Programs for electrophysiology. Includes diffusion, membrane potentials, sodium and potassium channels, equivalent circuit of the axon, nerve voltage clamp, membrane and propagated action potentials
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Simulations of ion channels and excitable membranes | nerve.bsd.uchicago.edu Reviews
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Programs for electrophysiology. Includes diffusion, membrane potentials, sodium and potassium channels, equivalent circuit of the axon, nerve voltage clamp, membrane and propagated action potentials
nerve.bsd.uchicago.edu
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http://nerve.bsd.uchicago.edu/KHTML/K_chan.htm
Voltage dependent Potassium Channel.
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http://nerve.bsd.uchicago.edu/CablePrep3.html
Study of the Passive Properties of the Axon. Many squids have giant axons. That result from the fusion of a number of small axons. The giant axon runs along the dorsal side of the mantle of the squid. The axon may be separated from the stellate ganglion and dissected out of the squid . The giant axon may cleaned from other nerve fibers and laid down on a recording chamber. To study the cable properties. Impaled through the membrane with respect to an external. Located far away from the injection point.
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http://nerve.bsd.uchicago.edu/med98a.htm
C) F Bezanilla, 1998. CAPACITANCE AND RESISTANCE OF THE MEMBRANE. ELECTRICAL MODEL OF THE MEMBRANE. THE RESTING MEMBRANE CONDUCTANCE. EQUIVALENT CIRCUIT OF THE MEMBRANE. POTASSIUM CURRENT AND POTASSIUM CONDUCTANCE. GENERATION OF THE ACTION POTENTIAL. PROPAGATION OF THE ACTION POTENTIAL. This membrane. This potential difference, or. The Capacitance and Resistance of the membrane. Where the two conducting plates are the ionic media and the membrane is the dielectric. The capacitance. Is the membrane area,.
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CIRCUIT OF THE AXON MEMBRANE. This program shows the equivalent circuit of the membrane capacitance and the three main conductances of the squid giant axon. The conductances are shown as. The reversal potentials as batteries and the currents as the degree of darkness in the conductors. In this mode, the conductance values are fixed to the values last used in the Interactive circuit mode and the time course of the currents and membrane voltage are shown in the main screen and in the plot window.
Home Page for Francisco Bezanilla, Ph.D.
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Francisco Bezanilla, Ph.D. Lillian Eichelberger Cannon Professor. Department of Biochemistry and Molecular Biology. The University of Chicago. GCIS Building room W244. 929 E 57th Street. Chicago, IL 60637. Emeritus Professor, Dept. of Physiology, UCLA. Member Centro Interdisciplinario de Neurociencias Univ. de Valparaiso, Chile. Biophysics of excitation: Structure-Function in Voltage Dependent Ionic Channels and Transport proteins. Of Dr Francisco Bezanilla. Members in the Correa-Bezanilla Laboratory:.
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Simulations of ion channels and excitable membranes
And The Molecular Basis of Excitability. This is a brief Textbook that covers the basics of the initiation and propagation of the nerve impulse using equivalent circuits with reference to ionic conductances. Voltage dependent conductances are explained on the basis of single channel properties. The text contains links to the simulation programs. If you get an error, right click on. DOWNLOAD pdf FILE] and click on '. Save target as '. Nerve Impulse Laboratory Manual. Experiments using the NERVE program.
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