NEWS WHO WE ARE Founded by nine eminent research institutions in 1999, NYSBC is a global leader in structural biology with unsurpassed expertise and instrumentation, providing biomedical research services to commercial and academic clients, including high throughput gene-to -structure determination, structure-based drug design, crystallography, NMR spectroscopy, cryo-electron microscopy
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New York Structural Biology Center
New York Structural Biology Center
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NYSBC | nysbc.org Reviews
https://nysbc.org
NEWS WHO WE ARE Founded by nine eminent research institutions in 1999, NYSBC is a global leader in structural biology with unsurpassed expertise and instrumentation, providing biomedical research services to commercial and academic clients, including high throughput gene-to -structure determination, structure-based drug design, crystallography, NMR spectroscopy, cryo-electron microscopy
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EMGWEB.NYSBC.ORG Appion and Leginon Tools. Login as "Anonymous" for viewing public data sets (Does not required a username and password).
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NRAMM Appion and Leginon Tools. NYSBC users use http:/ emgweb.nysbc.org. To access EMG Appion and Leginon Tools. Login as "Anonymous" for viewing public data sets (Does not required a username and password).
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The National Resource for Automated Molecular Microscopy (NRAMM) is a Biomedical Technology Research Center. Based at New York Structural Biology Center. Our mission is to develop, test and apply technology aimed towards completely automating the processes involved in solving macromolecular structure using cryo-electron microscopy (cryoEM). Our goal is to both serve as a center for high-throughput molecular imaging and to transfer this technology to the research community. August 14, 2015. August 25, 2014.
PSI Center for Electron Crystallography
The Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS) is a research consortium funded by the NIH Protein Structure Initiative:Biology program. At TEMIMPS, we are dedicated to structure determination of a variety of eukaryotic membrane protein targets. In particular, we are developing a pipeline that includes two-dimensional crystallization of membrane proteins, electron cryo-microscopy and image analysis to achieve this goal. Five different laboratories from across the Unite...
nysbc.org
NYSBC - New York Structural Biology Center
http://nysbc.org/education-events/training-courses
Simons Electron Microscopy Center. Major Grants & Contracts. X-Ray Department: All Publications (2014-2015). NMR Department: All Publications (2014-2015). SEMC: All Publications (2014-2015). Membrane Proteins (COMPPÅ): All Publications (2014-2015). Special Projects Group: All Publications (2014-2015). NYSBC offers three semester long, fully accredited, graduate level courses available to students from NYSBC’s 9 member institutions:. NMR Spectroscopy of Macromolecules. Have only a limited exposure to mult...
NYSBC - New York Structural Biology Center
http://nysbc.org/major-grants-contracts/nycomps
Simons Electron Microscopy Center. Major Grants & Contracts. X-Ray Department: All Publications (2014-2015). NMR Department: All Publications (2014-2015). SEMC: All Publications (2014-2015). Membrane Proteins (COMPPÅ): All Publications (2014-2015). Special Projects Group: All Publications (2014-2015). Major Grants and Contracts. The COMPPÅ has automation and high throughput capabilities for accelerating membrane protein research. Beckman Coulter Biomek FX Liquid Handling Robot. 89 Convent Ave, New York, ...
NYSBC - New York Structural Biology Center
http://nysbc.org/staff/administration
Simons Electron Microscopy Center. Major Grants & Contracts. X-Ray Department: All Publications (2014-2015). NMR Department: All Publications (2014-2015). SEMC: All Publications (2014-2015). Membrane Proteins (COMPPÅ): All Publications (2014-2015). Special Projects Group: All Publications (2014-2015). Willa Appel, Ph.D. Senior Grants and Contracts Manager. 89 Convent Ave, New York, NY 10027 (212) 939-0660.
NYSBC - New York Structural Biology Center
http://nysbc.org/staff/scientific-staff
Simons Electron Microscopy Center. Major Grants & Contracts. X-Ray Department: All Publications (2014-2015). NMR Department: All Publications (2014-2015). SEMC: All Publications (2014-2015). Membrane Proteins (COMPPÅ): All Publications (2014-2015). Special Projects Group: All Publications (2014-2015). Willa Appel, Ph.D. Wayne Hendrickson, Ph.D. University Professor, Biochemistry and Molecular Biophysics, Columbia University). Arthur Palmer, III, Ph.D. Bridget Carragher, Ph.D. Wayne Hendrickson, Ph.D.
NYSBC - New York Structural Biology Center
http://nysbc.org/major-grants-contracts
Simons Electron Microscopy Center. Major Grants & Contracts. X-Ray Department: All Publications (2014-2015). NMR Department: All Publications (2014-2015). SEMC: All Publications (2014-2015). Membrane Proteins (COMPPÅ): All Publications (2014-2015). Special Projects Group: All Publications (2014-2015). Major Grants & Contracts. Major Grants and Contracts. In addition to our three research departments, the Center has several initiatives funded by grants and/or contracts. Read more here:.
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Wayne Hendrickson Laboratory
http://convex.hhmi.columbia.edu/2010/links.html
Wayne A. Hendrickson, Columbia University.
Customer Sites
http://www.extendresearch.com/customersites.html
EXtend Research, LLC. Extending Market & Financial Research - providing a unique & detailed perspective on the MRI, NMR and Molecular Imaging Markets. Customer Sites & Important Research Links. Http:/ www.humanconnectomeproject.org/. University of Minnesota, Center for Magnetic Resonance Research. Https:/ www.cmrr.umn.edu/. Dr Gregor Adriany overseing delivery of the world's first 10.5T human MRI magnet. U Minn. CRMM. Http:/ www.chem.wisc.edu/users/cavagner. Http:/ www.bio-nmr.net/.
Synaptic
https://www.synaptic.bio/services/5
New York Structural Biology Center. We provide cloning, expression, purification and refolding of proteins in bacterial, insect and mammalian cell lines. Large scale, high throughput projects are performed using our automated cloning stations and protein chromatography systems. For X-ray crystallography projects, five automated crystallization screening/imaging systems are available. We have expertise with membrane proteins, a challenging but therapeutically important category.
NRAMM Releases Leginon and Appion version 3.1
http://nramm.nysbc.org/nramm-releases-leginon-and-appion-version-3-1
NRAMM Releases Leginon and Appion version 3.1. August 25, 2014. 31 is released mainly to mark the support for FEI Falcon Camera, both for data acquisition in Leginon and frame processing in Appion. Minor features affecting the user and installation experiences are also added. More information regarding new features are available here. And the general change log for Appion/Leginon 3.1.0. And http:/ appion.org. Contact us at nrammsoft@nysbc.org. 1] http:/ leginon.org. 2] http:/ appion.org.
Resources for the Dept. of Physiology and Biophysics, Weill Cornell Medical College
http://physiology.med.cornell.edu/resources
Department of Physiology and Biophysics. Institute for Computational Biomedicine. Tri-I Bioinformatics and Computational Workshops. Computational Biology Service Unit. Other Resources in New York City. New York Academy of Sciences. New York Structural Biology Center.
Acknowledgment
http://nramm.nysbc.org/acknowledgment
The National Resource for Automated Molecular Microscopy is supported by a grant from the National Institute of General Medical Sciences (9 P41 GM103310) from the National Institutes of Health. 2016 National Resource for Automated Molecular Microscopy. Powered by Pinboard Theme.
Using NRAMM
http://nramm.nysbc.org/using-nramm-2
The mission at NRAMM is to develop cryoEM as a mainstream and efficient methodology on a par with, and complementary to, X-ray crystallography and other equivalent hybrid structural methods. In addition, we see a role for structural EM as being uniquely capable of providing information about the dynamics of molecular machines. Technology Research and Development. TRD) efforts in the current funding cycle are focused in 3 areas: TRD#1: CryoEM Specimen Preparation Using Piezo-based Picoliter Dispensing.
Publications
http://nramm.nysbc.org/publications
Ballandras-Colas A, Brown M, Cook NJ, Dewdney TG, Demeler B, Cherepanov P, Lyumkis D, Engelman AN. Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature. 2016;530(7590):358-61. PMCID: 4908968. Pubmed. Gui L, Ebner JL, Mileant A, Williams JA, Lee KK. Visualization and sequencing of membrane remodeling leading to influenza virus fusion. J Virol. 2016. PMCID: In Process. Pubmed. Short JR, Speir JA, Gopal R, Pankratz LM, Lanman J, Schneemann A. Atomic structure of...
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How To Work With Us. Simons Electron Microscopy Center. PUBLICATIONS & POLICIES. Acknowledgment and Authorship at NYSBC. Membrane Proteins (COMPPÅ) Publications. Directions to NYC Offices. Directions to Brookhaven National Lab. How To Work With Us. Simons Electron Microscopy Center. PUBLICATIONS & POLICIES. Acknowledgment and Authorship at NYSBC. Membrane Proteins (COMPPÅ) Publications. Directions to NYC Offices. Directions to Brookhaven National Lab. For full press release click here. 10,000-fold bright...
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