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FluTE Emulator ». FluTE Dissemination ». Surrogate modeling is relevant for many public health problems. We also analyzed the results from an economic evaluation described in van Hoek et al [2] to estimate the quality adjusted life year gain of varicella-zoster vaccination. Varicella Emulator ». Chao D., Halloran M., Obenchain V., Longini I. (2010) FluTE, a publicly available stochastic influenza epidemic simulation model. PLoS Comput Biol 6: e1000656.

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FluTE Emulator ». FluTE Dissemination ». Surrogate modeling is relevant for many public health problems. We also analyzed the results from an economic evaluation described in van Hoek et al [2] to estimate the quality adjusted life year gain of varicella-zoster vaccination. Varicella Emulator ». Chao D., Halloran M., Obenchain V., Longini I. (2010) FluTE, a publicly available stochastic influenza epidemic simulation model. PLoS Comput Biol 6: e1000656.
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https://idm.uantwerpen.be

FluTE Emulator ». FluTE Dissemination ». Surrogate modeling is relevant for many public health problems. We also analyzed the results from an economic evaluation described in van Hoek et al [2] to estimate the quality adjusted life year gain of varicella-zoster vaccination. Varicella Emulator ». Chao D., Halloran M., Obenchain V., Longini I. (2010) FluTE, a publicly available stochastic influenza epidemic simulation model. PLoS Comput Biol 6: e1000656.

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1

FluTE: Dissemination

http://www.idm.uantwerpen.be/policy.php

Dissemination to policy makers. Policy makers need clear recommendations on reactive strategies instead of estimates for R0 and vaccine efficacies. We can instantiate our emulator for FluTE with disease and vaccine data and present the effect of social and pharmaceutical measures with a particular selection of the emulator E.g., when an influenza strain is emerging with R. And vaccines are produced with a protection of 60%. We can formulate the following recommendations:. May result in a 55%.

2

Main

http://www.idm.uantwerpen.be/index.php

FluTE Emulator ». FluTE Dissemination ». Surrogate modeling is relevant for many public health problems. We also analyzed the results from an economic evaluation described in van Hoek et al [2] to estimate the quality adjusted life year gain of varicella-zoster vaccination. Varicella Emulator ». Chao D., Halloran M., Obenchain V., Longini I. (2010) FluTE, a publicly available stochastic influenza epidemic simulation model. PLoS Comput Biol 6: e1000656.

3

Varicella-Zoster: Emulator

http://www.idm.uantwerpen.be/varicellaQALY.php

We establish the power of our approach with a high dimensional model from van Hoek et al (2012) with correlated inputs to explore cost-effectiveness of varicella-zoster vaccination programs. With symbolic regression, we selected 12 driving parameters from the 185 inputs. Here, the interactive prediction plots for the gain in quality adjusted life years (QALYs) are shown (Legend). Change in Zoster reactivation in Varicella vaccinees versus non vaccinees (chi) (%).

4

FluTE: Emulator

http://www.idm.uantwerpen.be/fluteAR.php

FluTE is an individual-based model for influenza transmission with options for reactive vaccination strategies. We optimized the parameter space to observe the relation between vaccination coverage and cumulative clinical attack rate. The result is the following emulator based on the complex simulation model to obtain systems understanding and instant predictions for the attack rate. (Legend). The expected number of secondary infections caused by a primary infection in a fully susceptible population.

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FluTE Emulator ». FluTE Dissemination ». Surrogate modeling is relevant for many public health problems. We also analyzed the results from an economic evaluation described in van Hoek et al [2] to estimate the quality adjusted life year gain of varicella-zoster vaccination. Varicella Emulator ». Chao D., Halloran M., Obenchain V., Longini I. (2010) FluTE, a publicly available stochastic influenza epidemic simulation model. PLoS Comput Biol 6: e1000656.

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