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Insulin is hard (but not impossible) | indysci.org blog

http://blog.indysci.org/insulin-is-hard-but-not-impossible

Insulin is hard (but not impossible). June 13, 2015 12:00 am. As I worked on insulin in grad school, I risked my job as a lowly postdoc, chiming in and pointedly telling him (in front of the program manager) why it wouldn’t work. Some of my coworkers speculated that I might not show up the next day, but I survived to tell the tale. Since the idea of homebrewing insulin. In the words of a co-grad student of mine, who went on to work at Eli Lilly in their insulin department, insulin is a bitch of a molecul...

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indysci.org blog | Page 6

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January 10, 2014 10:07 pm. We soft-launched bitcoin donations. Earlier this month (our ‘main’ launch will occur after we get 501(c)(3) status) – after coindesk ran an article. About us accepting bitcoins. So far we’ve gotten a little over 3 BTC, which is almost a third of the way towards our goal of making a compound and calling it satoshimycin! I have some things to say about the economics of bitcoin and why bitcoin donors are generous, will be collecting my thoughts on the matter soon. So I’m goi...

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patents | indysci.org blog

http://blog.indysci.org/category/patents

An Open Letter to Richard Posner. December 10, 2013 12:00 am. Dear Judge Posner,. I am writing this open letter to solicit a donation from you for my nonprofit organization. indysci dot org is organized to conduct basic and applied science research. More to the point, our first project is to bring an unpatented. Anticancer drug candidate through preclinical trials. Today is significant because the Supreme court is hearing arguments in. Alice v. CLS. Isaac Yonemoto, PhD. Founder, indysci dot org. There ar...

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crowdfunding | indysci.org blog

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On Crowdfunding Science II. February 17, 2014 11:05 pm. Disclaimer: I run an organization that has attempted science crowdfunding. And failed) and intends to relaunch using crowdfunding later this year, and I have personally contributed a small sum ($25) to the Immunity Project. Science is the belief in the ignorance of experts. Richard P. Feynman. This is a response to “Crowd-funded HIV vaccine project sparks a debate”. Featured in Nature News. Read More →. September 29, 2013 10:52 pm. Read More →.

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philosophy | indysci.org blog

http://blog.indysci.org/category/philosophy

March 17, 2014 1:26 pm. In December, another researcher contacted me with questions about the 9DS paper. He wanted to do some derivative research on the topic) and while carefully parsing the paper we noticed that in the methods section the ratio “DNA:PBD = 1:20” is incorrect, it should have been “DNA:PBD = 20:1” or alternatively “PBD:DNA = 1:20”. So the question is, is it a transcribing error, either when I wrote it down in my notebook, or when I transferred notebook to manuscript? In terms of indysci&#...

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indysci.org blog | Page 3

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Insulin is hard (but not impossible). June 13, 2015 12:00 am. As I worked on insulin in grad school, I risked my job as a lowly postdoc, chiming in and pointedly telling him (in front of the program manager) why it wouldn’t work. Some of my coworkers speculated that I might not show up the next day, but I survived to tell the tale. Since the idea of homebrewing insulin. Read More →. Starting a lab under-budget. May 25, 2015 4:48 am. I’m excited to report to the donors (and the public! I wasn’t sure...

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lab report | indysci.org blog

http://blog.indysci.org/category/lab-report

Category Archives: Lab Report. 2015 Project Marilyn Budget Transparency Report. April 5, 2016 6:00 am. As promised, here is Project Marilyn’s 2015 budget. In it you can get a general idea how much it costs to run a science lab on a bare-bones budget. Https:/ docs.google.com/spreadsheets/d/1tSMV9DrsVcuS3J0zxfiKkbmXPnejSjZ9ZxSsCOWuadc/edit#gid=0. January 23, 2016 2:25 am. If you want to skip directly to the donate link, go here. You should read the whole thing. Luckily, this is a relatively easy process; t...

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bitcoin | indysci.org blog

http://blog.indysci.org/category/bitcoin

January 23, 2016 2:25 am. If you want to skip directly to the donate link, go here. You should read the whole thing. As part of fundraising using bitcoin, I promised that if I raised more than 10 BTC (I got a bit more than 11 BTC total), I’d start testing other molecules in the 9DS family, one of which would be named “Satoshimycin”. Why do we want more compounds? Especially since within the 9DS family, the infrastructure and strategies are shared. Read More →. 2015 in Project Marilyn. To save on rent, I ...

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isaac | indysci.org blog

http://blog.indysci.org/author/admin

Days 2 & 3). June 22, 2016 7:37 am. Sorry for the delayed post! What happened on Days 2 and 3 was that there was a serious yeast contamination in the cultures set up! Why this happens: Sometimes, the bacterial strain loses its ability to make the drug 9DS: The genes that make 9DS are turned down. Because 9DS fumagates the culture and keeps fungi from growing, when this happens, yeast can contaminate the media and grow. Day 3: Observation of plate showed no positive cultures. June 14, 2016 7:29 pm. And so...

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Starting a lab under-budget | indysci.org blog

http://blog.indysci.org/starting-a-lab-under-budget

Starting a lab under-budget. May 25, 2015 4:48 am. You may have been seeing photographs of equipment and supplies coming into the lab via the Project Marilyn Facebook Page. I’m excited to report to the donors (and the public! The story behind this. The most expensive item. Which is dedicated to removing the friction involved in ordering lab supplies for biology startups. And in some cases, directly requesting special deals. Many research organizations have staff dedicated to ordering, who have specia...