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MRC Mitochondrial Biology Unit | the involvement of mitochondria and their dysfunction in an ever-increasing range of human diseases

Skip to main content. Annual Sir John Walker Lecture. Thursday, 22 February 2018. Sunday, 25 March 2018. Transfer into University of Cambridge. Wednesday, 21 June 2017. Who are we and what do we research? Introduction from the Director. Research at the MRC Mitochondrial Biology Unit. List of Unit publications. Mitochondria: Power houses, factories, waste disposal and recycling centres, and assassins. Genetic modification of the mitochondrial genome. The mitochondrial proteome (IMPI). On Sunday, 25 March ...

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MRC Mitochondrial Biology Unit | the involvement of mitochondria and their dysfunction in an ever-increasing range of human diseases | mrc-mbu.cam.ac.uk Reviews
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Skip to main content. Annual Sir John Walker Lecture. Thursday, 22 February 2018. Sunday, 25 March 2018. Transfer into University of Cambridge. Wednesday, 21 June 2017. Who are we and what do we research? Introduction from the Director. Research at the MRC Mitochondrial Biology Unit. List of Unit publications. Mitochondria: Power houses, factories, waste disposal and recycling centres, and assassins. Genetic modification of the mitochondrial genome. The mitochondrial proteome (IMPI). On Sunday, 25 March ...
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2 search form
3 director's introduction
4 what are mitochondria
5 mitochondrial animations
6 mitochondrial disease
7 history
8 alumni
9 our patron
10 research
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MRC Mitochondrial Biology Unit | the involvement of mitochondria and their dysfunction in an ever-increasing range of human diseases | mrc-mbu.cam.ac.uk Reviews

https://mrc-mbu.cam.ac.uk

Skip to main content. Annual Sir John Walker Lecture. Thursday, 22 February 2018. Sunday, 25 March 2018. Transfer into University of Cambridge. Wednesday, 21 June 2017. Who are we and what do we research? Introduction from the Director. Research at the MRC Mitochondrial Biology Unit. List of Unit publications. Mitochondria: Power houses, factories, waste disposal and recycling centres, and assassins. Genetic modification of the mitochondrial genome. The mitochondrial proteome (IMPI). On Sunday, 25 March ...

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mitominer.mrc-mbu.cam.ac.uk mitominer.mrc-mbu.cam.ac.uk

MitoMiner 4.0: Home

A database of mammalian mitochondrial localisation evidence, phenotypes and diseases. New to version 4.0? An integrated web resource of mitochondrial localisation evidence and phenotype data for mammals, zebrafish and yeasts. MitoMiner is now gene centric. With all data attached to gene objects. For best results search for a gene identifier such as an Ensembl id, gene symbol or genome project id (HGNC, MGI, RGD, SGD, ZFIN). If you are short of time, just navigate through our set of Feature Hints. Gene id...

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Medical Research Council: Mitochondrial Biology Unit

Sir John Walker Lecture. The primary electron acceptor flavin mononucleotide (FMN) in the hydrophilic domain of complex I from Thermus thermophilus. Crystals of the globular arm of complex I from Thermus thermophilus. The substrate binding site of the phosphate carrier from Saccharomyces cerevisiae. Electron paramagnetic resonance of complex I. The ring of c-subunits from bovine mitochondrial ATP synthase. Structure of the mitochondrial F-ATP synthase complex. Mitochondria in the fission state.

INTERNAL PAGES

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1

Mike Murphy | MRC Mitochondrial Biology Unit

http://www.mrc-mbu.cam.ac.uk/people/mike-murphy

Skip to main content. Targeting therapeutic and probe molecules to mitochondria, mitochondrial radical production and redox signalling. Menger KE, James AM, Cochemé HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L and Murphy MP. 2015) Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. 2014) Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Free Radic Biol Med. 2011) Measurement of...

2

Our Patron | MRC Mitochondrial Biology Unit

http://www.mrc-mbu.cam.ac.uk/our-patron

Skip to main content. Her Royal Highness The Princess Royal. Her Royal Highness The Princess Royal has agreed to extend her Patronage of the MRC Mitochondrial Biology Unit for a further three years, to December 2018. Seminar: Professor Gary Rudnick. Determinants of conformational change in an ion-coupled transporter. Seminar: Dr. Miratul Muqit. Decoding Parkinson's disease - the role of the PINK1 kinase. Seminar: Dr. Cole Haynes. Adaptations mediated by a mitochondrial UPR. Seminar: Professor Roland Lill.

3

Forthcoming Events | MRC Mitochondrial Biology Unit

http://www.mrc-mbu.cam.ac.uk/events

Skip to main content. Sep/06 15:00 - Sep/06 16:00. Sackler Lecture Theatre Wellcome Trust/MRC Building. Seminar: Professor Gary Rudnick. Tuesday, 6 September, 2016 - 15:00. Determinants of conformational change in an ion-coupled transporter. Read more about Seminar: Professor Gary Rudnick. Sep/07 15:00 - Sep/07 16:00. Sackler Lecture Theatre Wellcome Trust/MRC Building. Seminar: Dr. Miratul Muqit. Wednesday, 7 September, 2016 - 15:00. Decoding Parkinson's disease - the role of the PINK1 kinase. Seminar: ...

4

Ian Fearnley | MRC Mitochondrial Biology Unit

http://www.mrc-mbu.cam.ac.uk/people/ian-fearnley

Skip to main content. Identifying and characterising mitochondrial proteins and their associations. Mass spectrometry and proteomics have become important tools for studying biological systems. They provide the means to identify and characterise proteins within sub-cellular fractions or organelles, identify protein associations, and connect proteins with particular activities, functions or networks. Morales-Rios E, Watt IN, Zhang Q, Ding S, Fearnley IM, Montgomery MG, Wakelam MJO and Walker JE. 2014) A m...

5

Mike Murphy | MRC Mitochondrial Biology Unit

http://www.mrc-mbu.cam.ac.uk/people/murphy

Skip to main content. Targeting therapeutic and probe molecules to mitochondria, mitochondrial radical production and redox signalling. Menger KE, James AM, Cochemé HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L and Murphy MP. 2015) Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. 2014) Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS. Free Radic Biol Med. 2011) Measurement of...

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THE FOX GOT YOU - LINKS. Please come in and discover our world. The Fox Got You. Is an art and science project celebrating common plants at the origin of medicinal drugs (for an overview, go to the home page). On this page you will find links to the websites of the organisations featured in the project. 1: Mitochondrial Biology Unit. 2: Centre for Mechanochemical Cell Biology. 3: William Harvey Research Institute. FROM PLANTS TO DRUGS. HISTORY (click on images to show web links). 1: Ancient Yew Group.

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My Work | LettsScience

https://lettsscience.com/my-work

I am a Scientist. I recently started a postdoc as a MRC Career Development Fellow at the MRC Mitochondrial Biology Unit. In Cambridge, UK. Here I am working in the lab of Dr Leonid Sazanov. Studying the structure and function of the Nicotinamide Nucleotide Transhydrogenase (NNT), an important mitochondrial protein complex that sits at the interface of anabolism, catabolism and the proton motive force. In New York. My PhD adviser was Rod MacKinnon, so we normally just call it the MacKinnon Lab. Below is a...

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Communications, Media and Public Engagement in Cambridge. Adrian Penrose, Regional Communications Manager. Adrian is a member of the Chartered Institute of Public Relations (CIPR) and founding member of its Health and Medical Group. He is a member of the STEM (Science, Technology, Engineering and Maths) regional liaison group and is a member of the editorial board of the Journal of Healthcare Communications. Siblings' brain scans could hold the key to drug addiction. New study helps understanding of the ...

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The Research Office provides assistance with contractual issues to all MRC Units and laboratories in the Cambridge region in respect of collaborations, external funding applications, miscellaneous contracts, and the protection and exploitation of intellectual property. MRC Laboratory of Molecular Biology. Techtran@mrc-centre.cam.ac.uk. The Medical Research Council has entrusted the protection and exploitation of intellectual property developed in its laboratories to MRC Technology. Tel: 44 (0) 1223 268101.

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Our People - MRC Technology

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Who we work for. Who we work for. News / About Us / Contact Us. News / About Us / Contact Us. Dave Tapolczay Chief Executive. Dave is MRC Technology’s CEO. He has 28 years experience in R&D management and has been involved in the start-up of five companies, all of which are still trading. Edward Bliss General Counsel &. General Counsel and Company Secretary. Edward also manages our Licensing team. Justin Bryans Director, Drug. Michael Dalrymple Director, Business. Mike Johnson Director, Corporate. Paulin...

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Keynotes lectures | ECM Croatia

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The 29th European Crystallographic Meeting. August 23-28, 2015. Rovinj and Istria in photos. PDB & EMDB. DIALS by Diamond LS. ICDD Powder Diffraction Workshop. Young Crystallographers’ Meeting. Courier terms & conditions. ECM29 is held under the patronage of the Ministry of Science, Education and Sports of the Republic of Croatia. Call for Papers and Registration opening. Refund deadline for accommodation. Refund deadline for other all services. Presenting authors' registration deadline. AECC, Hall 5.

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MRC Centre - Freedom of Information (FoI) Act

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Freedom of Information (FoI) Act. Under the Freedom of Information Act 2000, all public authorities designated under the Act are obliged to adopt and maintain a publication scheme. The aim of the publication scheme is to set out:. The classes of information they publish or intend to publish as a matter of course. How the information is, or is intended to be, published. Whether the material is, or is intended to be, made available to the public free of charge or on payment. FOI Liaison Officer,. 2013, MRC...

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This site uses cookies. Read our policy. Subscribe to our newsletter. YSF Venue and Travel. Invited Speakers and Symposia Session Chairs. Marc A. Marti-Renom. Anne Bertolotti, UK. Marisol Soengas, Spain. Anne Willis, UK. Anne-Clause Gingras, Canada. Michael Kiebler, Germany. Nils Bluthgen, Germany. David I. Stuart. Ozlem Keskin, Turkey. Patrick Cramer, Germany. Pedro R. Cutillas. Richard Marais, UK. Gerhard Hummer, Germany. Himanshu Kumar, Netherlands. Ida van der Klei. Ilan Davis, UK. Jan Löwe, UK.

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MRC Mitochondrial Biology Unit | the involvement of mitochondria and their dysfunction in an ever-increasing range of human diseases

Skip to main content. Annual Sir John Walker Lecture. Thursday, 22 February 2018. Sunday, 25 March 2018. Transfer into University of Cambridge. Wednesday, 21 June 2017. Who are we and what do we research? Introduction from the Director. Research at the MRC Mitochondrial Biology Unit. List of Unit publications. Mitochondria: Power houses, factories, waste disposal and recycling centres, and assassins. Genetic modification of the mitochondrial genome. The mitochondrial proteome (IMPI). On Sunday, 25 March ...

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