-throughput Screening. This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS. PAINS in the Literature? PAINS, Not PAINS, or Promiscuous? New Promiscuity Engine Released (MLS). New Promiscuity Engine Released (MLS). April 24, 2014. BioActivity Data Associative Promiscuity Pattern Learning Engine) learns from frequent hitters found in the Molecular Libraries Screening program, and flags promiscuous compounds.

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HTSpains now on Facebook | The Importance of Chemistry in High-throughput Screening

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The Importance of Chemistry in High-throughput Screening. This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS. PAINS in the Literature? PAINS, Not PAINS, or Promiscuous? HTSpains now on Facebook. HTSpains now on Facebook. March 19, 2014. 8249; What to make of bis-chalcones? New Promiscuity Engine Released (MLS). 2016 The Importance of Chemistry in High-throughput Screening.

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painsmaster | The Importance of Chemistry in High-throughput Screening

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The Importance of Chemistry in High-throughput Screening. This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS. PAINS in the Literature? PAINS, Not PAINS, or Promiscuous? View all posts by painsmaster. September 6, 2014. Here we go again. Yes, 1-3 lose activity when Triton is added to the assay. But why would 4 and 5 have such similar activities under either conditions? Read more ›. Newest PAIN structure revealed. September 3, 2014. Where have I seen this before?

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practicalfragments.blogspot.com

Practical Fragments: Who's Reviewing this Crap?

http://practicalfragments.blogspot.com/2014/06/whos-reviewing-this-crap.html

This blog is meant to allow Fragment-based Drug Design Practitioners to get together and discuss NON-CONFIDENTIAL issues regarding fragments. Who's Reviewing this Crap? Dan and I teach a short course. On FBDD; next chance to catch a version in October. My favorite part of Dan's section is when he goes off on PAINS and the continuing pollution. Well, here is our first PAINS Shaming. This paper. Pointed out by Matt Netherton at B-I, thanks Matt! Because rhodanines as a class are known to often have activit...

practicalfragments.blogspot.com

Practical Fragments: Introducing the Chemical Probes Portal

http://practicalfragments.blogspot.com/2015/07/introducing-chemical-probes-portal.html

This blog is meant to allow Fragment-based Drug Design Practitioners to get together and discuss NON-CONFIDENTIAL issues regarding fragments. Introducing the Chemical Probes Portal. Chemical probes can be incredibly powerful reagents for understanding biology. A potent, selective, and cell-active modulator of a specific protein can be invaluable for figuring out what that protein actually does. Fragment-based methods can be effective at identifying these tool compounds, as we've described here. It should...

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The Importance of Chemistry in High-throughput Screening | This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS

The Importance of Chemistry in High-throughput Screening. This site is meant to allow HTS Practitioners to Share Non-Confidential Discussions about PAINS. Hoes show their pussy in public. PAINS in the Literature? PAINS, Not PAINS, or Promiscuous? September 6, 2014. Here we go again. Yes, 1-3. Lose activity when Triton is added to the assay. But why would 4. Have such similar activities under either conditions? Newest PAIN structure revealed. September 3, 2014. The newest PAINs structure on the block....

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