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Small haplotypes indicate ancient mutations

Deciphering the mosaic pattern of haplotypes observed around a single mutation is a terrible challenge.

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Small haplotypes indicate ancient mutations | mathuselah.com Reviews

https://mathuselah.com

Deciphering the mosaic pattern of haplotypes observed around a single mutation is a terrible challenge.

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1

What is the goal of the Mathuselah project?

http://www.mathuselah.com/graph-theory/genetics/about-Mathuselah.htm

The reconstruction of mutation genealogies from present-day chromosomes can provide us with information about past events. Moving backwards in time is a fascinating goal owing to the sharp contrast between the simplicity. Of the question and the extreme difficulty of conducting backward statistical reconstruction of genealogies from observed haplotypes. If we wish to obtain an image of ancestral genealogies with a useful degree of precision, we need an algebraic description.

2

Collaborative projects in statistical and population genetics

http://www.mathuselah.com/who/author.htm

My primary research interests are in statistical and population genetics. My current goal is the algebra of haplotype decay, related to the graphs. Representing the ancestry of a mutation. Genealogies of intermediate complexity have algebraic solutions, bridging the gap between haplotype size and genealogical models. Marc Jeanpierre, 2016, mail.

3

A graph with the topology of a star

http://www.mathuselah.com/graph-theory/Bayesian-networks/star-graph.htm

The resolution of time intervals for possible population expansions requires the demonstration. Of star genealogies rather than their prior assumption. What remains from one branch is. From the others, and the compound distribution is the product of individual branches. Star-like genealogies are by far the easiest to analyze, as this model bypasses all the difficulties of translating a set of mosaic haplotypes into a specific genealogy.

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Small haplotypes indicate ancient mutations

Deciphering the mosaic pattern of haplotypes observed around a single mutation is a difficult challenge. When modeling of the decay of haplotype sharing, simple. Geometric structures that can be described unambiguously in mathematical terms can provide an algebraic framework. For analyses of the forces shaping the genealogy of a single allele. Written by Marc Jeanpierre.

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