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Hereditary Cancer Risks & Multiplex Gene Panels | PROMPT

YOU CAN HELP RESEARCHERS BETTER UNDERSTAND WHO IS AT RISK FOR HEREDITARY CANCER Welcome to the Prospective Registry Of MultiPlex Testing (PROMPT). This online research registry for patients and their families helps researchers answer the question:

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Hereditary Cancer Risks & Multiplex Gene Panels | PROMPT | promptstudy.info Reviews
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YOU CAN HELP RESEARCHERS BETTER UNDERSTAND WHO IS AT RISK FOR HEREDITARY CANCER Welcome to the Prospective Registry Of MultiPlex Testing (PROMPT). This online research registry for patients and their families helps researchers answer the question:
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1 about prompt
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about prompt,founding institutions,info for providers,partners,general info,literature,take action,menu,what we do,genes,brca1 and brca2,enroll today,prompt@uphs upenn edu,or medprompt@mskcc org
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Hereditary Cancer Risks & Multiplex Gene Panels | PROMPT | promptstudy.info Reviews

https://promptstudy.info

YOU CAN HELP RESEARCHERS BETTER UNDERSTAND WHO IS AT RISK FOR HEREDITARY CANCER Welcome to the Prospective Registry Of MultiPlex Testing (PROMPT). This online research registry for patients and their families helps researchers answer the question:

INTERNAL PAGES

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1

PALB2 - PROMPT

http://promptstudy.info/geneinfo/palb2

PROMPT in the Press. PROMPT in the Press. Gene plays an important role in allowing the cell to repair itself and is a partner of BRCA2. Gene is classified as a moderate risk gene, meaning that there is a modestly increased risk for certain types of cancers. For example, women who have one. Pathogenic gene mutation likely have a relative risk of approximately 3 for breast cancer in comparison to the general population. Rarely, an individual will inherit two. Cancer screening and risk-reducing options.

2

Referring Patients for Multiplex Gene Panels | PROMPT

http://promptstudy.info/providerinfo

PROMPT in the Press. PROMPT in the Press. INFORMATION FOR HEALTHCARE PROVIDERS AND LIFE SCIENCE COMPANIES. If you’re a genetic counselor, researcher, or physician, you understand the valuable role multiplex testing can play in understanding the genesis of certain cancers. HERE IS ALL THE INFORMATION YOU NEED. Click on the tabs below to find out more about PROMPT. How To Recruit Participants. You can download and print the PROMPT Brochure in PDF format by clicking here. How does it work? How secure is it?

3

Literature - PROMPT

http://promptstudy.info/geneliterature

PROMPT in the Press. PROMPT in the Press. Please check back regularly for updates. Castéra L, Krieger S, Rousselin A, et al: Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate gene. Eur J Hum Genet Epub ahead of print, 2014. Domchek SM, Bradbury A, Garber JE, et al: Multiplex genetic testing for cancer susceptibility: out on the high wire without a net? J Clin Oncol 31(10):1267-70, 2013. Semin Oncol 39:26-36, 2012. Brune...

4

CHEK2 - PROMPT

http://promptstudy.info/geneinfo/chek2

PROMPT in the Press. PROMPT in the Press. Gene plays role in cell regulation. Certain changes (mutations) in the CHEK2 gene are associated with an increased risk of cancer. Gene is classified as a moderate risk gene, meaning that there is a modestly increased risk for certain types of cancers. For example, women who have one. Pathogenic gene mutation have a relative risk of approximately 3 for breast cancer compared to the general population. Cancer screening and risk-reducing options. In regard to colon...

5

RAD51C - PROMPT

http://promptstudy.info/geneinfo/rad51c

PROMPT in the Press. PROMPT in the Press. Gene play a role in how DNA repairs itself. Gene is classified as a moderate risk gene, meaning that there is a modestly increased risk for certain types of cancers. For example, women who have one. Pathogenic gene mutation have a relative risk for ovarian cancer of 5.2 compared to the general population. Further research is needed to understand the interactions of moderate risk genes and family history on lifetime cancer risk. Testing in other family members.

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PROMPT in the Press. PROMPT in the Press. YOU CAN HELP RESEARCHERS BETTER UNDERSTAND WHO IS AT RISK FOR HEREDITARY CANCER. Welcome to the Prospective Registry Of MultiPlex Testing (PROMPT). This online research registry for patients and their families helps researchers answer the question: How do genetic variants affect your cancer risk? If you’re here, you’ve likely undergone multiplex gene panel testing and were found to have a genetic variant that may be linked to an increased risk of cancer.

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