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Introduction of biosimilars: not to be confused with generics | Prescriber Forum

https://prescriberjournal.wordpress.com/2013/09/23/introduction-of-biosimilars-not-to-be-confused-with-generics

Introduction of biosimilars: not to be confused with generics. MSc, MPhil, DIC, DUniv, FRPharmS. Generic versions of branded medicines have been with us for a long time there was a proliferation of generic versions of aspirin, for example, when Bayer’s patent expired in 1917. So when is a generic not a generic? A generic isn’t a generic when it’s a biological drug. Biological drugs (biologics) are, generally, large molecules based on sugars, proteins, nucleic acids or complex combinations of these su...

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prescriberjournal | Prescriber Forum

https://prescriberjournal.wordpress.com/author/prescriberjournal

Affording expensive new drugs. BMedSci, MRCGP, DRCOG, DipTher, DPH. Often lost in the indignant protests over the NHS not funding the latest ‘wonder drug’ is that such drugs can be eye-wateringly expensive. The latest furore has been over NICE’s provisional determination on Kadcyla (trastuzumab emtansine) the view from NICE was that this drug is not cost-effective unless the drug company reduces the price, which they have so far declined to do. The incremental cost-effectiveness ratio was estimated in th...

3

NICE CG178 on psychosis – an evidence-based guideline? | Prescriber Forum

https://prescriberjournal.wordpress.com/2014/04/24/nice-cg178-on-psychosis-an-evidence-based-guideline

NICE CG178 on psychosis an evidence-based guideline? MB BS and Mark Taylor. BSc, MD, FRCPsych, FRANZCP. In this editorial we summarise and critique NICE clinical guideline on. Psychosis and Schizophrenia in Adults: Treatment and Management. CBT as a panacea? And thus may not have capacity to consent to their treatment. Failure to offer the most evidence-based treatments promptly could be viewed as breaching the duty of care by the practitioner. It is also interesting that NICE seems to have ignored p...

4

Polypharmacy – essential, but also to be avoided | Prescriber Forum

https://prescriberjournal.wordpress.com/2014/02/06/polypharmacy-essential-but-also-to-be-avoided

Polypharmacy essential, but also to be avoided. BMedSci, MRCGP, DRCOG, DipTher, DPH. Polypharmacy is not new it was first described and discussed in the medical literature at least 150 years ago. Despite this, other than the dictionary definition of prescribing more than one drug at the same time to an individual, it is has been poorly characterised and under-researched. Problematic polypharmacy is defined as the prescribing of multiple medications inappropriately, or where the intended benefit of the me...

5

Affording expensive new drugs | Prescriber Forum

https://prescriberjournal.wordpress.com/2014/06/06/affording-expensive-new-drugs

Affording expensive new drugs. BMedSci, MRCGP, DRCOG, DipTher, DPH. Often lost in the indignant protests over the NHS not funding the latest ‘wonder drug’ is that such drugs can be eye-wateringly expensive. The latest furore has been over NICE’s provisional determination on Kadcyla (trastuzumab emtansine) the view from NICE was that this drug is not cost-effective unless the drug company reduces the price, which they have so far declined to do. The incremental cost-effectiveness ratio was estimated in th...

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Prescriber Forum | www.prescriber.co.uk

Affording expensive new drugs. BMedSci, MRCGP, DRCOG, DipTher, DPH. Often lost in the indignant protests over the NHS not funding the latest ‘wonder drug’ is that such drugs can be eye-wateringly expensive. The latest furore has been over NICE’s provisional determination on Kadcyla (trastuzumab emtansine) the view from NICE was that this drug is not cost-effective unless the drug company reduces the price, which they have so far declined to do. The incremental cost-effectiveness ratio was estimated in th...

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Prescriber's Letter: Unbiased Recommendations You Can Trust on New Developments in Drug Therapy

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