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Dr. Amedeo Blog: Leaky Protons
http://dramedeo-amedeo.blogspot.com/2011/10/leaky-protons.html
Saturday, October 15, 2011. REFERENCE: Alavian et al. “Bcl-X. Regulated metabolic efficiency of neurons through interaction with the mitochondrial F. ATP synthase” Nature Cell Biology (2011) 13(10) pgs 1224 – 1233. B-cell lymphoma-extra large ( Bcl-X. A member of the programmed cell death Bcl-2 family proteins, is the major anti-apoptotic protein in adult neurons. When Bcl-X. In these events is not clear. In this month’s edition of Nature Cell Biology. Alavian et al. detail a role for Bcl-X. Fluorescent ...
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Dr. Amedeo Blog: June 2012
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Monday, June 11, 2012. Crystallography: phasing out heavy atom derivatives. REFERENCE: Liu et al. "Structures from Anomalous Diffraction of Native Biological Macromolecules." Science (2012) 336, pgs 1033 - 1037. The field of protein crystallography has partially pulled back the veil that lies between the macroscopic and microscopic worlds. Each spot on a diffraction pattern arises from a constructive interference event between X-ray waves within the protein crystal. Liu et al. discuss their new techn...
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Dr. Amedeo Blog: November 2011
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Monday, November 28, 2011. American Society for Cell Biology Meeting. Denver, CO: December 3. Saturday) – December 7. REFERENCE: Science (2011) 334 pgs 1046 - 1051. This Saturday marks the beginning of the annual ASCB meeting in Denver, CO. The event will feature over 3000 scientific poster presentations as well as 100 scientific sessions. Principal Investigators, post doctoral associates and graduate students from all over the world will descend on Denver to discuss science ( and ski. Some cells make up...
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Smarts and Crafts: October 2011
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Saturday, October 29, 2011. My husband and I married on a deck over the ocean. It was perfectly beautiful. We had ten guests. I think we had two rows of three chairs on each side to make an “aisle.” In the months leading up to the wedding, I was becoming upset about the lack of aisle definition. I know that is a really ridiculous thing to become fixated on, but yet, I couldn’t shake the idea. I discussed with lots of people how to define the aisle. Bear in mind some parameters:. I was at a total loss....
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Smarts and Crafts: November 2011
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Saturday, November 26, 2011. Easy Peasy Banana Bread. In the days BB ( before breadmaker. I didn’t make any bread but this recipe. It was quick, easy, required no kneading or rising, and was a great use for black bananas. Considering I don’t eat bananas once they get a bruise or run past the slightly green/bright yellow stage, this recipe saved a lot of bananas from a garbage fate. 3 – 4 ripe/black bananas. 1/3 cup melted butter. 1/3 – ¾ cup of sugar *. 1 egg, beaten. 1 tsp baking soda. Instead, I’...
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Smarts and Crafts: January 2012
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Saturday, January 28, 2012. This post isn’t meant to showcase a truly awesome cake à. La Cake Boss, Ace of Cakes or Food Network Challenge. Please, I don’t know how to build cakes! It’s just meant to show a cute technique that I’ve used to make a fun little cake. I made this cake for a baby shower several years ago. Two girls I worked with were having babies and I love them both. I wanted to make them an awesome cake. I frosted the entire thing with buttercream. Curl your right hand into a fist. Foggy mi...
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Amedeo Blog: April 2012
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Saturday, April 14, 2012. You use that in lab? Forgive me, but I’m continuing through a busy busy time both in my life and in lab so posts are a bit sporadic and not on topic. I’ve read several ageing papers and will get to writing those up soon, but since it has been so long since my last post, I needed something quick! I was oddly inspired for this post today while I was rushing to make a post doc ethics meeting ( no jealousy, please. What inspired me exactly? My nail polish is missing. I have a few!
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Amedeo Blog: May 2012
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Saturday, May 19, 2012. Everyone wants to be noble. Let’s look at an example of how a model is built. Facts. Amy spent her day at the park, then had a dinner of steak and mushrooms. Following her dinner, she developed hives. She would like a model to explain what caused the hives. Experiments. And basically everything that happens at the level of atoms, molecules, cells, organs, etc. Scientists labeled them as such after they discovered that, no matter how they tried, these gases simply would not form mo...
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Amedeo Blog: The Central Dogma (Biochemistry)
http://amedeo-amedeo.blogspot.com/2011/03/central-dogma.html
Wednesday, March 2, 2011. The Central Dogma (Biochemistry). The central dogma of molecular biology is nearly summed up in that small diagram. ( I’ll explain why I say “nearly” at the end of this post. So, what in the world does it mean? To explain why certain things and activities are placed where they are. An overview of this analogy is given in Figure 4.1. Let’s start with a guided tour of a cell. Figure 4.2. 8211; anything inside the plasma membrane is inside the cell. Which carry out almost all of th...
