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McCague Scientific Consulting

Elcome to the Web-Site of McCague Scientific Consulting. Helping to solve your challenges in life-science chemistry and related scientific matters. For a summary of the contents of this site, hover the cursor down the various tabs below (when this page has fully loaded). Please use the links on the left to access the various pages of this site. Approved drugs and clinical pipeline compounds are tracked, allowing correlations of therapeutic characteristics with chemical structure. Tel 44 1954 211122.

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Elcome to the Web-Site of McCague Scientific Consulting. Helping to solve your challenges in life-science chemistry and related scientific matters. For a summary of the contents of this site, hover the cursor down the various tabs below (when this page has fully loaded). Please use the links on the left to access the various pages of this site. Approved drugs and clinical pipeline compounds are tracked, allowing correlations of therapeutic characteristics with chemical structure. Tel 44 1954 211122.

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1 scientific

2 consulting

3 crystallisation

4 crystallization

5 chiral

6 technology

7 resolution

8 purification

9 synthesis

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McCague Scientific Consulting | mcc-sci.com Reviews

https://mcc-sci.com

Elcome to the Web-Site of McCague Scientific Consulting. Helping to solve your challenges in life-science chemistry and related scientific matters. For a summary of the contents of this site, hover the cursor down the various tabs below (when this page has fully loaded). Please use the links on the left to access the various pages of this site. Approved drugs and clinical pipeline compounds are tracked, allowing correlations of therapeutic characteristics with chemical structure. Tel 44 1954 211122.

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mcc-sci.com

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www.mcc-sci.com: Site Map

http://www.mcc-sci.com/site_map.htm

Hellip; … Solid-Solution Theory. Hellip; … Entrainment Theory. Hellip; … Resolution Calculator. Hellip; … Purification Calculator. Hellip; Synthesis Technology. Hellip; … Chiral Technology. Hellip; … Organic Synthesis. Hellip; … Route and Process Design. Hellip; Pharmaceutical Profiling. Hellip; Intellectual Property.

2

www.mcc-sci.com: Entrainment Theory

http://www.mcc-sci.com/entrainment_theory.htm

Theory for Modelling Resolution by Entrainment. Theory for Mathematical Modelling. Examples of Mathematical Modelling. Entrainment of a crystallisation may be useful in various circumstances and development of an entrainment process may be assisted by reference to a mathematical model. The following scenarios of increasing complexity may be considered:. Single compound A with two crystal forms A1 and A2, entrained by A1. Two compounds A and B, each with one crystal form and entrained by A. A twinning par...

3

www.mcc-sci.com: Crystallisation

http://www.mcc-sci.com/crystallization.htm

Kinetic Entrainment and Crystal Twinning. In order to understand a crystallisation-based resolution or purification requires consideration of several possible scenarios, limitations in the solid-state physical chemistry, or other eventualities, some of the more important of which are listed below. Advice on these can be provided through consultancy, particularly noting that the concepts overlap and there is benefit in considering several of the topics simultaneously for a given crystallisation problem.

4

www.mcc-sci.com: Organic Synthesis

http://www.mcc-sci.com/organic_synthesis.htm

In addition to a background of around 25 years experience in organic synthesis, both in medicinal chemistry and process R&D, the service in organic synthesis benefits from a database of innovative synthetic methods classified by (a) the lead-researcher, and (b) the type of reaction or technology. In the past year, some general observations of developments in the organic synthesis methodology field are:. The rise in methods of organocatalysis (i.e using a catalyst that contains no metal atoms) and wit...

5

www.mcc-sci.com: Intellectual Property

http://www.mcc-sci.com/intellectual_property.htm

Scientific Intellectual Property Support. Support to intellectual property development can be given in areas of process technology and pharmaceutical chemistry. The following are offered:. Construction of a patent specification from background and experimental descriptions. Assistance with the construction of patent-claim sets, or revision of claims based on examiners' feedback. Advice on the consolidation of a patent application prior to international filing. Expert advice and opinion.

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parkplaceresearch.co.uk

Park Place Research: Process Simulation

http://parkplaceresearch.co.uk/process_simulation.html

Park Place Research now offers a fully integrated service in Process Optimisation. This combines expertise in automated process characterisation, process analytical technology (PAT) and process engineering expertise, the latter through HFL-Park Place. The joint venture formed with Haden Freeman Engineering Group in 2006. Now additional strength to this offering is made through the inclusion of mathematical modelling-based process simulation via an alliance with McCague Scientific Consulting.

parkplaceresearch.com

Park Place Research: Process Simulation

http://www.parkplaceresearch.com/process_simulation.html

Park Place Research now offers a fully integrated service in Process Optimisation. This combines expertise in automated process characterisation, process analytical technology (PAT) and process engineering expertise, the latter through HFL-Park Place. The joint venture formed with Haden Freeman Engineering Group in 2006. Now additional strength to this offering is made through the inclusion of mathematical modelling-based process simulation via an alliance with McCague Scientific Consulting.

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mcc-sci.com

McCague Scientific Consulting

Elcome to the Web-Site of McCague Scientific Consulting. Helping to solve your challenges in life-science chemistry and related scientific matters. For a summary of the contents of this site, hover the cursor down the various tabs below (when this page has fully loaded). Please use the links on the left to access the various pages of this site. Approved drugs and clinical pipeline compounds are tracked, allowing correlations of therapeutic characteristics with chemical structure. Tel 44 1954 211122.

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