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resimmune.com

Angimmune LLC - Developer of Resimmune™, an Anti-T Cell Immunotoxin

Sponsor of Cutaneous T-cell Lymphoma clinical trial using A-dmDT390-bisFv (UCHT1) immunomodulation therapy for T-cell, cancer, and autoimmune diseases.

http://www.resimmune.com/

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Angimmune LLC - Developer of Resimmune™, an Anti-T Cell Immunotoxin | resimmune.com Reviews
<META>
DESCRIPTION
Sponsor of Cutaneous T-cell Lymphoma clinical trial using A-dmDT390-bisFv (UCHT1) immunomodulation therapy for T-cell, cancer, and autoimmune diseases.
<META>
KEYWORDS
1 approach
2 ctcl clinical trial
3 melanoma clinical trial
4 early results
5 future directions
6 t cell targeting
7 reference
8 sustained effect theory
9 angimmune's anti
10 t cell
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approach,ctcl clinical trial,melanoma clinical trial,early results,future directions,t cell targeting,reference,sustained effect theory,angimmune's anti,t cell,a dmdt390 bisfv ucht1,resimmune resimmune,applications,advantages,clinical trial,resimmune
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Angimmune LLC - Developer of Resimmune™, an Anti-T Cell Immunotoxin | resimmune.com Reviews

https://resimmune.com

Sponsor of Cutaneous T-cell Lymphoma clinical trial using A-dmDT390-bisFv (UCHT1) immunomodulation therapy for T-cell, cancer, and autoimmune diseases.

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resimmune.com resimmune.com
1

Angimmune LLC - Developer of Resimmune™, an Anti-T Cell Immunotoxin

http://www.resimmune.com/index.html

CLINICAL SITE LOG IN. For Cancers and Autoimmune Diseases. Immunotoxin is being investigated for treatment of Cutaneous T-Cell Lymphoma (CTCL), Melanoma, GI cancers and CD3 Autoimmune Diseases. A New Method to Induce Immunomodulation. Angimmune LLC is the developer of a high potency fusion protein anticancer immunotoxin Resimmune, or. Resimmune is an Anti-CD3 Immunotoxin that can be used to induce anti-tumor CD8 central memory T cell expansion following T cell depletion during homeostatic proliferation.

2

Our Approach - The Science Behind Angimmune's Anti-T Cell Therapy

http://www.resimmune.com/approach.html

CLINICAL SITE LOG IN. The critical components of Angimmune's unique anti-T cell therapy technology are the rational design of highly potent immunotoxin molecules and the system for high yield and low cost immunotoxin production in yeast. Expression system that is toxin-resistant and has the capacity to properly fold multi-domain proteins at high production rates. Advantages of the DT390 / Pichia. This unique bivalent anti-T cell immunotoxin therapy works in two ways:. High expression in P. pastoris.

3

Licensing and Collaboration Information and Inquiries - Angimmune LLC

http://www.resimmune.com/licensing.html

CLINICAL SITE LOG IN. Or A-dmDT390-bisFv(UCHT1) has been granted Orphan Drug Designation for the treatment of Cutaneous T-Cell Lymphoma (CTCL). Because a wide variety of antibody sequences can be used in the DT390/Pichia Platform, collaborations with other companies having proprietary antibodies may be mutually beneficial. Angimmune holds exclusive licenses from NIH of all intellectual property developed by Neville, Woo, and Liu. Licensing inquiries – US and worldwide. Please like us on Facebook.

4

Clinical Trials for Cutaneous T cell Lymphoma (CTCL) - Angimmune

http://www.resimmune.com/cutaneous-t-cell-lymphoma-clinical-trials.html

CLINICAL SITE LOG IN. Cutaneous T-Cell Lymphoma (CTCL) Pivotal Clinical Trial. FDA Approval of Pivotal Phase II Trial:. Safety and Effectiveness of. In Subjects with Mycosis Fungoides: A Phase II Multi-center Randomized Clinical Trial. Diagnosis and Main Inclusion and Exclusion Criteria:. To further explore the toxicity profile of A-dmDT390-bisFv(UCHT1) fusion protein for subjects with mycosis fungoides who have been selected to be free from preexisting cardiac disease and never treated with Campath.

5

About Angimmune - Developer of Resimmune™, an Anti-T Cell Immunotoxin

http://www.resimmune.com/company.html

CLINICAL SITE LOG IN. Angimmune is a clinical stage biotech company founded by. And two former members of his previous lab at the National Institutes of Health (NIH),. While at NIH these founders developed a unique immunotoxin technology. Angimmune has exclusively licensed this technology from NIH. Angimmune conducts research in a facility located at the American Red Cross Holland Laboratory, in Rockville, Maryland. Dr Yuan-Yi Liu, Ph.D. Dr Jung-Hee Woo, Ph.D. Dr Jung-Hee Woo is Director of Drug Manufact...

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CLINICAL SITE LOG IN. For Cancers and Autoimmune Diseases. Immunotoxin is being investigated for treatment of Cutaneous T-Cell Lymphoma (CTCL), melanoma, and other applications. Angimmune LLC is the developer of a high potency fusion protein anticancer immunotoxin,. Has been granted Orphan Drug Designation for the treatment of Cutaneous T-Cell Lymphoma (CTCL). This unique bivalent anti-T cell immunotoxin therapy works in two ways:. Kills malignant T cells, targeting the CD3 receptor. Can act as an immuno...

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