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What is Target Discovery? Research and core expertise. Mass Spectrometry for Target Discovery. Coordinated research needed to beat the next Ebola outbreak'. Writing in the journal. In that order to tackle the next Ebola outbreak, there must be agreement now on how to integrate research with the emergency medical response. She suggests pre-agreed plans for trials, addressing concerns such as data ownership and drug pricing in advance.

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Home - Target Discovery Institute | tdi.ox.ac.uk Reviews

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What is Target Discovery? Research and core expertise. Mass Spectrometry for Target Discovery. Coordinated research needed to beat the next Ebola outbreak'. Writing in the journal. In that order to tackle the next Ebola outbreak, there must be agreement now on how to integrate research with the emergency medical response. She suggests pre-agreed plans for trials, addressing concerns such as data ownership and drug pricing in advance.

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4 publications

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Home - Target Discovery Institute | tdi.ox.ac.uk Reviews

https://tdi.ox.ac.uk

What is Target Discovery? Research and core expertise. Mass Spectrometry for Target Discovery. Coordinated research needed to beat the next Ebola outbreak'. Writing in the journal. In that order to tackle the next Ebola outbreak, there must be agreement now on how to integrate research with the emergency medical response. She suggests pre-agreed plans for trials, addressing concerns such as data ownership and drug pricing in advance.

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tdi.ox.ac.uk

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Publications 2016 - Target Discovery Institute

http://www.tdi.ox.ac.uk/publications-2

Van de Bunt M. 2016 Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants. Diabetes. 2016 Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche. Cancer Cell. 2), Show Abstract. 2016 The retinoid agonist Tazarotene promotes angiogenesis and wound healing. Mol Ther. 2016 Parallel reverse genetic screening in mutant human cells using transcriptomics. Mol Syst Biol. 8), Show Abstract. 32), Show Abstract.

2

Outreach - Target Discovery Institute

http://www.tdi.ox.ac.uk/outreach-and-impact

Public Engagement at the TDI. Lidl BananaMan Triathlon July 2016. Researchers from the Kessler group participated to a team relay triathlon in July 2016 and were able to collect £111 for "CLIC Sargent for children with Cancer". Team 1 : Honglei Huang, Adan Pinto Fernandez and Marie-Laëtitia Thézénas. Team 2 : Benedikt Kessler, Annalisa Nicastri and Simon Davis. WOLF RUN September 2015. The Great Oxford Bake Off 2015. Wear it pink and pink cake sale 24th October 2014. Andrea Keyte, Roman Fischer, Ling Jin...

3

Cellular HTS - Target Discovery Institute

http://www.tdi.ox.ac.uk/high-throughput-screening

ARUK Oxford Drug Discovery Institute. Cellular High Throughput Screening (HTS). The HTS team of researchers is lead by Daniel Ebner. Major investment in the group has enabled the procurement of high end, state-of-the-art screening equipment; consisting of liquid handling automation, multiplatform plate readers and high content imaging equipment. This investment results in a facility which is able to produce highly complex and diverse screens. BHF Cardiovascular Target Discovery.

4

Quantitative Imaging - Target Discovery Institute

http://www.tdi.ox.ac.uk/quantitative-imaging

ARUK Oxford Drug Discovery Institute. 1 Analysis of shape, structure, and spatial context. 2 Function and dynamic biological processes. 3 Enablement of new imaging methods. 2016 Offices of the Nuffield Professor of Medicine, Nuffield Department of Medicine, University of Oxford. Henry Wellcome Building for Molecular Physiology, Old Road Campus, Headington, Oxford OX3 7BN.

5

Pharmacogenomics - Target Discovery Institute

http://www.tdi.ox.ac.uk/pharmacogenomics

ARUK Oxford Drug Discovery Institute. Our research is focused on understanding how drugs work in the complex context of genetic heterogeneity, and the identification of novel drug targets for cancer therapy. To achieve this we employ various functional genomic screening and systems biology approaches. The Pharmacogenomics group is led by Professor Sebastian Nijman. 2016 Offices of the Nuffield Professor of Medicine, Nuffield Department of Medicine, University of Oxford.

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ndmrb.ox.ac.uk

About - NDM Research Building

http://www.ndmrb.ox.ac.uk/about

The Li Ka Shing Centre. About the NDM Research Building. The NDM Research Building is a new medical research building on the Old Road Campus. This £22M new building is part of the Nuffield Department of Medicine. And will allow development of the Target Discovery Institute. And expansion of existing research groups of NDM with research synergies such as Respiratory Medicine. The building is also home to one of two sites for the Centre for Tropical Medicine and Global Health. Situated on the 1. The Viral ...

eucai.org

Oxford TDI - European Cell-based Assays Interest Group

http://www.eucai.org/oxford-tdi.html

European Cell-based Assays Interest Group. Go to TDI website. University of Oxford - Target Discovery Institute.

oxsync.chem.ox.ac.uk

Links and Downloads

http://oxsync.chem.ox.ac.uk/more.aspx

How We Can Help. Supported in part by OxSynC, Prof David Hodgson (Chemistry) and Dr Kenny Moore (Pathology) collaborated to test. Hyperolactone C and analogues as potential inhibitors of HIV-1 replication. This work has recently been reported in the. Journal of Organic Chemistry. OxSynC will be presenting at the Begbroke coffee morning on the 28th November. The Autumn 2012 newsletter is now available. OxSynC awarded a 6 month PDRA grant. 2nd drop-in session at the WIMM. Introduction to OxSynC presentatio...

sciberomics.com

Public-private collaborations Drive Drug Development

http://sciberomics.com/articles/partnerships-3

Snapshots of Science and Life. NGS in the Clinic. NGS – Challenges. Public-Private Collaborations To Drive Successful Drug Development. Original article published on Assay Depot Blog, on 27 May 2014 here. The key to fighting chronic diseases is connecting the multitude of scientific and technological advances to diagnostics and therapeutics. Experts have recognized that to efficiently achieve this connection, a truly collaborative approach to drug discovery and development. Increased efficiency - Reducin...

drugdiscovery.chem.ox.ac.uk

Automated Screening

http://drugdiscovery.chem.ox.ac.uk/Experts/page16

Medical Devices and Diagnostics. Pre-Clinical and Clinical Imaging. Protein and Peptide Chemistry. Virtual Libraries and Screening. Medical Devices and Diagnostics. Pre-Clinical and Clinical Imaging. Protein and Peptide Chemistry. Virtual Libraries and Screening. BHF Professor of Cardiovascular Medicine Department of Cardiovascular Medicine. Cardiovascular medicine, cell signalling, high throughput screening. Waynflete Professor of Chemistry, Department of Chemistry. Page last updated: 10/09/2013.

ndmrb.ox.ac.uk

TDI - NDM Research Building

http://www.ndmrb.ox.ac.uk/tdi

Target Discovery Institute Research. Mass Spectrometry for Target Discovery. A key technology for the discovery and characterisation of critical molecules and pathways in disease is based on mass spectrometry. Defining molecular targets and also converting lead compounds affecting these targets into drug candidates are crucial steps in drug development, requiring early assessment of potency, selectivity, and off-target effects. Dramatic technological improvements in. High Throughput Screening Facility.

drugdiscovery.chem.ox.ac.uk

Compound Screening Libraries

http://drugdiscovery.chem.ox.ac.uk/Experts/page21

Medical Devices and Diagnostics. Pre-Clinical and Clinical Imaging. Protein and Peptide Chemistry. Virtual Libraries and Screening. Medical Devices and Diagnostics. Pre-Clinical and Clinical Imaging. Protein and Peptide Chemistry. Virtual Libraries and Screening. Principal Investigator in Medicinal Chemistry, Structural Genomic Consortium (SGC). And Nuffield Department of Medicine. Medicinal chemistry, molecular modelling, epigenetics, chemical biology, compound screening libraries.

drugdiscovery.chem.ox.ac.uk

Experts

http://drugdiscovery.chem.ox.ac.uk/Experts

Medical Devices and Diagnostics. Pre-Clinical and Clinical Imaging. Protein and Peptide Chemistry. Virtual Libraries and Screening. Medical Devices and Diagnostics. Pre-Clinical and Clinical Imaging. Protein and Peptide Chemistry. Virtual Libraries and Screening. This section of the website contains an alphabetical list of our drug discovery experts. These people have been assigned a set of key skills in order to help you determine who may be most relevant to your interests. Protein and Peptide Chemistry.

ludwig.ox.ac.uk

About - Ludwig Institute for Cancer Research

http://www.ludwig.ox.ac.uk/ludwig

Nuffield Department of Medicine. Old Road Campus Research Building. The Oxford Branch of the Ludwig Institute for Cancer Research is based within the Nuffield Department of Medicine at the University of Oxford. Founded in 2007, the unit is mainly housed in the Old Road Campus Research Building. Some groups are within the nearby Target Discovery Institute. Is an international collaborative network of acclaimed scientists with a 40-year legacy of pioneering cancer discoveries.

ludwig.ox.ac.uk

About - Ludwig Institute for Cancer Research

http://www.ludwig.ox.ac.uk/about-ludwig

Nuffield Department of Medicine. Old Road Campus Research Building. The Oxford Branch of the Ludwig Institute for Cancer Research is based within the Nuffield Department of Medicine at the University of Oxford. Founded in 2007, the unit is mainly housed in the Old Road Campus Research Building. Some groups are within the nearby Target Discovery Institute. Is an international collaborative network of acclaimed scientists with a 40-year legacy of pioneering cancer discoveries.

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WHAT WE’VE DONE. WHAT WE’VE DONE. How can you engage? Hear directly from our team. MEET THE TDi TEAM. AT OUR NEXT BREAKFAST FORUM. Can we help you? At The Difference Incubator (TDi) we grow Investable Social Enterprises (ISEs). Our focus is on helping bridge the gap between social enterprises and impact investors through targeted capacity building. See how we make a difference. And watch the video below to find out more about what we do. August 21, 2015. Sign up to stay updated. Level 1, 673 Bourke Street.

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Skip to main content. Make your space safer. Leisurewatch can help protect your facilities from sexual offending and concerning behaviour. Tailored training courses for those who work with sex offenders in a range of settings delivered by our experts. Learn more about offenders. In-depth research into some of the key issues around sexual offending. Tackling sexual offending together. Our goals: safer individuals, safer public spaces, safer communities. To Check Or Not To Check? Make your space safer.

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Home - Target Discovery Institute

What is Target Discovery? Research and core expertise. Mass Spectrometry for Target Discovery. Coordinated research needed to beat the next Ebola outbreak'. Writing in the journal. In that order to tackle the next Ebola outbreak, there must be agreement now on how to integrate research with the emergency medical response. She suggests pre-agreed plans for trials, addressing concerns such as data ownership and drug pricing in advance.

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