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GPCR-ModSim

A pipeline for computational modeling and simulation of G-Protein Coupled Receptors (GPCRs). To model a GPCR look for the navigation bar at the top of the page and click on Model a GPCR. This will take you to a new window where you can choose to either input a GPCR sequence or use a known Uniprot ID for homology modeling. You will also be able to click on the box "Upload your GPCR PDB file" to upload a PDB file which will be embeded in a phospholipid bilayer and modeled using Molecular Dynamics.

http://open.gpcr-modsim.org/

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GPCR-ModSim | open.gpcr-modsim.org Reviews
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A pipeline for computational modeling and simulation of G-Protein Coupled Receptors (GPCRs). To model a GPCR look for the navigation bar at the top of the page and click on Model a GPCR. This will take you to a new window where you can choose to either input a GPCR sequence or use a known Uniprot ID for homology modeling. You will also be able to click on the box Upload your GPCR PDB file to upload a PDB file which will be embeded in a phospholipid bilayer and modeled using Molecular Dynamics.
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2 projects
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5 welcome to gpcr modsim
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GPCR-ModSim | open.gpcr-modsim.org Reviews

https://open.gpcr-modsim.org

A pipeline for computational modeling and simulation of G-Protein Coupled Receptors (GPCRs). To model a GPCR look for the navigation bar at the top of the page and click on Model a GPCR. This will take you to a new window where you can choose to either input a GPCR sequence or use a known Uniprot ID for homology modeling. You will also be able to click on the box "Upload your GPCR PDB file" to upload a PDB file which will be embeded in a phospholipid bilayer and modeled using Molecular Dynamics.

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open.gpcr-modsim.org open.gpcr-modsim.org
1

GPCR-ModSim

http://open.gpcr-modsim.org/tutorials

Human Orexin Receptor Type 2. Adenosine A2A Receptor with Caffeine. Our you-tube channel with tutorials and movies. On GPCR modeling at GPCR-ModSim.

2

GPCR-ModSim

http://open.gpcr-modsim.org/projects

Click here to Register.

3

GPCR-ModSim

http://open.gpcr-modsim.org/publications

The following is a selection of the papers about GPCRs published by the GPCR modeling team. Esguerra M., Siretskiy A., Bello X., Sallander J. and Gutiérrez-de-Terán H. GPCR-ModSim: A comprehensive web based solution for modeling G-protein coupled receptors. NAR, W455-W462, (2016), DOI: 10.1093/nar/gkw403 Link: pubmed. Abel Crespo, Abdelaziz El Maatougui, Pierfrancesco Biagini, Jhonny Azuaje, Alberto Coelho, José Brea, María Isabel Loza, María Isabel Cadavid, Xerardo García-Mera, Hugo Gutiérrez-de-Terán.

4

GPCR-ModSim

http://open.gpcr-modsim.org/about

This server was created to allow any researcher with interest in GPCRs to obtain the most accurate structural and dynamic information for a given receptor. Here, you can generate a homology-based 3D model of your query GPCR sequence, and/or further equilibrate your GPCR structure with our all-atom Molecular Dynamics simulation protocol. If this is your first time here, please register. As a new user, and allow a brief tour through our tutorial. Afterwards you can log in. And about the GPCR-ModSim project.

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GPCR-ModSim

A pipeline for computational modeling and simulation of G-Protein Coupled Receptors (GPCRs). To model a GPCR look for the navigation bar at the top of the page and click on Model a GPCR. This will take you to a new window where you can choose to either input a GPCR sequence or use a known Uniprot ID for homology modeling. You will also be able to click on the box "Upload your GPCR PDB file" to upload a PDB file which will be embeded in a phospholipid bilayer and modeled using Molecular Dynamics.

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