A summary of BRCA1, a gene associated with breast and ovarian cancer. Summary of phylogeny, gene and protein, and analysis of popular articles and their primary article counterparts.
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BRCA1 - Introduction | kueckgen677s09.weebly.com Reviews
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A summary of BRCA1, a gene associated with breast and ovarian cancer. Summary of phylogeny, gene and protein, and analysis of popular articles and their primary article counterparts.
kueckgen677s09.weebly.com
News vs. primary literature - BRCA1
http://kueckgen677s09.weebly.com/news-vs-primary-literature.html
In the primary literature. News vs. primary literature. Comparison of popular press and primary literature. Site created by Jessica D. Kueck. Assignment, Spring 2009. Create a free website. Create your own free website. Start your own free website. A surprisingly easy drag and drop site creator. Learn more.
Protein - BRCA1
http://kueckgen677s09.weebly.com/protein.html
In the primary literature. News vs. primary literature. Human BRCA1 protein sequence. Protein size: 1861 amino acids (aa). Accession number: NP 009225.1. This isoform was chosen because it is most frequently occurring transcript. 10 other variants have been described ( Entrez. The following file shows the sequence in FASTA format. Homo sapiens brca1 isoform 1.docx. Similarity of protein sequences of human BRCA1 protein to proteins in other organisms evolved from a common ancestral gene.
BRCA1 - Introduction
http://kueckgen677s09.weebly.com/index.html
In the primary literature. News vs. primary literature. According to breastcancer.org. 1 in 8 women will develop breast cancer in their lifetime. SEER. Is a gene associated with human breast and ovarian cancer susceptibility, which is where its full name comes from: breast cancer-1, early onset. Mutations in this gene are found in familial, early-onset cases of breast cancer. Current estimates on the number of inherited breast cancer cases related to BRCA1. Though the frequency of BRCA1. Mutations varies...
Organism phenotypes - BRCA1
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In the primary literature. News vs. primary literature. In humans, mutations in BRCA1. Clearly lead to breast cancer and ovarian cancer. What kinds of phenotypes are found in other organisms. Most of what I have focused on is in model organisms less closely related to humans. Use of siRNA to somewhat transiently knock down gene expression in smaller organisms. Tests for small molecules that inhibit all or specific functions of a protein, or may be activating. Site created by Jessica D. Kueck.
Gene - BRCA1
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In the primary literature. News vs. primary literature. Full gene name: breast cancer 1, early onset. Gene length: 81,155 bp. Number of exons: 23 (1-3, 5-24). Accession number: NC 000017.9. The following file shows the sequence in FASTA format. Brca1 gene sequence.docx. Genes evolved from a common ancestor, and the similarity between their coding sequences. Trees showing relatedness between BRCA1 gene homologs based on gene sequence. Gene expression and microarrays. Site created by Jessica D. Kueck.
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BRCA1 - Introduction
In the primary literature. News vs. primary literature. According to breastcancer.org. 1 in 8 women will develop breast cancer in their lifetime. SEER. Is a gene associated with human breast and ovarian cancer susceptibility, which is where its full name comes from: breast cancer-1, early onset. Mutations in this gene are found in familial, early-onset cases of breast cancer. Current estimates on the number of inherited breast cancer cases related to BRCA1. Though the frequency of BRCA1. Mutations varies...
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