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Centre for Population Health Sciences | About

http://www.cphs.mvm.ed.ac.uk/aboutCPHS

The University of Edinburgh College of Medicine and Veterinary Medicine. Deanery of Molecular, Genetic and Population Health Sciences. Centre for Population Health Sciences. We host several collaboarative centres:. The Centre for Research on Families and Relationships. The Asthma UK Centre for Applied Research. The Scottish Collaboration on Public Health Research and Policy. And also the Mackenzie Medical Centre, a General Practice surgery in Edinburgh. Centre for Research on Families and Relationships.

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All publications – Taylor Lab

http://taylor.igmm.ed.ac.uk/publications/all-publications

Evolutionary Genetics and Genomics. Metrics and 4-star publications. Institute for Genetics and Molecular Medicine. Page last updated on 07-Oct-2016. Bidirectional transcription marks accessible chromatin and is not specific to enhancers. Kumar Y, Bickmore WA, Taylor MS. 2016 doi: 10.1101/048629. Mutational Biases Drive Elevated Rates of Substitution at Regulatory Sites across Cancer Types. Kaiser VB, Taylor MS. 2016 doi: 10.1371/journal.pgen.1006207. 2016 doi: 10.1002/bies.201500192. Jubb AW, Young RS.

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Selected Publications – Taylor Lab

http://taylor.igmm.ed.ac.uk/category/publication/selected-publications

Evolutionary Genetics and Genomics. Metrics and 4-star publications. Institute for Genetics and Molecular Medicine. The frequent evolutionary birth and death of functional promoters in mouse and human. Young RS, Hayashizaki Y, Andersson R, Sandelin A, Kawaji H, Itoh M, Lassmann T, Carninci P FANTOM Consortium, Bickmore WA, Forrest AR, Taylor MS. Genome Research 2015. Lagging-strand replication shapes the mutational landscape of the genome. A promoter-level mammalian expression atlas.

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The evolution of gene regulation – Taylor Lab

http://taylor.igmm.ed.ac.uk/themes/3-the-evolution-of-gene-regulation

Evolutionary Genetics and Genomics. Metrics and 4-star publications. Institute for Genetics and Molecular Medicine. The evolution of gene regulation. Understanding how gene regulation evolves and the effect of DNA sequence changes in controlling when genes are switched on. Promoter sequences are rapidly evolving. The gain and loss of long-range regulatory elements. At the Human Genetics Unit and David Hume’s lab. At the Roslin Institute. Unlike at promoters, the turnover of binding sites for the gluc...

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Molecular, Genetic and Population Health Sciences | The University of Edinburgh

http://www.ed.ac.uk/schools-departments/molecular-clinical-medicine

Skip to main content. Molecular, Genetic and Population Health Sciences. Molecular, Genetic and Population Health Sciences. Molecular, Genetic and Population Health Sciences home. Molecular, Genetic and Population Health Sciences. Our research activities are largely based in the. Institute of Genetics and Molecular Medicine at the University of Edinburgh; the Usher Institute of Population Health Sciences and Informatics; and the Division of Pathology. We offer taught and online. Master of Family Medicine.

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Images and permissions – Taylor Lab

http://taylor.igmm.ed.ac.uk/resources/images-and-permissions

Evolutionary Genetics and Genomics. Metrics and 4-star publications. Institute for Genetics and Molecular Medicine. Images in this website are either generated by us or to the best of our knowledge we have appropriate permissions to use. Images generated by us are detailed below with corresponding reuse license details (typically the Creative Commons Attribution license. Permitting free reuse on condition of acknowledgement. If this license doesn’t suit your needs, please get in touch.

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Alumni – Taylor Lab

http://taylor.igmm.ed.ac.uk/alumni

Evolutionary Genetics and Genomics. Metrics and 4-star publications. Institute for Genetics and Molecular Medicine. Sophie Marion de Procé. Dr Sophie Marion de Procé. Sophie is now working with Prof. Tim Aitman. Still at the Institute of Genetics and Molecular Medicine. [ more. Research Associate (joint with Andrew Jackson). Mihail is now working with Prof Colin Semple. In a translational bioinformatics post, still at the Institute of Genetics and Molecular Medicine. And has made her software SuRFR.

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Interpretation of genetic variation – Taylor Lab

http://taylor.igmm.ed.ac.uk/themes/2-the-interpretation-of-contemporary-genetic-variation

Evolutionary Genetics and Genomics. Metrics and 4-star publications. Institute for Genetics and Molecular Medicine. Interpretation of genetic variation. Which DNA changes contribute to meaningful differences between individuals such as disease state or disease risk, and which are of little consequence? Identifying disease mutations and functional variants.

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Books – Taylor Lab

http://taylor.igmm.ed.ac.uk/publications/books

Evolutionary Genetics and Genomics. Metrics and 4-star publications. Institute for Genetics and Molecular Medicine. C) Taylor and Francis. Permission requested. Comparative genomics and mammalian promoter evolution. Jordan G, Semple CA. Understanding transcriptional networks with cap analysis of gene expression (CAGE). Edited by Carninci P) 2009 ISBN: 978-4241-34-2. Edited by Barnes M). 2007 Wiley Press. ISBN: 978-0-470-02619-9. Bioinformatics – From Genomes to Therapies.