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Northwest Regional Center of Excellence

Genotype-phenotype associations in a nonmodel prokaryote. Measuring growth of tranpsoson mutants under a variety of nutrition and stress conditions helped define the biological functions of nonessential genes of Francisella novicida. Coordinated host responses during pyroptosis. Two conserved secretion pathways are shown to be initiated by caspase-1, lysosome exocytosis, and a parallel pathway resulting in cytokine release, and both enhance the antimicrobial nature of pyroptosis. April 7-9, 2013. E P (Pe...

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CONTACTS AT NWRCE.ORG

John Kemner

1959 NE Pa●●●●●●●●●●Box 357710

Se●●le , WA, 98195

US

1.20●●●●5708
jm●●●●●●@u.washington.edu

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John Kemner

1959 NE Pa●●●●●●●●●●Box 357710

Se●●le , WA, 98195

US

1.20●●●●5708
jm●●●●●●@u.washington.edu

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Matthew Radey

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Se●●le , WA, 98195

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Northwest Regional Center of Excellence | nwrce.org Reviews
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Genotype-phenotype associations in a nonmodel prokaryote. Measuring growth of tranpsoson mutants under a variety of nutrition and stress conditions helped define the biological functions of nonessential genes of Francisella novicida. Coordinated host responses during pyroptosis. Two conserved secretion pathways are shown to be initiated by caspase-1, lysosome exocytosis, and a parallel pathway resulting in cytokine release, and both enhance the antimicrobial nature of pyroptosis. April 7-9, 2013. E P (Pe...
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2 opportunities
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5 participating institutions
6 directors
7 external advisory board
8 affiliated rces
9 research
10 research projects
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Northwest Regional Center of Excellence | nwrce.org Reviews

https://nwrce.org

Genotype-phenotype associations in a nonmodel prokaryote. Measuring growth of tranpsoson mutants under a variety of nutrition and stress conditions helped define the biological functions of nonessential genes of Francisella novicida. Coordinated host responses during pyroptosis. Two conserved secretion pathways are shown to be initiated by caspase-1, lysosome exocytosis, and a parallel pathway resulting in cytokine release, and both enhance the antimicrobial nature of pyroptosis. April 7-9, 2013. E P (Pe...

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nwrce.org nwrce.org
1

Northwest Regional Center of Excellence

http://www.nwrce.org/about-us/directors

Samuel I Miller, M.D. Brad Cookson, M.D., Ph.D. Associate Director and Development Director. Jeffrey S. Duchin, M.D. Director of Emergency Response. John Kemner, Ph.D. NIAID Bioinformatics Resource Centers. Emergency Preparedness and Response Information. Copy 2012, Northwest Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research Privacy.

2

Northwest Regional Center of Excellence

http://www.nwrce.org/about-us/overview

The Northwest Regional Center of Excellence (NWRCE) is one of eleven regional Regional Centers of Excellence for Biodefense and Emerging Infectious Diseases Research. These centers have been established by the National Institute of Allergy and Infectious Diseases (NIAID) , a component of the National Institutes of Health (NIH) of the Department of Health and Human Services. NIAID supports basic and applied research to prevent, diagnose and treat infectious and immune-mediated illnesses.

3

Northwest Regional Center of Excellence

http://www.nwrce.org/about-us/participating-institutions

The following institutions participate in NWRCE activities and perform a wide range of valuable research for the NWRCE. Please visit the websites for more information about these institutions. Fred Hutchinson Cancer Research Center. Institute for Systems Biology. NAIAD Rocky Mountain Laboratories. Oregon Health and Sciences University. University of Alaska Fairbanks. VA Puget Sound Health Care System. NIAID Bioinformatics Resource Centers. Emergency Preparedness and Response Information.

4

Northwest Regional Center of Excellence

http://www.nwrce.org/resources/mass-spectrometry-core

Dr David R. Goodlett. Department of Medicinal Chemistry. University of Washington, Seattle, WA. Specifically, the core determines structures of proteins and protein complexes, determines structures of small molecules and screen libraries, and characterizes Global Protein Regulation. To carry out these aims the core utilizes a number of technologies including, but not limited to, the following:. High Performance Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry.

5

Northwest Regional Center of Excellence

http://www.nwrce.org/rce-events

We will be hosting a training workshop for our PGAT tool on Tuesday Sept. 24th from 2-4pm in HSB K350. Researchers are invited to bring their own work with them and the developers of PGAT will be available to answer questions and demonstrate features of the tool. 2013 National Meeting of the RCE Network. The NWRCE will be hosting the 2013 National Meeting of the RCE network on April 7-9, 2013. The Westin Hotel Seattle. Seattle, WA 98101. RCE National Meeting Program. RCE National Meeting Details.

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Our Customers

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Rotating Drum Static Aerosol Chamber. Agency for Defense Development, Daejeon, Republic of Korea. Http:/ www.add.re.kr/. Armed Forces Institute of Pathology, Washington, DC. Boston University, Boston, MA. National Emerging Infectious Disease Laboratory. Centers for Disease Control and Prevention, Atlanta, GA. National Center for Immunization and Respiratory Diseases. Duke University, Durham, NC. Wwwhumanvaccine.duke.edu/modules/Shared Resources/index.php? University of Florida, Orlando, FL. Http:/ www&#4...

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Francisella tularensis Genome Research

http://www.francisella.org/links.htm

Resource Center for Biodefense Proteomics Research. Y2H interaction data on F. tularensis. Generated by the Proteomics Research Center (PRC) in Salt Lake City (Myriad Genetics) is publicly available through this website. The website provides various datasets on 14 additional category A-C and emerging pathogens. Northwest RCE (Regional Center of Excellence). The Northwest Regional Center of Excellence (NWRCE) develops several of the web tools available on francisella.org for F. tularensis.

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Genotype-phenotype associations in a nonmodel prokaryote. Measuring growth of tranpsoson mutants under a variety of nutrition and stress conditions helped define the biological functions of nonessential genes of Francisella novicida. Coordinated host responses during pyroptosis. Two conserved secretion pathways are shown to be initiated by caspase-1, lysosome exocytosis, and a parallel pathway resulting in cytokine release, and both enhance the antimicrobial nature of pyroptosis. April 7-9, 2013. E P (Pe...

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