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McCombie Lab |

Cold Spring Harbor Laboratory. Human genetics; human genome variation; personal genomics; genetics of psychiatric disorders; genetics of cancer, computational molecular biology. See all lab members. We also have an active program in plant genomics. Here we are focused on using new strategies and technologies to carry out de novo.

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McCombie Lab | | mccombielab.labsites.cshl.edu Reviews
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Cold Spring Harbor Laboratory. Human genetics; human genome variation; personal genomics; genetics of psychiatric disorders; genetics of cancer, computational molecular biology. See all lab members. We also have an active program in plant genomics. Here we are focused on using new strategies and technologies to carry out de novo.
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McCombie Lab | | mccombielab.labsites.cshl.edu Reviews

https://mccombielab.labsites.cshl.edu

Cold Spring Harbor Laboratory. Human genetics; human genome variation; personal genomics; genetics of psychiatric disorders; genetics of cancer, computational molecular biology. See all lab members. We also have an active program in plant genomics. Here we are focused on using new strategies and technologies to carry out de novo.

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mccombielab.labsites.cshl.edu mccombielab.labsites.cshl.edu
1

McCombie Lab | Cognitive Genomics

http://mccombielab.labsites.cshl.edu/cognitive-genomics

This work is done as part of the Stanley Center for Cognitive Genomics. At Cold Spring Harbor Laboratory. Nature, 515(7526) pp. 216-221. Molecular Psychiatry, 19(6) pp. 652-658. Molecular Psychiatry, 19(6) pp. 668-675. McCarthy, S. E. and McCombie, W. R. and Corvin, A. (2014) Unlocking the Treasure Trove: From Genes to Schizophrenia Biology. Neuron, 74(2) pp. 285-299. Nature Genetics, 39(12) pp. 1522-7.

2

McCombie Lab | Plant Genomics

http://mccombielab.labsites.cshl.edu/plant-genomics

The combination of climate change, rapidly growing population, and urbanization are creating tremendous stress on the planet’s ability to provide enough food for everyone. A better understanding of how plants grow, develop and reproduce at the basic level will be critical for addressing this challenge. Understanding the genomes of plants will play a critical role in achieving these goals. Plant genomes we have studied:. Nature, 491(7426) pp. 705-710. Nature, 485(7400) pp. 635-41. Rabinowicz, P. D&#46...

3

McCombie Lab | Cancer Genomics

http://mccombielab.labsites.cshl.edu/cancer-genomics

Oncogene, 33(3) pp. 347-57. Nature, 472(7341) pp. 90-94. Cancer Cell, 16(4) pp. 324-35. Cell, 135(5) pp. 852-864. Burgess, D. J. and Doles, J. and Zender, L. and Xue, W. and Ma, B. and McCombie, W. R. and Hannon, G. J. and Lowe, S. W. and Hemann, M. T. (2008) Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc Natl Acad Sci U S A, 105(25) pp. 9053-9058. Cancer Cell, 3(3) pp. 297-302. Nature, 409(6817) pp. 207-211. Science, 275(5308) pp. 1943-7.

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McCombie Lab | Publications

http://mccombielab.labsites.cshl.edu/publications

5

McCombie Lab | People

http://mccombielab.labsites.cshl.edu/people

PhD, University of Michigan, 1982. Res Invest/Project Mgr, CCG. Dir, Admin, Human Gen Ctr. Computational Sci. Developer I. Computational Sci. Analyst III. Mavruk Eskipehlivan, Senem. McCarthy, Shane Edward. Mendivil Ramos, Olivia. Lab Tech I,Illumina Sequencing. Scientific Admin. Assistant. Manager, Lab Facility.

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Cold Spring Harbor Laboratory. Human genetics; human genome variation; personal genomics; genetics of psychiatric disorders; genetics of cancer, computational molecular biology. See all lab members. We also have an active program in plant genomics. Here we are focused on using new strategies and technologies to carry out de novo.

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