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IMPC | International Mouse Phenotyping Consortium

International Mouse Phenotyping Consortium. References using IKMC and IMPC Resources. Produce and phenotype knockout mouse lines for 20,000 genes. What does IMPC do? How does IMPC work? How to cite this resource? January 17, 2018. New diabetes genes discovered in latest IMPC research. September 1, 2017. Novel hearing loss genes identified in large study by scientists across the world. June 26, 2017. Study of unprecedented size reveals how *** ‘blindspot’ could misdirect medical research. Systematic broad...

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IMPC | International Mouse Phenotyping Consortium | mousephenotype.org Reviews
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International Mouse Phenotyping Consortium. References using IKMC and IMPC Resources. Produce and phenotype knockout mouse lines for 20,000 genes. What does IMPC do? How does IMPC work? How to cite this resource? January 17, 2018. New diabetes genes discovered in latest IMPC research. September 1, 2017. Novel hearing loss genes identified in large study by scientists across the world. June 26, 2017. Study of unprecedented size reveals how *** ‘blindspot’ could misdirect medical research. Systematic broad...
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4 impc publications browser
5 phenoview
6 rest api
7 other tools
8 about impc
9 objectives and background
10 impc members
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IMPC | International Mouse Phenotyping Consortium | mousephenotype.org Reviews

https://mousephenotype.org

International Mouse Phenotyping Consortium. References using IKMC and IMPC Resources. Produce and phenotype knockout mouse lines for 20,000 genes. What does IMPC do? How does IMPC work? How to cite this resource? January 17, 2018. New diabetes genes discovered in latest IMPC research. September 1, 2017. Novel hearing loss genes identified in large study by scientists across the world. June 26, 2017. Study of unprecedented size reveals how *** ‘blindspot’ could misdirect medical research. Systematic broad...

INTERNAL PAGES

mousephenotype.org mousephenotype.org
1

iMits - Home

http://www.mousephenotype.org/imits

Contacts for Production Centres. Download of all Production. Welcome to International Micro-Injection Tracking System. iMITS is the designated database for the planning of all IMPC mouse production,. As well as the central database to allow IMPC production centres to record the progress of mouse production, cre-excision and to summarise. The progress of phenotype data collection and transfer to the IMPC DCC. All IMPC data (especially phenotyping data) can be found on the IMPC website. Genes with ES cells.

2

Coordination | IMPC

http://www.mousephenotype.org/about-impc/coordination

International Mouse Phenotyping Consortium. References using IKMC and IMPC Resources. The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Panel of Scientific Consultants. Data Analysis Advisory Committee. MTA and Line Exchange. Release : 4.3.

3

Communications Materials | IMPC

http://www.mousephenotype.org/my-impc/communications-materials

International Mouse Phenotyping Consortium. References using IKMC and IMPC Resources. If you are a member of the IMPC, you can download and use the IMPC communications resources provided below. There is also a quarterly IMPC newsletter. Please get in touch via the website feedback email link on the contact page if you would like editable versions of any of these (e.g. for translation) or to request any additional communications materials. IMPC Summary Slide.pptx. IMPC Flyer final.pdf. Release : 4.3.

4

EUCOMM | IMPC

http://www.mousephenotype.org/about-ikmc/eucomm

International Mouse Phenotyping Consortium. References using IKMC and IMPC Resources. The European Conditional Mouse Mutagenesis Program is founder member and European cornerstone of the International Knockout Mouse Consortium (IKMC). Contributes the largest fraction of conditionally trapped and targeted genes in mouse C57BL/6N embryonic stem (ES) cells to the IKMC. Mutant ES cells and vectors can be obtained from the European Mouse Mutant Cell Repository (EuMMCR). EUCOMM Farewell Meeting Participants.

5

eucommtools | IMPC

http://www.mousephenotype.org/about-ikmc/eucommtools

International Mouse Phenotyping Consortium. References using IKMC and IMPC Resources. EUCOMMTOOLS - EUCOMM: Tools for Functional Annotation of the Mouse Genome - is successor project of EUCOMM and member of the International Knockout Mouse Consortium (IKMC). EUCOMMTOOLS will complete the IKMC resource of mutations for all protein coding genes. Furthermore, EUCOMMTOOLS will maximize the utility of the conditional IKMC resource by generating up to 250 different, mostly inducible Cre driver mouse lines.

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emma.cnr.it emma.cnr.it

CNR-EMMA Monterotondo

http://emma.cnr.it/CNR-Monterotondo.html

Consiglio Nazionale delle Ricerche. A Buzzati-Traverso" Campus, Monterotondo. The co-ordinating Institution of the EMMA Core Structure. The EMMA Core Structure at Monterotondo. The Consiglio Nazionale delle Ricerche (CNR; Italian National Research Council) has established and coordinates the Core Structure of the EMMA (European Mouse Mutant Archive) Network Infrastructure and the new Mouse Clinic facility, at the "A. Buzzati-Traverso" Internazional Campus in Monterotondo (Rome, Italy). Is specifically or...

informatics.jax.org informatics.jax.org

Gene Expression Literature Search

http://www.informatics.jax.org/gxdlit

Search for genome features by name, symbol, synonym, homolog, allele, or accession ID:. P53 protein cell cycle DNA damage. Search for genome features and vocabulary terms by keywords or accession ID. Use several keywords to find the most relevant results:. Resistance to fatty liver development. Lymphocyte function antigen immunodeficiency. Use asterisks (*) for wildcards at the end of partial words or genomic symbols:. Hippocamp* pyramid* cell layer. Use quotation marks to indicate phrases:. Internation...

norcomm2.org norcomm2.org

NorCOMM2 - Phenotyping - Project

http://www.norcomm2.org/norcomm2/index.php

Get the data you need for grant proposals, or explore gene function for gene candidates for disease, development, or drug target validation here. Genes passing ES cell QC. Genes in cohort production. NorCOMM2 contributes to an International Mouse Phenotyping Consortium. That will functionally annotate all 20,000 genes of the mammalian genome in the next 10 years (more info). NorCOMM2 will generate and phenotype 150 new knock-out mouse lines at TCP. Are nominated by Canadian scientists. L About Nor COMM.

monarch-initiative.blogspot.com monarch-initiative.blogspot.com

Monarch Initiative: November 2014

http://monarch-initiative.blogspot.com/2014_11_01_archive.html

Enabling navigation across a rich landscape of phenotypes, diseases, models, and genes for translational research. Saturday, November 29, 2014. IMPC mouse knockout model phenotypes added. We have added phenotype data from the International Mouse Phenotyping Consortium. IMPC data is presently accessible in the Monarch portal via Mouse gene pages (for example, Stk16. Or via phenotypic similarity comparison on disease pages (such as Sebastian Syndrome. Or Susceptibility to Malignant Hyperthermia 3.

phenomin.fr phenomin.fr

Scientific context | PHENOMIN

http://www.phenomin.fr/scientific-context/workpackages

Genetic Engineering and Model Validation. Ethics and animal welfare. WP2: Genetic Engineering and Model Validation. Some of the resources to be developed under WP2 will also be of interest for pharmaceutical or biotech companies and will thus provide additional funding for the nodes. Phenotyping protocols will be transferred to PhenoPro to extend the offer of this ICS spin out. Two main scientific achievements are anticipated:. To develop innovative and pertinent genetic tools for the scientific community.

phenomin.fr phenomin.fr

Scientific context | PHENOMIN

http://www.phenomin.fr/scientific-context/collaborations

Genetic Engineering and Model Validation. Ethics and animal welfare. AgedBrainSYSBIO - System biology of pathways involving brain aging. Http:/ www.agedbrainsysbio.eu/. BPI FRANCE MAGENTA: Innovative animal models for the discovery of candidate genes to the validation of therapeutic molecules for genito-urinary disorders. Http:/ www.excellence.bpifrance.fr/. European Framework Programme H2020 supports CanPathPro project, a unique and innovative platform for predictive modelling of cancer signaling. TEFOR...

phenomin.fr phenomin.fr

Rare Diseases | PHENOMIN

http://www.phenomin.fr/rare-diseases

Genetic Engineering and Model Validation. Ethics and animal welfare. Mouse Models for Rare Diseases. Successful long term collaborations with French and European partners ( Fondation maladies rares. Allowed generation of customed mouse models for researchers. Investigating gene function and human pathophysiology. More than 50 mouse rare disease models are now available for your research. For more details concerning the alleles, please contact us. By orthologous gene and by shared phenotypic features.

phenomin.fr phenomin.fr

Calls for proposals | PHENOMIN

http://www.phenomin.fr/calls/previous-calls

Genetic Engineering and Model Validation. Ethics and animal welfare. We are glad to announce the new PHENOMIN call dedicated to generation and characterization of CreER T2. Cell specific promoter driven deleter mouse lines. Since 2011, PHENOMIN has generated more than 150 models with conditional potential. In the frame of the International Mouse Phenotyping Consortium (IMPC). More than 5,000 genes are already committed to the IMPC pipeline. Most of these models can be driven in conditional alleles. Lines...

phenomin.fr phenomin.fr

Calls for proposals | PHENOMIN

http://www.phenomin.fr/calls

Genetic Engineering and Model Validation. Ethics and animal welfare. We are glad to announce the new PHENOMIN call dedicated to generation and characterization of CreER. Cell specific promoter driven deleter mouse lines. Since 2011, PHENOMIN has generated more than 150 models with conditional potential. In the frame of the International Mouse Phenotyping Consortium (IMPC). More than 5,000 genes are already committed to the IMPC pipeline. Most of these models can be driven in conditional alleles. Which in...

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IMPC | International Mouse Phenotyping Consortium

International Mouse Phenotyping Consortium. References using IKMC and IMPC Resources. Produce and phenotype knockout mouse lines for 20,000 genes. What does IMPC do? How does IMPC work? How to cite this resource? January 17, 2018. New diabetes genes discovered in latest IMPC research. September 1, 2017. Novel hearing loss genes identified in large study by scientists across the world. June 26, 2017. Study of unprecedented size reveals how sex ‘blindspot’ could misdirect medical research. Systematic broad...

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