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Novel Targets Podcast Bringing Science to Life

Novel Targets Podcast brings to life science of innovative new drugs, cell and gene therapies in development

http://www.noveltargets.com/

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Novel Targets Podcast Bringing Science to Life | noveltargets.com Reviews
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Novel Targets Podcast brings to life science of innovative new drugs, cell and gene therapies in development
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Novel Targets Podcast Bringing Science to Life | noveltargets.com Reviews

https://noveltargets.com

Novel Targets Podcast brings to life science of innovative new drugs, cell and gene therapies in development

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About Novel Targets Podcast | Novel Targets Podcast

http://noveltargets.com/about

This is a placeholder for your sticky navigation bar. It should not be visible. Novel Targets is a podcast about the science and people involved in the development of innovative new drugs, gene and cell therapies. The show looks at some of the exciting and emerging new approaches that could make a difference to the lives of patients. It discusses data from clinical trials and engages experts. The aim is to inform, educate and create awareness. It occasionally entertains. Sally Church, PhD. Helping people...

2

Lung Cancer Immunotherapy Roy Herbst Interview | Novel Targets Podcast

http://noveltargets.com/2015/04/lung-cancer-immunotherapy

This is a placeholder for your sticky navigation bar. It should not be visible. April 8, 2015. Prologue 3: Lung Cancer Immunotherapy. Lung cancer is the leading cause of cancer death in the United States. 8220; Personalized Immunotherapy for Non-Small Cell Lung Cancer. Was the title of an outstanding presentation by Roy Herbst MD PhD, at last year’s annual meeting of the Society for Immunotherapy of Cancer ( SITC. Other checkpoint inhibitors in clinical trials for advanced lung cancer include: pembrolizu...

3

Using Our Immune System to Fight Cancer | Novel Targets Podcast

http://noveltargets.com/2015/04/using-our-immune-system-to-fight-cancer

This is a placeholder for your sticky navigation bar. It should not be visible. April 3, 2015. Prologue 2: Using our Immune System to Fight Cancer. Daniel Chen MD PhD, Photo Courtesy of Genentech. Cancer Immunotherapy is one of the topics we will be talking about a lot on the podcast. As we gear up to the first episode, we thought we would share a few stories that set the scene, what we are calling a prologue. The interview was broadcast in the December 7, 2014 edition of the Sound Medicine Radio Hour.

4

CAR T Cell Cancer Immunotherapy | Novel Targets Podcast

http://noveltargets.com/2015/04/promise-of-car-t-cell-cancer-immunotherapy

This is a placeholder for your sticky navigation bar. It should not be visible. April 2, 2015. Prologue 1: Promise of CAR T Cell Cancer Immunotherapy. One of the hottest topics in Cancer Research is using the body’s immune system to fight cancer. This report discusses the promise of Chimeric Antigen Receptor (CAR) T Cell Therapy. It was previously broadcast on the Sound Medicine Radio Hour. On March 22, 2015. Dr Stephan Grupp presents data at ASH 2014 media briefing moderated by Dr Catherine Bollard.

5

Episode 4: Non-Inflamed Tumor Show | Novel Targets Podcast

http://noveltargets.com/2015/07/episode-4-non-inflamed-tumor-show

This is a placeholder for your sticky navigation bar. It should not be visible. July 21, 2015. Episode 4: Non-Inflamed Tumor Show. Checkpoint inhibitors do not work well in cancers where there is no underlying immune response. One example of such a non-inflamed tumor is prostate cancer. So a key question is how do we convert a non-inflamed tumor (where few T Cells present) into an inflamed one (T cells are plentiful and active)? In this latest episode, using prostate cancer as an example, Dr James Gulley.

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Can Merck make an impact in pancreatic cancer? | Pharma Strategy Blog

http://pharmastrategyblog.com/2013/10/can-merck-make-an-impact-in-pancreatic-cancer.html

Commentary on Pharma and Biotech Oncology / Hematology New Product Development. Can Merck make an impact in pancreatic cancer? There were a number of interesting posters at the AACR-NCI-EORTC Molecular Targets meeting today. Specifically, two on metastatic pancreatic cancer caught my eye. You can read about the other one on Millennium/Takeda’s ADC MLN0264 here. Many of you will be aware that KRAS is mutated in 90% of pancreatic cancer cases. As Dr Barry Nelkin (Johns Hopkins) noted today,. Dinaciclib (Me...

pharmastrategyblog.com pharmastrategyblog.com

Is there a biomarker for germ-line BRCA mutated cancers? | Pharma Strategy Blog

http://pharmastrategyblog.com/2014/02/developing-a-predictive-biomarker-for-parp-inhibition.html

Commentary on Pharma and Biotech Oncology / Hematology New Product Development. Developing a predictive biomarker for PARP inhibition. Post looks at the identification of a potential new biomarker and possible strategies for expanding use of PARP inhibitors in patients most likely to respond to them as a way to validate the the approach prospectively. This has important implications for future clinical trial designs with this class of drugs. Photo Credit: Ben Sutherland via flickr. PARP1/2 inhibitors hav...

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Idelalisib and PI3K-delta in NHL and CLL | Pharma Strategy Blog

http://pharmastrategyblog.com/2014/01/making-a-difference-in-nhl-and-cll-an-interview-with-dr-carol-gallagher.html

Commentary on Pharma and Biotech Oncology / Hematology New Product Development. Making a difference in NHL and CLL: an interview with Dr Carol Gallagher. For as long as anyone can remember, humanity has wondered, “Why do we do things even when we know we should not? James Shelley, Caesura Letters. Or even specific, well defined subsets to improve the homogeneity ratio? Or perhaps they knowingly underpower a randomized trial for overall survival? The list goes on…. A head-desk kind of moment to be sure.

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Remembering WW1 | Pieter Droppert

http://pieterdroppert.com/remembering-ww1

A digital media journey – it's all about the story. One of the most poignant reminders of the sacrifices of World War 1 is the field of 888,246 ceramic poppies being installed in the moat of the Tower of London. Designed by artist Paul Cummins, each poppy signifies one of the British or Colonial deaths in WW1. The hand-made poppies are part of an artwork entitled “Blood swept lands and seas of red”. 8220;we celebrate the lives of those who gave their lives so we can enjoy the freedoms we have today”.

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Albert Dock Evening Walk | Pieter Droppert

http://pieterdroppert.com/albert-dock-evening-walk

A digital media journey – it's all about the story. Wheel of Liverpool & Echo Arena. View towards Pier Head. Albert Dock Tate Gallery. Mersey Ferry at Pier Head. Albert Dock Evening Walk. A walk around the Albert Dock to the Liverpool Pier Head in the glorious blue hour after sunset on March 4, 2014. Camera: Panasonic LX7.

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St Charles Streetcar New Orleans | Pieter Droppert

http://pieterdroppert.com/st-charles-streetcar-new-orleans

A digital media journey – it's all about the story. St Charles Streetcar New Orleans. The St. Charles streetcar line in New Orleans started in 1835 and is the oldest continually operating streetcar service in the world. The bottle green arch-roofed, steel bodied Perley-Thomas streetcars used today, have been in operation since 1923-24. The St. Charles line was listed by the National Park Service as a Historic Landmark in 2014.

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Combination immunotherapy strategies in advanced prostate cancer | Icarus Consultants

http://icarusconsultants.com/are-checkpoint-inhibitors-effective-in-prostate-cancer

Pharma New Products Strategy and Market Analysis with a focus on oncology and hematology. Icarus Custom Menu Bar. Are Checkpoint Inhibitors effective in Prostate Cancer? March 2, 2015. Many readers will be aware that the ASCO Genitourinary Symposium (ASCO GU) Symposium in Orlando took place this past weekend. So where does the field go from here, and will prostate cancer benefit from the cancer immunotherapy revolution? Tumour progression is associated with the evasion of immunosurveillance,. The cytotox...

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2015 is Year of Gene Editing | Icarus Consultants

http://icarusconsultants.com/2015-is-the-year-of-gene-editing

Pharma New Products Strategy and Market Analysis with a focus on oncology and hematology. Icarus Custom Menu Bar. 2015 is the year of Gene Editing. January 7, 2015. Last year we (and many others) declared 2014 to be the year of immuno-oncology, and while this will continue to remain a hot area for drug development, we predict 2015 will be the year of gene editing. Paris based Cellectis (ALCLS), a company we have been following for some time, announced yesterday ( link to Cellectis press release. That the...

pharmastrategyblog.com pharmastrategyblog.com

Uncoupling the PD-1 brake enhances CART in a solid tumor model | Pharma Strategy Blog

http://pharmastrategyblog.com/2013/10/removing-the-pd-1-brake-enhances-the-effect-on-adoptive-car-t-cells.html

Commentary on Pharma and Biotech Oncology / Hematology New Product Development. Removing the PD-1 brake enhances the effect on adoptive CAR T cells. Someone in my Twitter stream kindly shared a link to an article this morning on how removing the PD-1 brake enhances the effect of chimeric antigen receptor (CAR) T cells in solid tumour models. Read that again and digest the implications. Certainly it gave me goosebumps reading the articles. What do the papers show? Ovarian and breast cancers have been ment...

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Dr Sally Church Oncology Hematology | Pharma Strategy Blog

http://pharmastrategyblog.com/about

Commentary on Pharma and Biotech Oncology / Hematology New Product Development. This blog is written by Sally Church, Ph.D. I am an English scientist (a biochemist), interested in the biology of cancer and write this blog in my spare time when not playing fantasy football. My particular interests include oncology, hematology, respiratory and immunology. My academic qualifications include a Masters degree in Human and Applied Physiology and a Doctorate. I’ve not been updating the blog since 2014, so...

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Novel Targets Podcast Bringing Science to Life

SIGN UP for Newsletter. Bringing to life the science around innovative new drugs, gene and cell therapies. July 21, 2015. Episode 4: Non-Inflamed Tumor Show. Checkpoint inhibitors do not work well in cancers where there is no underlying immune response. One example of such a non-inflamed tumor is prostate cancer. So a key question is how do we convert a non-inflamed tumor (where few T Cells present) into an inflamed one (T cells are plentiful and active)? June 12, 2015. Episode 3: ASCO Lung Cancer Show.

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